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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
64 Results for "
complexation property
" in MedChemExpress (MCE) Product Catalog:
Products (64)
64 Results for "complexation property" in MCE Product Catalog:
107
107 Publications Verification
Synonyms: FK506; Fujimycin; FR900506
107
107 Publications Verification
Synonyms: FK506 monohydrate; Fujimycin monohydrate; FR900506 monohydrate
27
Áreas de investigación:
Thalidomide inhibits cereblon (CRBN), a part of the cullin-4 E3 ubiquitin ligase complex CUL4-RBX1-DDB1, with a Kd of ∼250 nM, and has immunomodulatory, anti-inflammatory and anti-angiogenic cancer properties. Thalidomide can work as molecular glue to potentiate substrate.
6
6 Cited Publications
Target:
Áreas de investigación:
MnTBAP chloride is a superoxide dismutase (SOD) mimetic and peroxynitrite scavenger. MnTBAP chloride is a manganic porphyrin complex and has anti-oxidative property. MnTBAP chloride mediates anti-inflammatory effects through upregulation of BMPR-II and inhibition of the NFκB signaling. MnTBAP chloride has the potential for the fibrotic response in chronic kidney diseases (CKDs) research .
2
Áreas de investigación:
Bacitracin Zinc is a complex formed by the binding of Bacitracin (HY-107193) with zinc ions. Bacitracin Zinc is an orally active polypeptide antibiotic with bactericidal properties. Bacitracin Zinc can cause DNA and deoxyribose damage, as well as improve the gut microbiota of broiler and beef cattle .
1
1 Cited Publications
Synonyms: FK506-13C,d2; Fujimycin-13C,d2; FR900506-13C,d2
1
1 Cited Publications
Referencia número: HY-W127832
No. CAS: 123148-15-2
Referencia número: HY-D1247
No. CAS: 63451-35-4
Hydroxynaphthol Blue is an azo dye and serves as a metal indicator. Hydroxynaphthol Blue binds to specific metal ions to form stable complexes with distinct color and fluorescence properties. Hydroxynaphthol Blue is used for the visual monitoring of isothermal nucleic acid amplification results. A visible color difference appears between positive and negative nucleic acid amplification reactions, allowing result discrimination by the naked eye without opening the reaction tube .
OF-02 is an ionizable lipid for mRNA delivery and a key component of lipid nanoparticles (LNPs). OF-02 is protonated in the acidic endosomal environment to promote endosomal escape of mRNA and efficiently induce protein expression in target cells. OF-02 relies on the pH-responsive membrane fusion properties to form a complex with mRNA and destroy the endosomal membrane structure to achieve mRNA release in the cytoplasm. OF-02 is mainly used in the development of mRNA vaccines, gene editing, and protein replacement therapy[1][2][3].
0 Images
Defibrotide (sodium)
Referencia número: HY-108746
No. CAS: 83712-60-1
Synonyms: Vimdemer
Referencia número: HY-13756R
No. CAS: 104987-11-3
Synonyms: FK506 (Standard); Fujimycin (Standard); FR900506 (Standard)
Referencia número: HY-P99638
No. CAS: 2456407-94-4
Synonyms: ALXN-1720
Target:
Áreas de investigación:
Target:
Áreas de investigación:
Acedoben is a biochemical reagent. Acedoben can form a rapidly self-assembled coordination complex with iron ions. The Fe-Ace coordination complex not only serves as a carrier for tumor antigens, but also enhances antigen-specific anti-tumor immunity due to its inherent adjuvant properties .
Referencia número: HY-W127820
No. CAS: 129051-18-9
Synonyms: Tetrakis(2-N-methylpyridyl)porphine chloride
Áreas de investigación:
H2TMpyP-2 (tetrakis(2-N-methylpyridyl)porphine) chloride is an active photosensitizer with strong absorption properties in the visible to near-infrared region and excellent singlet oxygen quantum yield. Captisol-TMPyP complexes can be used in supramolecular nanosynthesis to increase singlet oxygen production, improve photostability and better photosensitization, and support photodynamic therapy activity. The Captisol:TMPyP complex also exhibited antibacterial activity against Escherichia coli and was cytotoxic against lung cancer A549 cells .
Áreas de investigación:
Thalidomide (Standard) is the analytical standard of Thalidomide. This product is intended for research and analytical applications. Thalidomide inhibits cereblon (CRBN), a part of the cullin-4 E3 ubiquitin ligase complex CUL4-RBX1-DDB1, with a Kd of ∼250 nM, and has immunomodulatory, anti-inflammatory and anti-angiogenic cancer properties. Thalidomide can work as molecular glue to potentiate substrate.
Referencia número: HY-13756S2
Synonyms: FK506-d3; Fujimycin-d3; FR900506-d3
Referencia número: HY-W035133
No. CAS: 14527-51-6
Synonyms: 5,10,15,20-Tetra-p-tolyl-21H,23H-porphine
Referencia número: HY-158405
No. CAS: 2923674-83-1
Synonyms: MAV-104
Target:
Áreas de investigación:
PAV-104 (MAV-104) is a host-targeted, pan-respiratory viral assembly inhibitor. PAV-104 targets a small subset of the host protein 14-3-3 within a transient multi-protein complex. PAV-104 inhibits SARS-CoV-2 replication by blocking post-entry viral assembly/budding through interaction with viral nucleocapsid (N) protein and interference with its oligomerization. PAV-104 is orally active in cats and shows favorable pharmacokinetic properties in rats. PAV-104 can be used for the study of COVID-19 and other respiratory viral infections, including Feline Infectious Peritonitis (FIP) .
Referencia número: HY-W014159
No. CAS: 55289-35-5
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
