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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
59 Results for "
PTX
" in MedChemExpress (MCE) Product Catalog:
Products (59)
59 Results for "PTX" in MCE Product Catalog:
18
2
2 Cited Publications
Cat. No.: HY-P71067
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: APCS; Pentraxin-2; Amyloid P Component, Serum; MGC88159; PTX2; Epididymis Secretory Sperm Binding Protein Li 92n; SAP; Pentraxin Family Member; 9.5S Alpha-1-Glycoprotein; Pentaxin-Related; Serum Amyloid P-Component; HEL-S-92n; Pentraxin-Related
Species:
Human
Source:
HEK293
1
1
1 Cited Publications
Cat. No.: HY-P71246
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PTX3; Long Pentraxin 3; Prev. TNFAIP5; Pentaxin-Related Gene, Rapidly Induced By IL-1 Beta; TSG-14; Tumor Necrosis Factor, Alpha-Induced Protein 5; Tumor Necrosis Factor-Inducible Gene 14 Protein; Tumor Necrosis Factor-Inducible Protein TSG-14; Tumor Necr
Species:
Mouse
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P73714
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PTX3; Long Pentraxin 3; Prev. TNFAIP5; Pentaxin-Related Gene, Rapidly Induced By IL-1 Beta; TSG-14; Tumor Necrosis Factor, Alpha-Induced Protein 5; Tumor Necrosis Factor-Inducible Gene 14 Protein; Tumor Necrosis Factor-Inducible Protein TSG-14; Tumor Necr
Species:
Human
Source:
HEK293
Target:
Research Areas:
6α-Hydroxy paclitaxel is one of the main metabolites of Paclitaxel (PTX) (HY-B0015), and it is generated by the liver cytochrome P450 enzyme CYP2C8. 6α-Hydroxy paclitaxel has bone marrow toxicity, but it can enhance the cytotoxicity of PTX against leukemia cells without causing cell toxicity. 6α-Hydroxy paclitaxel can be used in leukemia research .
Category:
Cardiacglycosides Other Diseases Plants Disease Research Fields Apocynum Apocynaceae Extract Steroids
Target:
Cat. No.: HY-W273690
CAS No.: 1028-33-7
Synonyms: 1-Hexyltheobromine; Hexyltheobromine
Target:
Research Areas:
Pentifylline (1-Hexyltheobromine; Hexyltheobromine), PTX (HY-B0715) precursor compound, is a vasodilator. Pentifylline decreases procollagen levels and inhibits collagen production. Pentifylline reduces functional nuclear NF-1 to suppress procollagen gene transcription .
Target:
Research Areas:
WS-898 is a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC50 = 5.0, 3.67, and 3.68 nM, respectively).
Cat. No.: HY-P991455
Target:
Research Areas:
Cat. No.: HY-146034
CAS No.: 2704623-69-6
Target:
Research Areas:
NOD1/2 antagonist-1 (compound 36b) is a potent NOD1/2 (nucleotide-binding
oligomerization domain-like receptor 1/2) dual antagonist, with IC50 values of 1.13 (NOD1) and 0.77 μM (NOD2), respectively. NOD1/2 antagonist-1 has a acceptable T1/2 (67.6 min). NOD1/2 antagonist-1 (compound 36b) can improve the antitumor efficacy of Paclitaxel (PTX) .
Cat. No.: HY-178078
CAS No.: 1800077-28-4
Target:
Research Areas:
PTX-SS-COOH is the proform that can be grafted to the sulfhydryl modified gelatin to form the redox sensitive amphiphilic polymer. The nanoparticle (BSA/Gel-SS-PTX/PTX-SS-COOH NPs) demonstrates an excellent anticancer efficiency. PTX-SS-COOH can be applied in the research of targeted delivery for solid tumors (such as breast cancer and melanoma) by utilizing the unique characteristics of the tumor microenvironment (high GSH level) .
Category:
Flavonoids Chalcones Leguminosae Extract Plants Brachypterum robustum (Roxburgh ex Candolle) Dalzell & Gibson
Target:
Cat. No.: HY-157529
CAS No.: 2250419-19-1
Target:
Research Areas:
IR820-PTX, an IR-820 (HY-136886)-Paclitaxel (HY-B0015) conjugate, is an amphipathic small molecule prodrug. IR820-PTX effectively inhibits tumor growth via combined photothermal therapy (PTT) and chemotherapy .
Cat. No.: HY-P11018
Research Areas:
Cat. No.: HY-148750
CAS No.: 1627834-10-9
Synonyms: BD10-2
Target:
Research Areas:
PTX-BD10-2 (BD10-2) is an orally active TrkB/C modulator. PTX-BD10-2 ameliorates BFCN degeneration. PTX-BD10-2 restores cholinergic neurite integrity, alleviates cholinergic neurite atrophy. PTX-BD10-2 can be used in the research of Alzheimer's disease .
Cat. No.: HY-177482
CAS No.: 3011748-20-9
Target:
Research Areas:
Pro-PTX is a Pd-sensitive Paclitaxel (HY-B0015) prodrug with anticancer activity. Pro-PTX triggers intramolecular cyclization via Pd-catalyzed depropargylation to release active Paclitaxel (HY-B0015) and a non-toxic byproduct. Pro-PTX exhibits low cytotoxicity and antiproliferative activity in cancer cells and non-cancerous human cerebrovascular pericytes. Pro-PTX is applicable for research related to non-small cell lung cancer, glioblastoma and lung cancer .
Cat. No.: HY-RS11458
Target:
Research Areas:
PTX4 Human Pre-designed siRNA Set A contains three designed siRNAs for PTX4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
