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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
22 Results for "
SPT
" in MedChemExpress (MCE) Product Catalog:
Products (22)
22 Results for "SPT" in MCE Product Catalog:
12
12 Publications Verification
Cat. No.: HY-N6798
CAS No.: 35891-70-4
Synonyms: Thermozymocidin; ISP-I
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SGF29-IN-1 (Compound Cpd_DC60) is a selective inhibitor for Spt-Ada-Gcn5 acetyltransferase (SAGA)–associated factor 29 (SGF29)-Tudor domain. SGF29-IN-1 exhibits activity against leukemia .
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1 Cited Publications
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SPT-IN-1 (compound 1) is an orally active and potent SPT (serine palmitoyl transferase) inhibitor, with an IC50 of 5.19 nM for hSPT1. SPT-IN-1 can be used for type 2 diabetes and dyslipidemia research .
Cat. No.: HY-170794
CAS No.: 2035010-37-6
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ALT-007 is an orally active serine palmitoyltransferase (SPT) inhibitor that selectively reduces the levels of toxic very-long-chain deoxysphingolipids to enhance protein homeostasis. ALT-007 restores aging-related loss of muscle mass in a mouse model of sarcopenia. ALT-007 enhances protein homeostasis in both mouse and C. elegans models of aging and disease. ALT-007 can be used for age-related neuromuscular diseases research .
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Cat. No.: HY-W688565
CAS No.: 18944-28-0
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(2S)-2-Amino-1-hydroxyoctadecan-3-one is the product generated by the decarboxylative condensation of L-serine and palmitoyl-CoA catalyzed by serine palmitoyltransferase (SPT) .
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ARN14494 is a potent and selective serine palmitoyltransferase (SPT) inhibitor, with an IC50 of 27.3 nM. ARN14494 affects the CNS in terms of anti-inflammation and neuroprotection. ARN14494 protects neurons from β-amyloid 1-42-induced neurotoxicity through a variety of mechanisms, including anti-oxidation, anti-apoptosis, and anti-inflammation. ARN14494 can be used for Alzheimer’s disease research .
Cat. No.: HY-129092
CAS No.: 80206-91-3
Synonyms: 8-SPT; 8-pSPT
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8-(p-Sulfophenyl)theophylline (8-SPT) (compound 2) is an adenosine A2B receptor antagonist, with a Ki of 1330 nM for A2B human recombinant .
Cat. No.: HY-RS00473
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AGXT Human Pre-designed siRNA Set A contains three designed siRNAs for AGXT gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-181943
CAS No.: 2035011-97-1
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SPT-IN-2 is an orally active serine palmitoyltransferase (SPT) inhibitor (with an IC50 of 0.71 nM against human SPT2). SPT-IN-2 inhibits ceramide synthesis, suppresses cancer cell growth, and exhibits in vivo anti-tumor activity, favorable metabolic stability and cell membrane permeability in xenograft mouse models. SPT-IN-2 blocks the de novo sphingolipid synthesis pathway, significantly reducing intracellular ceramide levels and the levels of 3-ketodihydrosphingosine (3-KDS), the immediate downstream product of SPT. SPT-IN-2 can be used in research related to lung adenocarcinoma, acute promyelocytic leukemia and breast cancer .
Cat. No.: HY-N6798R
CAS No.: 35891-70-4
Synonyms: Thermozymocidin (Standard); ISP-I (Standard)
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Cat. No.: HY-N20677
CAS No.: 1151683-53-2
Target:
Cat. No.: HY-P82275A
Synonyms: AGT; PH1; SPT; AGT1; SPAT; TLH6; AGXT1
Cat. No.: HY-P703421
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: FACT complex subunit SPT16; Facilitates chromatin transcription complex subunit SPT16; SPT16; Arabidopsis thaliana; Mouse-ear cress
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
