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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
54 Results for "
brain-derived
" in MedChemExpress (MCE) Product Catalog:
Products (54)
54 Results for "brain-derived" in MCE Product Catalog:
21
21 Publications Verification
Cat. No.: HY-W013372
CAS No.: 38183-03-8
Category:
Flavonoids Umbelliferae Extract Flavones Phenols Polyphenols Plants Carphephorus corymbosus (Nutt.) Torr. & A.Gray
Target:
15
15 Cited Publications
Cat. No.: HY-P7116A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: BDNF; Abrineurin; brain derived Neurotrophic Factor; brain-derived Neurotrophic Factor Preproprotein Isoform 2; ProBDNF; brain-derived Neurotrophic Factor Isoform 1; Neurotrophic Factor BDNF Precursor Form; ANON2; brain-derived Neurotrophic Factor; BULN2
Species:
Mouse
Rat
Human
Source:
E. coli
5
5 Cited Publications
Target:
Research Areas:
PI3K/Akt/CREB activator 1 (compound AE-18) is a potent, orally active PI3K/Akt/CREB activator. PI3K/Akt/CREB activator 1 promotes neuronal proliferation, induced differentiation of Neuro-2a cells into a neuron-like morphology, and accelerated the establishment of axon-dendrite polarization of primary hippocampal neurons through upregulating brain-derived neurotrophic factor via the PI3K/Akt/CREB pathway. PI3K/Akt/CREB activator 1 can be used in research of vascular dementia (VaD) .
3
3 Cited Publications
Cat. No.: HY-P74383
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: BDNF; Abrineurin; brain derived Neurotrophic Factor; brain-derived Neurotrophic Factor Preproprotein Isoform 2; ProBDNF; brain-derived Neurotrophic Factor Isoform 1; Neurotrophic Factor BDNF Precursor Form; ANON2; brain-derived Neurotrophic Factor; BULN2
Species:
Mouse
Source:
HEK293
1
Category:
Geraniaceae Extract Pelargonium hortorum Bailey Neurological Disease Anemarrhena asphodeloides Bunge Plants Liliaceae Extract Disease Research Fields Steroids
Target:
1
1
1 Cited Publications
Cat. No.: HY-P700158AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: BDNF; Abrineurin; brain derived Neurotrophic Factor; brain-derived Neurotrophic Factor Preproprotein Isoform 2; ProBDNF; brain-derived Neurotrophic Factor Isoform 1; Neurotrophic Factor BDNF Precursor Form; ANON2; brain-derived Neurotrophic Factor; BULN2
Species:
Rat
Mouse
Human
Source:
E. coli
1
Target:
Research Areas:
TC-2153 is a selective inhibitor of striatal-enriched protein tyrosine phosphatase (STEP), with psychotropic activity and low acute toxicity. TC-2153 increases the expression of brain-derived neurotropic factor (BDNF) in the brain. And it decreases MAOA and 5-HT1A receptors mRNA level in midbrain. TC-2153 also inhibits 5-HT2A receptor-mediated signaling .
Cat. No.: HY-N2055
CAS No.: 19895-95-5
Target:
Synonyms: NSI-189
Target:
Research Areas:
Amdiglurax (NSI-189) is an orally active chemical entity with enhanced neurogenic activity. Amdiglurax up-regulates neurogenic factors such as BDNF (brain derived-neurotrophic factor) and SCF. Amdiglurax exhibits anti-depressant effect. Amdiglurax enhances synaptic plasticity and reduces cognitive dysfunction. Amdiglurax holds potential for psychiatric disorder research .
Cat. No.: HY-P3601
CAS No.: 211362-85-5
Synonyms: FGF basic (1-24)
Research Areas:
Target:
Research Areas:
HBT1 is an effective AMPA receptor AMPA-R potentiator. HBT1 specifically binds to the ligand-binding domain (LBD) of AMPAR and enhances receptor activity only when AMPA is present., HBT1 has almost no agonistic effect (i.e., reaching the optimal concentration, and then the efficacy decreases as the concentration continues to increase) compared with traditional AMPA-R potentiator, avoiding the bell-shaped reaction of brain-derived neurotrophic factor (BDNF) production in primary neurons. HBT1 can be applicable to a wider range of neurological and psychiatric diseases (such as depression, Alzheimer's disease, etc.) .
Cat. No.: HY-N3298
CAS No.: 23971-42-8
Synonyms: NSI-189 phosphate
Target:
Research Areas:
Amdiglurax (NSI-189) phosphate is an orally active chemical entity with enhanced neurogenic activity. Amdiglurax phosphate up-regulates neurogenic factors such as BDNF (brain derived-neurotrophic factor) and SCF. Amdiglurax phosphate exhibits anti-depressant effect. Amdiglurax enhances synaptic plasticity and reduces cognitive dysfunction. Amdiglurax phosphate holds potential for psychiatric disorder research .
Cat. No.: HY-P3587
CAS No.: 211362-82-2
Target:
Research Areas:
Cat. No.: HY-W013372R
CAS No.: 38183-03-8
Category:
Flavonoids Umbelliferae Extract Flavones Phenols Polyphenols Plants Carphephorus corymbosus (Nutt.) Torr. & A.Gray
Target:
Target:
Research Areas:
BNN-20 is a synthetic microneurotrophin that mimics brain-derived neurotrophic factor (BDNF) and exhibits area-specific pleiotropic neuroprotective and pro-neurogenic effects. BNN-20 can be utilized in research related to Parkinson's disease .
Cat. No.: HY-E70870
Target:
Research Areas:
TRKB(NTRK2) is a member of tyrosine kinase gene family. TRKB is the primary receptor for brain-derived nerve growth factor (BDNF) and neurotrophin 4/5 (NT4/5). TRKB(NTRK2) Recombinant Human Active Protein Kinase is a recombinant TRKB(NTRK2) protein that can be used to study TRKB(NTRK2)-related functions .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
