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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
17 Results for "
XOD
" in MedChemExpress (MCE) Product Catalog:
Products (17)
17 Results for "XOD" in MCE Product Catalog:
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Xanthine oxidase, Microorganism (XO) is a xanthine oxidoreductase enzyme that generates reactive oxygen species (ROS), catalyzes the oxidation of hypoxanthine to xanthine, and further catalyzes the oxidation of xanthine to uric acid .
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Cat. No.: HY-141508
CAS No.: 100041-05-2
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Ketones, Aldehydes, Acids Metabolic Disease Phenols Polyphenols Endogenous metabolite Disease Research Fields
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Cat. No.: HY-116433
CAS No.: 13997-19-8
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Nequinate, a quinoline compound, is an anticoccidial agent against cecal coccidiosis (Eimeria tenella) infections . Nequinate inhibits xanthine oxidoreductase (XOD) activity .
Cat. No.: HY-175303
CAS No.: 185522-92-3
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Xanthine oxidase-IN-17 is a potent xanthine oxidase (XOD) inhibitor with an IC50 of 298 nM and a Ki of 167 nM. Xanthine oxidase-IN-17 decreases the formation of O₂ ⁻ radical by inhibiting the catalytic activity of XOD to diminish the production of uric acid. Xanthine oxidase-IN-17 shows no cytotoxicity in AML-12 hepatocytes, while suppressing uric acid production. Xanthine oxidase-IN-17 can be used for the studies of hyperuricemia and subsequently to gout .
Cat. No.: HY-116433R
CAS No.: 13997-19-8
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Nequinate (Standard) is the analytical standard of Nequinate. This product is intended for research and analytical applications. Nequinate, a quinoline compound, is an anticoccidial agent against cecal coccidiosis (Eimeria tenella) infections . Nequinate inhibits xanthine oxidoreductase (XOD) activity .
Cat. No.: HY-N14777
CAS No.: 182056-35-5
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Cat. No.: HY-N10432
CAS No.: 2571069-66-2
Synonyms: Icarisids J
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Cat. No.: HY-N10433
CAS No.: 2571069-61-7
Synonyms: Icarisids E
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Cat. No.: HY-N9324
CAS No.: 136552-23-3
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Aquifoliaceae Triterpenes Terpenoids Plants Disease Research Fields Inflammation/Immunology Tabernaemontana elegans Stapf
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Cat. No.: HY-146560
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Xanthine oxidase-IN-6 (Compound 6c) is a potent, orally active, mixed-type xanthine oxidase (XOD) inhibitor with an IC50 value of 1.37 µM. Xanthine oxidase-IN-6 shows strong anti-hyperuricemia and renal protective activity .
Cat. No.: HY-N17914
CAS No.: 935530-84-0
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Cat. No.: HY-180271
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Xanthine oxidase-IN-21, a Genipin (HY-17389) derivative, is an orally active mixed competitive xanthine oxidase (XOD) inhibitor with an IC50 of 0.68 μM. Xanthine oxidase-IN-21 reduces renal fibrosis by decreasing α-SMA expression and suppresses pro-inflammatory cytokines IL-1β, IL-6, and TNF-α through NF-κB pathway regulation. Xanthine oxidase-IN-21 also inhibits URAT1 and GLUT9 expression, promoting uric acid excretion and lowering serum uric acid levels. Xanthine oxidase-IN-21 shows significantly hepatorenal protection activity. Xanthine oxidase-IN-21 can be used for the research of hyperuricemia .
Cat. No.: HY-182000
CAS No.: 3055112-52-9
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Xanthine oxidase-IN-23 (Compound BPF) is an orally active, reversible, mixed-type Xanthine oxidase inhibitor with an IC50 of 3.33 μM. Xanthine oxidase-IN-23 directly binds to XOD in a reversible mixed-type manner to inhibit its catalytic activity. Xanthine oxidase-IN-23 upregulates ABCG2 and downregulates GLUT9 to promote renal urate excretion. Xanthine oxidase-IN-23 reduces serum urate levels and improves renal function in hyperuricemic mice. Xanthine oxidase-IN-23 can be used in the research of hyperuricemia .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
