145 Results for "

agonistic

" in MedChemExpress (MCE) Product Catalog:
Products (145)

145 Results for "agonistic" in MCE Product Catalog:

20
20 Publications Verification
Cat. No.: HY-13738A
CAS No.: 82640-04-8
Purity:  99.78%
Synonyms: Keoxifene hydrochloride; LY156758; LY139481 hydrochloride
Raloxifene hydrochloride (Keoxifene hydrochloride) is a second generation selective and orally active estrogen receptor modulator. Raloxifene hydrochloride produces estrogen-agonistic effects on bone and lipid metabolism and estrogen-antagonistic effects on uterine endometrium and breast tissue .
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20
20 Publications Verification
Cat. No.: HY-13738
CAS No.: 84449-90-1
Purity:  99.62%
Synonyms: Keoxifene; LY156758 free base; LY139481
Target:  

Estrogen Receptor/ERR

Research Areas:  

Cancer

Raloxifene (Keoxifene) is a benzothiophene-derived selective estrogen receptor modulator (SERM). Raloxifene has estrogen-agonistic effects on bone and lipids and estrogen-antagonistic effects on the breast and uterus. Raloxifene is used for breast cancer and osteoporosis research .
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4
4 Cited Publications
Cat. No.: HY-P2161B
Target:  

Kisspeptin Receptor

Research Areas:  

Cancer

TAK-683 acetate is a potent full KISS1 receptor (KISS1R) agonist (IC50=170 pM) with improved metabolic stability. TAK-683 acetate is a nonapeptide metastin analog, exhibits agonistic activities to KISS1R with EC50 values of 0.96 nM and 1.6 nM for human and rat, respectively . TAK-683 acetate depletes GnRH in the hypothalamus and reduces plasma FSH, LH, and testosterone levels in vivo, it has the potential for the study of hormone-dependent prostate cancer .
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2
2 Cited Publications
Cat. No.: HY-W013935
CAS No.: 77-40-7
Bisphenol B is a close structural analog of Bisphenol A (BPA) (HY-18260). Bisphenol B is a potent, orally active endocrine disruptor (ED). Bisphenol B binds to G protein-coupled estrogen receptor (GPER) (IC50 = 3.3 μM) with higher affinity and agonistic activity than BPA. Bisphenol B promotes GPER mediated cell migration. Bisphenol B exerts estrogenic effects via GPER pathway at nanomolar concentration. Bisphenol B is used in the manufacture of polycarbonate resin with ED properties .
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2
2 Cited Publications
Cat. No.: HY-P99123

Target:  

CD28

Research Areas:  

Inflammation/Immunology

Anti-Mouse CD28 Antibody (37.51) is an agonistic agonistic CD28-specific antibody derived from the host Syrian Hamster. Anti-Mouse CD28 Antibody (37.51) partially prevents lethal graft-versus-hostdisease (GVHD) by selective depletion of alloreactive T cells in mice .
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2
2 Cited Publications
Cat. No.: HY-119437
CAS No.: 1481401-71-1
Purity:  99.75%
Target:  

Estrogen Receptor/ERR

Research Areas:  

Cancer

FLTX1 is a fluorescent Tamoxifen derivative that can specifically label intracellular Tamoxifen-binding sites (estrogen receptors) under permeabilized and non-permeabilized conditions. FLTX1 exhibits the potent antiestrogenic properties of Tamoxifen in breast cancer cells. FLTX1 is devoid of the estrogenic agonistic effect on the uterus .
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1
1 Cited Publications
Cat. No.: HY-103698A
CAS No.: 1620278-72-9
Purity:  99.70%
Research Areas:  

Inflammation/Immunology

TLR7/8 agonist 1 dihydrochloride is a toll-like receptor TLR7/TLR8 dual-agonistic imidazoquinoline .
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1
1 Cited Publications
Cat. No.: HY-103698
CAS No.: 1258457-59-8
Purity:  98.42%
Research Areas:  

Inflammation/Immunology

TLR7/8 agonist 1 is a toll-like receptor (TLR7)/TLR8 dual-agonistic imidazoquinoline.
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1
1 Cited Publications
Cat. No.: HY-N1426
CAS No.: 5471-51-2
Synonyms: Frambione; 4-(4-Hydroxyphenyl)-2-butanone
Raspberry ketone is a major aromatic compound of red raspberry, widely used as a fragrance in cosmetics and as a flavoring agent in foodstuff; also shows PPAR-α agonistic activity.
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1
1 Cited Publications
Cat. No.: HY-12397
CAS No.: 156965-15-0
Purity:  99.23%
Target:  

VD/VDR

Research Areas:  

Endocrinology

ZK159222, a 25-carboxylic ester analogue of 1α,25-(OH)2D3, is a potent 1α,25-(OH)2D3 receptor (VDR) antagonist. The mechanism of ZK159222 antagonistic action is mediated by a lack of ligand-induced vitamin D receptor interaction with coactivators. ZK159222 has a partial agonistic character .
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1
1 Cited Publications
Cat. No.: HY-P990680
Anti-Mouse CD40 Antibody (FGK4.5/FGK45) is an agonistic rat-derived IgG2a monoclonal antibody targeting mouse CD40. Anti-Mouse CD40 Antibody (FGK4.5/FGK45) enhances T cells responses, dendritic cells maturation and NK cells activation. Anti-Mouse CD40 Antibody (FGK4.5/FGK45) can be used for the researches of cancer, infection, inflammation and immunology, such as CT26 tumor, vesicular stomatitis virus (VSV) infection and transplantation .
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Cat. No.: HY-123012
CAS No.: 391920-32-4
Purity:  98.40%
Synonyms: LY-488756
Target:  

Adrenergic Receptor

Research Areas:  

Others

Lubabegron is a potent modulator of β-adrenergic receptor (β-AR). Lubabegron demonstrates antagonistic behavior at the β1 and β 2 receptor subtypes and agonistic behavior at the β 3 receptor subtype in cattle. Lubabegron reduces NH3 gas emissions from an animal or its waste. Lubabegron is available as an animal supplement .
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Cat. No.: HY-P99049
CAS No.: 2305607-45-6
Synonyms: APX005M; APX005M; EPI-0050

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology Cancer

Sotigalimab, a CD40 agonistic monoclonal antibody. Sotigalimab binds CD40 with high affinity and activates antigen-presenting cells, thereby stimulating cancer-specific T cell responses. Sotigalimab is mainly used in the study of metastatic pancreatic cancer and metastatic melanoma .
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Cat. No.: HY-P99286
CAS No.: 912628-39-8
Synonyms: PRO 95780; rhuMAb-DR 5; Anti-Human DR5 Recombinant Antibody

Target:  

Apoptosis

Research Areas:  

Cancer

Drozitumab (PRO 95780) is a human agonistic monoclonal antibody which binds the death receptor DR5. Drozitumab has potent antitumor activity against rhabdomyosarcoma .
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Cat. No.: HY-P99299
CAS No.: 845816-02-6
Synonyms: HGS-ETR 2; ETR2-ST01

Target:  

Apoptosis

Research Areas:  

Cancer

Lexatumumab (HGS-ETR 2) is a human agonistic TRAIL receptor 2 (TRAIL-R2, DR5, APO-2) IgG4κ type monoclonal antibody. Lexatumumab induces apoptosis in malignant mesothelioma. Lexatumumab can be used for malignant pleural mesothelioma (MPM) research .
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Cat. No.: HY-P990155
Anti-Mouse TIGIT Antibody (1G9) is a mouse-derived agonistic TIGIT IgG1 κ type antibody. Anti-Mouse TIGIT Antibody (1G9) blocks CD155 binding to TIGIT. Anti-Mouse TIGIT Antibody (1G9) shows potent anti-infection and anti-immune effects in septic and experimental autoimmune encephalomyelitis .
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Cat. No.: HY-P99470
CAS No.: 2109730-69-8
Synonyms: GEN1029

Target:  

TNF Receptor Apoptosis

Research Areas:  

Cancer

Benufutamab (GEN1029) is a death receptor 5 (DR5)-specific agonistic antibody. Benufutamab is a mixture of 2 noncompeting DR5-specific IgG1 antibodies, each with an E430G mutation in the Fc domain. Benufutamab has antitumor effects .
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Cat. No.: HY-P99378
CAS No.: 2158362-38-8
Synonyms: ALTB-168; Anti-PSGL1/CD162 Reference Antibody (neihulizumab); AbGn-168

Target:  

Apoptosis

Research Areas:  

Inflammation/Immunology

Neihulizumab (ALTB-168) is an immune checkpoint agonistic antibody that binds to human CD162 (PSGL-1), leading to downregulation of activated T-cells. Neihulizumab can be uesd for steroid-refractory acute graft-versus-host-disease (SR-aGVHD), psoriasis, psoriatic arthritis and ulcerative colitis research .
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Cat. No.: HY-P99265
CAS No.: 658052-09-6
Synonyms: HGS-ETR1; Anti-Human TNFRSF10A Recombinant Antibody

Target:  

Inhibitory Antibodies

Research Areas:  

Cancer

Mapatumumab (HGS-ETR1) is a fully human IgG1 agonistic monoclonal antibody that targets tumor necrosis factor-related apoptosis-inducing ligand receptor 1 (TRAIL-R1). Mapatumumab can be used for the research of cancer .
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Cat. No.: HY-108608
CAS No.: 313981-55-4
Purity:  99.88%
Target:  

Calcium Channel

Research Areas:  

Others

o-3M3FBS is the negative control of m-3M3FBS. o-3M3FBS inhibits inward and outward currents via mechanisms independent of PLC acting in an antagonistic manner. In contrast, o-3M3FBS also causes an increase in [Ca 2+]i in an agonistic manner .
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