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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
35 Results for "
Selenium
" in MedChemExpress (MCE) Product Catalog:
Products (35)
35 Results for "Selenium" in MCE Product Catalog:
32
32 Publications Verification
Research Areas:
NCT-503 is a blood-brain barrier-permeable, non-competitive PHGDH inhibitor with an IC50 of 2.5 μM against human PHGDH. NCT-503 reduces glucose-derived serine production and the incorporation of one-carbon units into nucleotides without decreasing PHGDH protein expression. NCT-503 prevents high selenium-induced insulin resistance in mice by regulating blood glucose and insulin levels and improving glucose tolerance, and also inhibits the growth of tumors overexpressing PHGDH. NCT-503 can be used in research related to insulin resistance and breast cancer .
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11 Cited Publications
Synonyms: Seleno-DL-methionine; DL-Selenomethionine
Category:
Microorganisms Disease markers Amino acids Nervous System Disorder Endogenous metabolite Disease Research Fields Cancer
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5
Category:
other families Microorganisms Animals Ketones, Aldehydes, Acids Plants Endogenous metabolite Disease Research Fields Cancer
Target:
2
2 Cited Publications
Research Areas:
Cat. No.: HY-150287A
Synonyms: ITS-X
Cat. No.: HY-163080S
CAS No.: 14681-72-2
Synonyms: 77Se
Cat. No.: HY-119973
CAS No.: 78028-01-0
Target:
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CAY10397 is a selective and orally active 15-hydroxyprostaglandin dehydrogenase (15-PGDH) inhibitor. CAY10397 can inhibit 15-PGDH-dependent endogenous metabolite production. CAY10397 blocks the selenium-dependent protective in inflammation. CAY10397 can be used for the research of colitis .
Cat. No.: HY-B1000AR
CAS No.: 3211-76-5
Synonyms: L-SeMet (Standard)
Synonyms: Seleno-DL-methionine (Standard); DL-Selenomethionine (Standard)
Category:
Microorganisms Disease markers Amino acids Nervous System Disorder Endogenous metabolite Cancer
Target:
Cat. No.: HY-150287B
Synonyms: ITS-A
Cat. No.: HY-W017224
CAS No.: 2386-54-1
Synonyms: Sodium 1-butanesulfonate
Cat. No.: HY-B1000S1
CAS No.: 1414810-73-3
Cat. No.: HY-178941
Research Areas:
DHODH-IN-32 (Compound A1) is a DHODH inhibitor. DHODH-IN-32 shows significant cytotoxicity against NCI-60 cell lines, especially being sensitive to breast cancer, prostate cancer and leukemia cell lines. DHODH-IN-32 can induce cell apoptosis by activating the Caspase pathway. DHODH-IN-32 causes G0/G1 phase cell cycle arrest and inhibits cellular metabolism by ROS. DHODH-IN-32 exhibits significant anti-tumor properties in mouse breast cancer models. DHODH-IN-32 can be used for the study of breast cancer .
Cat. No.: HY-W653841
CAS No.: 39455-18-0
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Chondroitin sulfate A disodium is a mucopolysaccharide extracted from animal cartilages such as porcine nasal cartilage, and serves as a major structural component of cartilage. Chondroitin sulfate A disodium is one of the specific receptors for the adhesion of Plasmodium falciparum-infected red blood cells in the microcirculation. Chondroitin sulfate A disodium can be used together with selenium to prepare nanoparticles for protecting cartilage against T‑2 toxin-induced damage. Chondroitin sulfate A disodium is abnormally highly expressed in ameloblastoma, and is particularly enriched in stellate reticulum-like tumor cells. Chondroitin sulfate A disodium can be applied to studies on Plasmodium infection mechanisms, cartilage protection and oral tumors .
Cat. No.: HY-156558
CAS No.: 1365541-49-6
Target:
Cat. No.: HY-117429
CAS No.: 1850293-95-6
Synonyms: Selenium-acetylsalicylic acid
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Research Areas:
Se-Aspirin is a hybrid molecule of selenium and Aspirin (HY-14654). Se-Aspirin reduces the viability of cancer cell lines, particularly colorectal cancer cells .
Cat. No.: HY-W585825
CAS No.: 2578-27-0
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Selenoethionine is a selenium-containing amino acid .
Cat. No.: HY-151188
Target:
Research Areas:
DHU-Se1 is a potent anti-inflammatory agent. DHU-Se1 can stimulate macrophages to release the reactive selenium compound and reduce the expression of cellular inflammatory factors (eg: iNOS and TNF-α). DHU-Se1 alleviate the process of inflammation by blocking the polarization of macrophages from M0 to M1 .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
