Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
39 Results for "
Runx2
" in MedChemExpress (MCE) Product Catalog:
Products (39)
39 Results for "Runx2" in MCE Product Catalog:
11
Target:
Research Areas:
Muramyl dipeptide (MDP) is a synthetic immunoreactive peptide, consisting of N-acetyl muramic acid attached to a short amino acid chain of L-Ala-D-isoGln. Muramyl dipeptide is an inducer of bone formation through induction of Runx2. Muramyl dipeptide directly enhances osteoblast differentiation by up-regulating Runx2 gene expression through MAPK pathways. Muramyl dipeptide is a NLRP1 agonist [2].
11
11 Publications Verification
Synonyms: 2-Phospho-L-ascorbic acid magnesium; LAA2P magnesium
11
11 Publications Verification
Synonyms: 2-Phospho-L-ascorbic acid trisodium
11
11 Publications Verification
Synonyms: 2-Phospho-L-ascorbic acid; LAA2P
11
11 Publications Verification
Synonyms: 2-Phospho-L-ascorbic acid magnesium hydrate; LAA2P magnesium hydrate
6
6 Cited Publications
Cat. No.: HY-P80316
Synonyms: AML3, CBFA1, OSF2, PEBP2A, Runx2, Runt-related transcription factor 2, Acute myeloid leukemia 3 protein, Core-binding factor subunit alpha-1, Oncogene AML-3, Osteoblast-specific transcription factor 2, Polyomavirus enhancer-binding protein 2 alpha A subunit, SL3-3 enhancer factor 1 alpha A subunit, SL3/AKV core-binding factor alpha A subunit, CBF-alpha-1, OSF-2, PEA2-alpha A, PEBP2-alpha A
5
5 Cited Publications
Target:
Research Areas:
CADD522 is a RUNX2-DNA binding inhibitor (downregulates RUNX2-mediated transcription of downstream target genes), with an IC50 of 10 nM. CADD522 inhibits primary tumor growth and experimental metastasis of tumor cells in the lungs of immune-compromised mice. CADD522 can be used in study of cancer [2].
1
1 Cited Publications
Cat. No.: HY-P5522A
Synonyms: L-Ala-γ-D-Glu-meso-diaminopimelic acid dihydrochloride
Research Areas:
Cat. No.: HY-W014410
CAS No.: 526-99-8
Category:
Microorganisms Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields
Target:
Cat. No.: HY-N4119
CAS No.: 13241-32-2
Category:
other families Flavonoids Flavonones Phenols Polyphenols Plants
Cat. No.: HY-P5832
CAS No.: 836606-84-9
Target:
Research Areas:
Cat. No.: HY-103322
CAS No.: 1135306-29-4
Target:
Research Areas:
6-Bnz-cAMP sodium, a derivative of cyclic adenosine monophosphate (cAMP), is a selective PKA activator with inhibitory activity against the bTREK-1 K + channel. 6-Bnz-cAMP sodium does not activate the Epac signaling pathway. It inhibits the bTREK-1 K + channel via a voltage-independent, ATP-dependent mechanism that is independent of the PKA/Epac/calmodulin kinase/MAP kinase pathway. 6-Bnz-cAMP sodium activates CREB phosphorylation to regulate osteoblast-specific gene expression, induces osteoblast differentiation, promotes extracellular matrix mineralization, supports osteoblast proliferation, and shows no cytotoxicity toward osteoblasts. It can be used in studies related to bone tissue repair and regeneration [2] .
Cat. No.: HY-RS12351
Target:
Research Areas:
RUNX2 Human Pre-designed siRNA Set A contains three designed siRNAs for RUNX2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-W019901B
CAS No.: 7778-18-9
Synonyms: Gypsum ustum (97%)
Cat. No.: HY-RS16864
Target:
Research Areas:
Runx2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Runx2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-N2156
CAS No.: 72520-92-4
Cat. No.: HY-N0946
CAS No.: 41607-20-9
Synonyms: (-)-Pinoresinol 4-O-β-D-glucopyranoside
Target:
Cat. No.: HY-143678
CAS No.: 2468149-70-2
Target:
Research Areas:
Citrulline-specific probe-biotin is a biotinylated probe for detection of citrulline. Citrulline is the hydrolysis product of arginine catalyzed by protein arginine deiminase (PAD). PAD is abnormally activated in many diseases, leading to increased citrulline levels. Citrulline-specific probe-biotin is a biological probe that can identify diseases showing abnormal increases in PAD activity .
- 1
- 2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
