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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
30 Results for "
correlation
" in MedChemExpress (MCE) Product Catalog:
Products (30)
30 Results for "correlation" in MCE Product Catalog:
1
1 Cited Publications
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PROTAC MLKL Degrader-1 is a selective MLKL PROTAC degrader with a DC50 of 2.4 μM. PROTAC MLKL Degrader-1 blocks necroptosis without modulating the phosphorylation of RIPK1 or RIPK3, and exhibits a linear correlation between MLKL levels and necroptotic cell death .
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Toloxatone (MD 69276) is a reversible, selective MAO-A inhibitor that can cross the blood-brain barrier. Toloxatone increases the levels of serotonin (5-HT) and norepinephrine in the brain. Toloxatone reduces the immobility time in the forced swimming test in mice, inhibits killing behavior in rats without causing sedation, and shows a correlation between its free plasma concentration and cerebrospinal fluid concentration. Toloxatone is widely used in research related to depression, depressive disorders and Parkinson's disease .
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dCeMM4 is a Cyclin K Molecular glue degrader. dCeMM4 mediates the direct interaction between CDK12:cyclin K and the CRL4B ligase complex, thereby driving the ubiquitination and proteasomal degradation of Cyclin K. dCeMM4 induces Apoptosis without cell cycle phase-specific arrest. dCeMM4 exhibits synergistic activity with DNA damage inducers, and a correlation exists between Cyclin K degradation and cellular sensitivity. dCeMM4 can be used in studies related to T-cell malignancies .
Cat. No.: HY-P1378A
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Cat. No.: HY-W008820R
CAS No.: 110-94-1
Cat. No.: HY-W099859
CAS No.: 939-27-5
2-Ethylnaphthalene is an alkyl-substituted polyaromatic. 2-Ethylnaphthalene has a negative correlation with Glomus relative abundance in arbuscular mycorrhizal fungi community .
Cat. No.: HY-16984
CAS No.: 1705602-02-3
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GNE-4997 is a potent and selective interleukin-2-inducible T-cell kinase (ITK) inhibitor with a Ki of 0.09 nM, and the correlation between the basicity of solubilizing elements in GNE-4997 and off-target antiproliferative effects reduces cytotoxicity .
Cat. No.: HY-P1378
CAS No.: 134500-80-4
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Cat. No.: HY-113085R
CAS No.: 1637-75-8
Category:
Natural Products Plants Other Families Extract Disease Research Fields Inflammation/Immunology
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Cat. No.: HY-N15784
CAS No.: 2707415-29-8
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Cat. No.: HY-D2757
CAS No.: 135926-06-6
Cat. No.: HY-147915
CAS No.: 2416220-53-4
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Benz-AP is a potent photosensitizer. Benz-AP produces singlet oxygen, with a negative correlation with hCES2 (Human carboxylesterase 2) activity. Benz-AP displays a higher photocytotoxicity potency in cancer cells under low hCES2 environments. Upon TPE (Two-photon excitation), Benz-AP produces ROS and kills cancer cells and tumor spheroids .
Cat. No.: HY-N1186
CAS No.: 109194-60-7
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Cat. No.: HY-116240
CAS No.: 108895-49-4
Synonyms: ddEtUrd
2′,3′-Dideoxy-5-ethyluridine (ddEtUrd) is an antiretroviral compound with weak anti-HIV activity. The 3'-substituted derivatives of 2′,3′-Dideoxy-5-ethyluridine did not show significant antiviral effects. 2′,3′-Dideoxy-5-ethyluridine was less potent in inhibiting HIV replication in human MT4 lymphocytes. Although phosphorylation induced by 2′,3′-Dideoxy-5-ethyluridine is essential for antiviral activity, there is no strong correlation between its affinity for human dThd kinase or dCyd kinase .
Cat. No.: HY-104080
CAS No.: 1125593-85-2
HG-5-88-01 is an EGFR inhibitor. HG-5-88-01 exhibits no significant correlation in its anti-cancer sensitivity with the expression level of EGFR .
Cat. No.: HY-N15768
CAS No.: 1917340-42-1
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Cat. No.: HY-D3349
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Fluorne rhodamine picolyl azide is a fluorescent dye used for optical microscopy and nanoscopy, which can be applied in fluorescence correlation spectroscopy (FCS), stimulated emission depletion (STED) nanoscopy, biomolecule labeling, and live-cell imaging .
Cat. No.: HY-N21954
CAS No.: 1148039-73-9
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
