2628 Results for "

antigen

" in MedChemExpress (MCE) Product Catalog:
Products (2628)

2628 Results for "antigen" in MCE Product Catalog:

582
582 Publications Verification
製品番号: HY-D1056
別名: LPS, from Escherichia coli (O55:B5)
Lipopolysaccharides, from E. coli O55:B5 (LPS, from Escherichia coli (O55:B5)) are endotoxins and TLR4 activators extracted from Escherichia coli (E. coli O55:B5) and are classified as S (smooth) type LPS. Lipopolysaccharides, from E. coli O55:B5 possess the typical three-part structure: O-antigen, core oligosaccharide, and lipid A. Lipopolysaccharides, from E. coli O55:B5 activate TLR-4 in immune cells, exhibit high pyrogenicity, and demonstrate dose and serotype specificity. Lipopolysaccharides, from E. coli O55:B5 can be widely used to induce cellular inflammation and establish animal models related to inflammation .
It is recommended to prepare a solution with concentration ≥2 mg/mL. Vortex thoroughly for more than 10 minutes. Due to the adsorption characteristics of LPS, silanized container or low adsorption centrifuge tubes should be used for aliquoting and storage, and mix thoroughly before use.
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36
36 Cited Publications
製品番号: HY-19989
CAS 番号: 115104-28-4
別名: L-660711
MK-571 (L-660711) is an orally active, potent and selective competitive leukotriene D4 (LTD4) receptor antagonist, with Ki values of 0.22 and 2.1 nM in guinea pig and human lung membranes, respectively. MK-571 is also a MRP4 and ABCC1 (MRP1) inhibitor. MK-571 inhibits constitutive and antigen-stimulated S1P (sphingosine-1-phosphate) release .
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36
36 Cited Publications
製品番号: HY-19989A
CAS 番号: 115103-85-0
別名: L-660711 sodium
MK-571 (L-660711) sodium is an orally active, potent and selective competitive leukotriene D4 (LTD4) receptor antagonist, with Ki values of 0.22 and 2.1 nM in guinea pig and human lung membranes, respectively. MK-571 sodium is also a inhibitor of multidrug resistance-associated protein MRP4 (ABCC4) and ABCC1 (MRP1). MK-571 sodium inhibits constitutive and antigen-stimulated S1P (sphingosine-1-phosphate) release .
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31
31 Cited Publications
製品番号: HY-K2005

High Sensitivity ECL Kit enables low picogram detection of antigen by oxidizing luminol in the presence of HRP and peroxide. This reaction produces a prolonged chemiluminescence which can be visualized on X-ray film or digital imaging systems. The 100 mL is defined as the base specification. All larger sizes correspond to incremental volumes of this base.

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27
27 Cited Publications
製品番号: HY-110385
CAS 番号: 2407516-83-8
純度:  98.47%
別名: Cyclic GMP-AMP disodium; 3',3'-cGAMP disodium
cGAMP (Cyclic GMP-AMP) disodium functions as an endogenous second messenger in metazoans and triggers interferon production in response to cytosolic DNA. cGAMP diammonium activates stimulator of interferon genes (STING), which activates a signaling cascade leading to the production of type I interferons and other immune mediators .
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27
27 Cited Publications
製品番号: HY-110385A
純度:  95.19%
別名: Cyclic GMP-AMP diammonium; 3',3'-cGAMP diammonium
cGAMP (Cyclic GMP-AMP) diammonium functions as an endogenous second messenger in metazoans and triggers interferon production in response to cytosolic DNA. cGAMP diammonium activates stimulator of interferon genes (STING), which activates a signaling cascade leading to the production of type I interferons and other immune mediators .
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27
27 Cited Publications
製品番号: HY-12512
CAS 番号: 849214-04-6
純度:  98.28%
別名: Cyclic GMP-AMP; 3',3'-cGAMP
Target:  

STING

研究分野:  

Inflammation/Immunology

cGAMP (Cyclic GMP-AMP) functions as an endogenous second messenger in metazoans and triggers interferon production in response to cytosolic DNA. cGAMP activates stimulator of interferon genes (STING), which activates a signaling cascade leading to the production of type I interferons and other immune mediators .
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22
22 Cited Publications
製品番号: HY-153808
CAS 番号: 9007-81-2
研究分野:  

Inflammation/Immunology

Complete Freund's adjuvant (CFA) is an immunoadjuvant emulsified with antigen by its discoverer Jules T. Freund to enhance an animal's immune response to an antigen. Complete Freund's adjuvant (CFA) is also an inducer of the Th1 immune response and a ligand of TLRs. Complete Freund's adjuvant (CFA) contains heat-killed inactive tuberculosis bacilli and consists of a paraffin oil-in-water emulsion. Complete Freund's adjuvant (CFA) stimulates a strong and durable immune response and can be used to induce persistent inflammatory pain models in mice, experimental autoimmune myocarditis (EAM) models, and more. Incomplete Freund's adjuvant (IFA) (HY-153808A) is another type of Freund's Adjuvant that stimulates a weaker immune response .
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19
19 Cited Publications
製品番号: HY-P1439
CAS 番号: 1449566-36-2
RS 09 is an LPS (HY-D1056) peptide mimic and TLR4 agonist. RS 09 can bind to TLR-4 and activate NF-κB. RS 09 can function as an adjuvant in vivo, enhancing the antigen-specific immune response .
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19
19 Cited Publications
製品番号: HY-P1439A
RS 09 TFA is an LPS (HY-D1056) peptide mimic and TLR4 agonist. RS 09 TFA can bind to TLR-4 and activate NF-κB. RS 09 TFA can function as an adjuvant in vivo, enhancing the antigen-specific immune response .
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17
17 Cited Publications
製品番号: HY-117410
CAS 番号: 1702967-37-0
純度:  99.46%
別名: PSMA-617
研究分野:  

Cancer

Vipivotide tetraxetan (PSMA-617) is a high potent prostate-specific membrane antigen (PSMA) inhibitor, with a Ki of 0.37 nM. Vipivotide tetraxetan (PSMA-617) is designed consisting of three components: the pharmacophore Glutamate-urea-Lysine, the chelator DOTA able to complex both 68Ga or 177Lu, and a linker connecting these two entities. Glutamate-urea-Lysine is the selective pharmacophore to bind to prostate specific membrane antigen.
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12
12 Cited Publications
製品番号: HY-P70527
純度:  ≥ 95%, as determined by reducing SDS-PAGE.
別名: Interleukin-17A; IL-17; IL-17A; Cytotoxic T-Lymphocyte-Associated antigen 8; CTLA-8; IL17A; CTLA8; IL17
Species:  
Source:  
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11
11 Cited Publications
製品番号: HY-19344
CAS 番号: 1025967-78-5
別名: SAR 1118; SHP-606
Target:  

Integrin

研究分野:  

Inflammation/Immunology

Lifitegrast (SAR 1118) is a potent integrin antagonist. Lifitegrast blocks the binding of intercellular adhesion molecule 1 (ICAM-1) to lymphocyte function-associated antigen 1 (LFA-1), interrupting the T cell-mediated inflammatory cycle. Lifitegrast inhibits Jurkat T cell attachment to ICAM-1 with an IC50 of 2.98 nM. Lifitegrast can be used for researching dry eye disease .
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11
11 Cited Publications
製品番号: HY-19344A
CAS 番号: 1119276-80-0
別名: SAR 1118 sodium; SHP-606 sodium
Target:  

Integrin

研究分野:  

Inflammation/Immunology

Lifitegrast (SAR 1118) sodium is a potent integrin antagonist. Lifitegrast sodium blocks the binding of intercellular adhesion molecule 1 (ICAM-1) to lymphocyte function-associated antigen 1 (LFA-1), interrupting the T cell-mediated inflammatory cycle. Lifitegrast sodium inhibits Jurkat T cell attachment to ICAM-1 with an IC50 of 2.98 nM. Lifitegrast sodium can be used for researching dry eye disease .
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10
10 Cited Publications
製品番号: HY-109506
CAS 番号: 63-89-8
純度:  99.91%
別名: 129Y83
DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes. DPPC is the main lipid component of pulmonary surfactant. Dppc-liposome can be effectively used as a delivery vector to induce an immune response against GSL antigen in mice .
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10
10 Cited Publications
製品番号: HY-117650A
CAS 番号: 2072057-17-9
純度:  99.85%
別名: RO 7020322; (S)-RO0321
Target:  

HBV

研究分野:  

Infection

RG7834 (RO 7020322) is a highly selective and orally bioavailable HBV inhibitor, potently inhibits HBV antigens (both HBsAg and HBeAg) and HBV DNA, with IC50s of 2.8, 2.6, and 3.2 nM, respectively, in dHepaRG Cells .
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9
9 Cited Publications
製品番号: HY-112758
CAS 番号: 1190197-97-7
純度:  99.88%
DLin-KC2-DMA is an ionisable cationic lipid (pKa≈6) that is virtually non-toxic to antigen presenting cells (APCs). DLin-KC2-DMA produces significant siRNA-mediated gene silencing of GAPDH, when binds to lipid nanoparticles (LNP). DLin-KC2-DMA can be used in siRNA delivery studies .
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9
9 Cited Publications
製品番号: HY-P99045
CAS 番号: 1796566-95-4
別名: HRS7; hRS7

Target:  

ADC Antibodies TROP2

研究分野:  

Cancer

Sacituzumab is a humanized IgG1 monoclonal antibody targeting Trophoblast cell surface antigen 2 (TROP2). Sacituzumab demonstrates a lack of antitumor effects alone and does not inhibit the function of TROP-2 during tumor metastasis, binding to the linear epitopes of TROP-2 protein. Sacituzumab can be used for the synthesis of antibody-drug conjugates (ADC) drug Sacituzumab govitecan (HY-132254). Sacituzumab govitecan can be used in the field of triple-negative breast cancer .
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9
9 Cited Publications
製品番号: HY-153808A
Target:  

Bacterial

研究分野:  

Inflammation/Immunology Cancer

Incomplete Freund's adjuvant (IFA) (Montanide ISA-51) is an immunoadjuvant emulsified with antigen by its discoverer Jules T. Freund. Incomplete Freund's adjuvant (IFA) does not contain inactivated tuberculosis bacilli and consists of petroleum jelly containing lanolin. Incomplete Freund's adjuvant (IFA) induces high antibody titers and long-lasting effector T cell responses with no long-term effects on collagen disease, tumors, or death. Complete Freund's adjuvant (CFA) (HY-153808) is another type of Freund's Adjuvant that stimulates a stronger immune response .
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8
8 Cited Publications
製品番号: HY-K2006

Sensitive ECL Kit enables low picogram detection of antigen by oxidizing luminol in the presence of HRP and peroxide. This reaction produces a prolonged chemiluminescence which can be visualized on X-ray film or digital imaging systems. The 100 mL is defined as the base specification. All larger sizes correspond to incremental volumes of this base.

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