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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
41 Results for "
Selenium
" in MedChemExpress (MCE) Product Catalog:
Products (41)
41 Results for "Selenium" in MCE Product Catalog:
35
35 Publications Verification
Research Areas:
NCT-503 is a blood-brain barrier-permeable, non-competitive PHGDH inhibitor with an IC50 of 2.5 μM against human PHGDH. NCT-503 reduces glucose-derived serine production and the incorporation of one-carbon units into nucleotides without decreasing PHGDH protein expression. NCT-503 prevents high selenium-induced insulin resistance in mice by regulating blood glucose and insulin levels and improving glucose tolerance, and also inhibits the growth of tumors overexpressing PHGDH. NCT-503 can be used in research related to insulin resistance and breast cancer .
12
12 Cited Publications
Synonyms: Seleno-DL-methionine; DL-Selenomethionine
Category:
Disease markers Amino acids Nervous System Disorder Prostate Cancer Markers Endogenous metabolite Disease Research Fields Cancer
Target:
11
5
Category:
Plant Ketones, Aldehydes, Acids Animal Other Families Extract Microorganism Endogenous metabolite Disease Research Fields Cancer
Target:
2
2 Cited Publications
Research Areas:
Cat. No.: HY-150287A
Synonyms: ITS-X
Cat. No.: HY-W094507
CAS No.: 1313-85-5
Cat. No.: HY-W012898
CAS No.: 95-45-4
Synonyms: Biacetyl dioxime
Target:
Research Areas:
Dimethylglyoxime (Biacetyl dioxime) is an oxime compound. Dimethylglyoxime selectively coordinates with divalent nickel ions Ni 2+ to form stable complexes, and can also coordinate with copper ions Cu 2+, but does not coordinate with iron, selenium or zinc. Dimethylglyoxime inhibits the aggregation of human β-amyloid 40 peptide in vitro. Dimethylglyoxime is used in the research of Alzheimer's disease .
Cat. No.: HY-119973
CAS No.: 78028-01-0
Target:
Research Areas:
CAY10397 is a selective and orally active 15-hydroxyprostaglandin dehydrogenase (15-PGDH) inhibitor. CAY10397 can inhibit 15-PGDH-dependent endogenous metabolite production. CAY10397 blocks the selenium-dependent protective in inflammation. CAY10397 can be used for the research of colitis .
Synonyms: Seleno-DL-methionine (Standard); DL-Selenomethionine (Standard)
Category:
Amino acids Nervous System Disorder Microorganism Prostate Cancer Markers Endogenous metabolite Cancer
Target:
Cat. No.: HY-B1000AR
CAS No.: 3211-76-5
Synonyms: L-SeMet (Standard)
Cat. No.: HY-150287B
Synonyms: ITS-A
Cat. No.: HY-B1000S1
CAS No.: 1414810-73-3
Cat. No.: HY-W017224
CAS No.: 2386-54-1
Synonyms: Sodium 1-butanesulfonate
Cat. No.: HY-W653841
CAS No.: 39455-18-0
Target:
Research Areas:
Chondroitin sulfate A disodium is a mucopolysaccharide extracted from animal cartilages such as porcine nasal cartilage, and serves as a major structural component of cartilage. Chondroitin sulfate A disodium is one of the specific receptors for the adhesion of Plasmodium falciparum-infected red blood cells in the microcirculation. Chondroitin sulfate A disodium can be used together with selenium to prepare nanoparticles for protecting cartilage against T‑2 toxin-induced damage. Chondroitin sulfate A disodium is abnormally highly expressed in ameloblastoma, and is particularly enriched in stellate reticulum-like tumor cells. Chondroitin sulfate A disodium can be applied to studies on Plasmodium infection mechanisms, cartilage protection and oral tumors .
Cat. No.: HY-120914
CAS No.: 170950-29-5
Synonyms: GO-Y015
Target:
Glutathione Peroxidase Keap1-Nrf2 Heme Oxygenase (HO) Reactive Oxygen Species (ROS) Apoptosis Mitochondrial Metabolism Drug Derivative TrxR
Research Areas:
TrxR1-IN-B19 (GO-Y015) is a Curcumin (HY-N0005) derivative and TrxR1 inhibitor. TrxR1-IN-B19 inhibits de novo selenoprotein synthesis, suppresses SeP and GPx expression, and impairs selenium incorporation into Sec-tRNA[Sec]. TrxR1-IN-B19 induces Nrf2 accumulation through Keap1 cysteine modification, HO-1 expression, GSH synthesis, ROS accumulation, ER stress, mitochondrial dysfunction, Apoptosis, and G2/M phase arrest. TrxR1-IN-B19 improves glucose tolerance and insulin sensitivity, lowers blood glucose, inhibits tumor growth, and reduces arsenic accumulation. TrxR1-IN-B19 can be used for research on type 2 diabetes, arsenite-induced toxicity, and gastric cancer .
Cat. No.: HY-117429
CAS No.: 1850293-95-6
Synonyms: Selenium-acetylsalicylic acid
Target:
Research Areas:
Se-Aspirin is a hybrid molecule of selenium and Aspirin (HY-14654). Se-Aspirin reduces the viability of cancer cell lines, particularly colorectal cancer cells .
Cat. No.: HY-W585825
CAS No.: 2578-27-0
Target:
Research Areas:
Selenoethionine is a selenium-containing amino acid .
Cat. No.: HY-114851
CAS No.: 26046-89-9
Synonyms: GMSeC
Methylselenocarboxyethylglutamine (GMSeC) is an organic selenium compound that shows no in vitro anti-cancer activity against colon cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
