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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
anticodon
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "anticodon" in MCE Product Catalog:
3
3 Cited Publications
Synonyms: N1-Methylinosine
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Disease Research Antibacterial Biological Pesticide Research Other Antibiotics Agricultural Research Plant agriculture research Infection Antibiotics Resistance Selection Microorganism Disease Research Fields
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Kasugamycin (Ksg) hydrochloride hydrate is an aminoglycoside antibiotic (antibiotic) that binds to the bacterial 30S ribosomal subunit and inhibits canonical translation initiation. Kasugamycin hydrochloride hydrate binds to the P-site and E-site codon regions in the mRNA channel and interferes with mRNA-tRNA codon-anticodon interactions, thereby destabilizing initiator tRNA binding. Kasugamycin hydrochloride hydrate possesses anti-infective activity. Kasugamycin hydrochloride hydrate is used in research on bacterial translation and Pseudomonas infection .
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Kasugamycin (Ksg) is an aminoglycoside antibiotic (antibiotic) that binds to the bacterial 30S ribosomal subunit and inhibits canonical translation initiation. Kasugamycin binds to the P-site and E-site codon regions in the mRNA channel and interferes with mRNA-tRNA codon-anticodon interactions, thereby destabilizing initiator tRNA binding. Kasugamycin possesses anti-infective activity. Kasugamycin is used in research on bacterial translation and Pseudomonas infection .
Cat. No.: HY-113139S
Purity: ≥99.0%
Synonyms: N1-Methylinosine-d3
Cat. No.: HY-131481
CAS No.: 32860-54-1
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Cat. No.: HY-B1864C
CAS No.: 78822-08-9
Synonyms: Ksg sulfate
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Kasugamycin (Ksg) sulfate is an aminoglycoside antibiotic (antibiotic) that binds to the bacterial 30S ribosomal subunit and inhibits canonical translation initiation. Kasugamycin sulfate binds to the P-site and E-site codon regions in the mRNA channel and interferes with mRNA-tRNA codon-anticodon interactions, thereby destabilizing initiator tRNA binding. Kasugamycin sulfate possesses anti-infective activity. Kasugamycin sulfate is used in research on bacterial translation and Pseudomonas infection .
Cat. No.: HY-169810
CAS No.: 849658-87-3
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PKZ18 is an antibiotic and inhibits bacterial growth, with MIC values of 32-64 μg/mL against most Gram-positive bacteria. PKZ18 inhibits in vivo transcription and translation of glycyl-tRNA synthetase mRNA. PKZ18 selectively targets stem I specifier loops in Gram-positive bacteria and directly reduces T-box transcriptional read-through of the associated genes. PKZ18 prevents the codon-anticodon reading required for tRNA binding and is refractory to resistance .
Cat. No.: HY-B1864AR
CAS No.: 19408-46-9
Synonyms: Ksg hydrochloride (Standard)
Category:
Antibiotics Resistance Selection Microorganism Disease Research Antibacterial Other Antibiotics Plant agriculture research
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Cat. No.: HY-B1864BR
CAS No.: 200132-83-8
Synonyms: Ksg hydrochloride hydrate (Standard)
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Kasugamycin hydrochloride hydrate (Standard) (Ksg hydrochloride hydrate (Standard)) is the analytical standard of Kasugamycin hydrochloride hydrate (HY-B1864B). This product is intended for research and analytical applications. Kasugamycin (Ksg) hydrochloride hydrate is an aminoglycoside antibiotic (antibiotic) that binds to the bacterial 30S ribosomal subunit and inhibits canonical translation initiation. Kasugamycin hydrochloride hydrate binds to the P-site and E-site codon regions in the mRNA channel and interferes with mRNA-tRNA codon-anticodon interactions, thereby destabilizing initiator tRNA binding. Kasugamycin hydrochloride hydrate possesses anti-infective activity. Kasugamycin hydrochloride hydrate is used in research on bacterial translation and Pseudomonas infection .
Cat. No.: HY-182338
CAS No.: 31281-28-4
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2'-Thiouridine is a key modified nucleoside at the wobble position of tRNA anticodons. 2'-Thiouridine mainly exists in tRNAs for glutamic acid, glutamine, lysine, etc., and participates in precise decoding regulation .
Cat. No.: HY-149193
CAS No.: 497258-53-4
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5-Taurinomethyluridine is a taurine-containing modified uridine and translation regulator that exists in Trp and Leu (UUR) tRNAs of mammalian mitochondria. 5-Taurinomethyluridine is located at the first position of the anticodon of these mitochondrial tRNAs. 5-Taurinomethyluridine is synthesized from taurine and one-carbon metabolites by GTPBP3/MTO1, and its deficiency directly causes abnormal mitochondrial translation and various human mitochondrial diseases .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
