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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
27 Results for "
cellular metabolic processes
" in MedChemExpress (MCE) Product Catalog:
Products (27)
27 Results for "cellular metabolic processes" in MCE Product Catalog:
7
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NADP sodium salt is the sodium salt form of NADP (HY-113325). NADP is a coenzyme involved in cellular electron transfer reactions in biological metabolism, which is alternately oxidized (NADP+) and reduced (NADPH), and can maintain cellular redox homeostasis and regulate many biological events, including cellular metabolism. NADPH is a universal electron donor that provides reducing ability for synthetic metabolic reactions and redox balance. NADPH plays a multifunctional role in regulating inflammation, redox homeostasis, and synthetic metabolism processes .
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other families Microorganisms Animals Ketones, Aldehydes, Acids Other Diseases Plants Disease Research Fields
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7
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Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields
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7 Publications Verification
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Cat. No.: HY-121970
CAS No.: 27031-00-1
Target:
Phosphoglycerate Dehydrogenase (PHGDH) Reactive Oxygen Species (ROS) HIF/HIF Prolyl-Hydroxylase
Research Areas:
iGP-1 is a cell-permeable, selective mixed inhibitor of mitochondrial sn-glycerol-3-phosphate dehydrogenase (mGPDH), with IC50s of 6.3 μM and 13.6 μM for rat mGPDH activity and H2O2 production, respectively. iGP-1 specifically blocks the mitochondrial component of the glycerophosphate shuttle without affecting cytosolic GPDH. iGP-1 not only inhibits cell proliferation and glutaminolysis, and enhances glycolysis, but also significantly alters key cellular physiological processes such as apoptosis, ROS production, HIF-1α stability and mitochondrial membrane potential. iGP-1 remains active in neutrophil cultures under both normoxic and hypoxic conditions, and serves as an ideal probe for glycerol-3-phosphate metabolic mechanisms. iGP-1 has been applied to studies on prostate cancer and related metabolic pathways .
Cat. No.: HY-143212
CAS No.: 65886-80-8
Synonyms: 1-Stearoyl-2-docosahexaenoyl-sn-glycerol
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MS6105 is a PROTAC degrader targeting LDHA and LDHB, with DC50 values of 38 nM and 74 nM for degrading LDHA and LDHB in PANC-1 cells, respectively, and no hook effect is observed at high concentrations. MS6105 inhibits the proliferation of pancreatic cancer cells, and no obvious toxicity is observed after intraperitoneal administration in mice. MS6105 can be used for pancreatic cancer-related research .
Cat. No.: HY-113325AR
CAS No.: 698999-85-8
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NADP (sodium salt) (Standard) is the analytical standard of NADP (sodium salt). This product is intended for research and analytical applications. NADP sodium salt is the sodium salt form of NADP (HY-113325). NADP is a coenzyme involved in cellular electron transfer reactions in biological metabolism, which is alternately oxidized (NADP+) and reduced (NADPH), and can maintain cellular redox homeostasis and regulate many biological events, including cellular metabolism. NADPH is a universal electron donor that provides reducing ability for synthetic metabolic reactions and redox balance. NADPH plays a multifunctional role in regulating inflammation, redox homeostasis, and synthetic metabolism processes[1][4].
Cat. No.: HY-113225S2
Synonyms: GTP-13C dilithium
Cat. No.: HY-113225S3
Purity: ≥95.0%
Synonyms: GTP-15N5 dilithium
Cat. No.: HY-113225S5
Purity: ≥95.0%
Synonyms: GTP-13C10 dilithium
Cat. No.: HY-113225S1
Synonyms: GTP-13C10,15N5 tetraammonium
Cat. No.: HY-113225S4
Purity: 98.4%
Synonyms: GTP-15N5,d14 dilithium
Cat. No.: HY-W925660
CAS No.: 20226-99-7
(+)-Potassium Ds-threo-isocitrate monobasic is a biologically active compound that has the activity of promoting cellular metabolism and regulating energy production. (+)-Potassium Ds-threo-isocitrate monobasic can also be used to study the regulation of metabolic pathways and enzyme activities. (+)-Potassium Ds-threo-isocitrate monobasic is widely used in biochemical research to explore its potential role in cellular function and disease processes.
Cat. No.: HY-F0002AR
CAS No.: 24292-60-2
Synonyms: Disodium NADP (Standard)
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
