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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
21 Results for "
TRP-2
" in MedChemExpress (MCE) Product Catalog:
Products (21)
21 Results for "TRP-2" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-P2031
CAS No.: 26645-35-2
Target:
Cat. No.: HY-N2983
CAS No.: 32884-36-9
Category:
Flavonoids Other Diseases Phenols Polyphenols Red seaweeds Leguminosae Extract Plants Disease Research Fields Isoflavones
Target:
Cat. No.: HY-P2527
CAS No.: 187671-49-4
Target:
Domaines de recherche:
Tyrosinase-related Protein 2 (TRP-2) (181-188) is a peptide epitope of the TRP-2 protein that conforms to the MHC class I H2-Kb binding motif. It is the major reactive epitope within TRP-2 recognized by anti-B16 CTLs, induces TRP-2-specific CTL and CD8 + T cell responses, and mediates antibody-dependent antitumor effects against lung metastasis. Tyrosinase-related Protein 2 (TRP-2) (181-188) is used in melanoma research [2] .
Cat. No.: HY-134046
CAS No.: 10391-08-9
Synonyms: Isodocarpin
Category:
Target:
Target:
TSPO TRP Channel Microphthalmia Associated Transcription Factor (MITF) PKC PKA p38 MAPK PERK Interleukin Related
Domaines de recherche:
FGIN-1-27 is a blood-brain barrier-penetrant TSPO ligand with a Ki value of 5 nM. FGIN 1-27 inhibits PKC-β, PKA/CREB, p38/ERK MAPK, MITF, tyrosinase, TRP-1, and TRP-2, thereby inhibiting melanogenesis and pigmentation. FGIN-1-27 alleviates X-ray radiation-induced astrocyte mitochondrial hyperfunction, reduces ROS and superoxide production, inhibits excessive activation of A1-type astrocytes, downregulates GFAP and C3 protein expression, and restores astrocyte proliferative capacity. FGIN-1-27 produces anticonvulsant effects in normal mice; in diazepam-withdrawn mice, the brain MDR pathway becomes subsensitive, and the anticonvulsant activity disappears. FGIN-1-27 attenuates pigmentation in zebrafish embryos and ameliorates UVB-induced skin pigmentation in guinea pigs. FGIN-1-27 directly stimulates testicular Leydig cells while upregulating luteinizing hormone levels, causing an acute increase in serum testosterone in male rats. FGIN 1-27 can be used for research related to hyperpigmentation, epilepsy, brain injury, and other diseases [2] .
Cat. No.: HY-N10016
CAS No.: 132741-56-1
Target:
Cat. No.: HY-P1827
CAS No.: 219312-69-3
Target:
Domaines de recherche:
Cat. No.: HY-N0278A
CAS No.: 90921-11-2
Synonyms: (Rac)-Pulsatilla camphor; (Rac)-Anemonine
Cat. No.: HY-162714
CAS No.: 2631659-57-7
Target:
Domaines de recherche:
C3N-Dbn-Trp2 is an inhibitor for ATP-binding cassette transporter ABCB1. C3N-Dbn-Trp2 inhibits the ABCB1-mediated Rhodamine 123 (HY-D0816) efflux in cells HEK293T and HCT-15 with IC50 of 5.9 µM and 2.2 µM. C3N-Dbn-Trp2 inhibits the Doxorubicin (HY-15142A) efflux, enhances the cytotoxicity of Doxorubicin in ABCB1-expressing cells .
Cat. No.: HY-P3802
CAS No.: 100930-11-8
Target:
Domaines de recherche:
Cat. No.: HY-P81505A
Synonyms: TRP-2; TRP2; TYRP2; DCT; DT
Cat. No.: HY-P72168
Pureté: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: DCT; Dopachrome Delta-Isomerase; Prev. TYRP2; L-Dopachrome Isomerase; L-Dopachrome Tautomerase; DT; TRP-2; Dopachrome Tautomerase (Dopachrome Delta-Isomerase, Tyrosine-Related Protein 2); TRP2; Tyrosinase Related Protein-2; L-Dopachrome Delta-Isomerase; O
Species:
Human
Source:
E. coli
Cat. No.: HY-P72169
Pureté: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: DCT; Dopachrome Delta-Isomerase; Prev. TYRP2; L-Dopachrome Isomerase; L-Dopachrome Tautomerase; DT; TRP-2; Dopachrome Tautomerase (Dopachrome Delta-Isomerase, Tyrosine-Related Protein 2); TRP2; Tyrosinase Related Protein-2; L-Dopachrome Delta-Isomerase; O
Species:
Mouse
Source:
E. coli
Cat. No.: HY-101059R
CAS No.: 142720-24-9
FGIN 1-27 (Standard) is the analytical standard of FGIN 1-27 (HY-101059). This product is intended for research and analytical applications. FGIN-1-27 is a blood-brain barrier-penetrant TSPO ligand with a Ki value of 5 nM. FGIN 1-27 inhibits PKC-β, PKA/CREB, p38/ERK MAPK, MITF, tyrosinase, TRP-1, and TRP-2, thereby inhibiting melanogenesis and pigmentation. FGIN-1-27 alleviates X-ray radiation-induced astrocyte mitochondrial hyperfunction, reduces ROS and superoxide production, inhibits excessive activation of A1-type astrocytes, downregulates GFAP and C3 protein expression, and restores astrocyte proliferative capacity. FGIN-1-27 produces anticonvulsant effects in normal mice; in diazepam-withdrawn mice, the brain MDR pathway becomes subsensitive, and the anticonvulsant activity disappears. FGIN-1-27 attenuates pigmentation in zebrafish embryos and ameliorates UVB-induced skin pigmentation in guinea pigs. FGIN-1-27 directly stimulates testicular Leydig cells while upregulating luteinizing hormone levels, causing an acute increase in serum testosterone in male rats. FGIN 1-27 can be used for research related to hyperpigmentation, epilepsy, brain injury, and other diseases [2] .
Cat. No.: HY-RS03591
Target:
Domaines de recherche:
DCT Human Pre-designed siRNA Set A contains three designed siRNAs for DCT gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS11645
Target:
Domaines de recherche:
RANBP2 Human Pre-designed siRNA Set A contains three designed siRNAs for RANBP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
