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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
30 Results for "
SMS
" in MedChemExpress (MCE) Product Catalog:
Products (30)
30 Results for "SMS" in MCE Product Catalog:
16
Target:
Research Areas:
Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
16
Target:
Research Areas:
Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
4
4 Cited Publications
Cat. No.: HY-163541
Research Areas:
SMS121 is a CD36 inhibitor with a KD values of about 5 µM. SMS121 reduces the uptake of lipids and inhibits cell viability in acute myeloid leukemia cells. SMS121 has antitumor activity .
3
3 Cited Publications
Cat. No.: HY-N8518
CAS No.: 63335-25-1
Category:
Metabolic Disease Phenols Polyphenols Myristicaceae Plants Myristica fragrans Houtt. Disease Research Fields
Target:
3
3 Cited Publications
Target:
Research Areas:
Ly93 is a selective and orally active sphingomyelin synthase 2 (SMS2) inhibitor, with an IC50 of 91 nM .
3
3 Cited Publications
Target:
Research Areas:
SMS2-IN-1 is a potent and highly selective sphingomyelin synthase 2 (SMS2) inhibitor with an IC50 of 6.5 nM and a Kd of 37 nM. SMS2-IN-1 shows 150-fold selectivity for SMS2 over SMS1 (IC50 of 1000 nM) .
Cat. No.: HY-19625
CAS No.: 1162656-22-5
Research Areas:
MCB-613 is a potent Steroid receptor coactivator SRC small molecule ‘stimulator’ (SMS), super-stimulates SRCs’ transcriptional activity.
MCB-613 increases SRCs’ interactions with other coactivators and markedly induces ER stress coupled to the generation of reactive oxygen species (ROS).
MCB-613 is a SMS that target oncogenes can be exploited as anti-cancer agents by over-stimulating the SRC oncogenic program .
Target:
Research Areas:
SMS1-IN-1, compound SAPA 1j, is a novel and the most potent sphingomyelin synthase 1 (SMS1) inhibitor with an IC50 value of 2.1 μM. SMS1-IN-1 has the potential for the treatment of atherosclerosis .
Target:
Research Areas:
SMS2-IN-2 is a potent, highly selective and orally active sphingomyelin synthase 2 (SMS2) inhibitor, with IC50s of 100 nM and 56 μM for SMS2 and SMS1, respectively. Anti-chronic inflammatory activity .
Cat. No.: HY-165136
CAS No.: 475662-40-9
Synonyms: SMS (buttermilk)
Target:
Research Areas:
Sphingomyelins, milk (SMs (buttermilk)) are compounds studied in sphingolipids, which play important roles in various biological processes.
Cat. No.: HY-P0036A
CAS No.: 1607842-55-6
Synonyms: SMS 201-995 dihydrochloride
Target:
Research Areas:
Cat. No.: HY-150559
CAS No.: 2414240-89-2
Target:
SMS2-IN-3 is a potent and selective SMS2inhibitor (IC50=2.2 nM), significantly reduces the hepatic SM (22:0) levels .
Cat. No.: HY-P0036S4
Synonyms: SMS 201-995-d8 acetate
Cat. No.: HY-P0036B
CAS No.: 135467-16-2
Synonyms: SMS 201-995 pamoate
Target:
Research Areas:
Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
Cat. No.: HY-RS13454
Target:
Research Areas:
SMS Human Pre-designed siRNA Set A contains three designed siRNAs for SMS gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-N8518R
CAS No.: 63335-25-1
Cat. No.: HY-P0036S2
CAS No.: 1240797-41-4
Synonyms: SMS 201-995-d8
Cat. No.: HY-P0036S3
Synonyms: SMS 201-995-13C9，15N
Cat. No.: HY-139995
CAS No.: 2576358-68-2
Target:
Research Areas:
Spermine precursor-1 (Compound 1) is a redox-sensitive spermine precursor for the potential research of snyder robinson syndrome. Spermine precursor-1 inhibits wild-type (CMS-24949) and spermine synthase gene (SMS) mutant (CMS-26559, and CMS-6233) fibroblast cells with IC50s of 326.7, 198.5, and 244.1 μM, respectively .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
