Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
201 Results for "
defense
" in MedChemExpress (MCE) Product Catalog:
Products (201)
201 Results for "defense" in MCE Product Catalog:
46
Category:
Simaroubaceae Extract Terpenoids Diterpenoids Plants Disease Research Fields Cancer Brucea javanica (L.) Merr.
Target:
29
29 Cited Publications
Cat. No.: HY-W250119
CAS No.: 23411-34-9
Synonyms: EDTA disodium calcium salt hydrate; Ethylenediaminetetraacetic acid disodium calcium salt hydrate
13
Research Areas:
Cardiovascular Disease Neurological Disease Metabolic Disease
Enalapril (MK-421) is an orally active angiotensin-converting enzyme inhibitor. Enalapril blocks the conversion of angiotensin I to angiotensin II, regulates the renin-angiotensin system, reduces preload and afterload, and decreases plasma angiotensin II levels. Enalapril inhibits apoptosis, reduces nitric oxide metabolite levels, stabilizes endothelial cells, enhances endothelial antioxidant defense, scavenges reactive oxygen species (ROS), and alleviates neuronal damage. Enalapril attenuates glutathione depletion, protein/lipid oxidation, tissue damage, and type III collagen immunolabeling in organs of diabetic rats. Enalapril reduces systolic blood pressure and urinary albumin excretion, and delays the progression of diabetic cardiac/renal injury. Enalapril is used in research related to asymptomatic left ventricular dysfunction, congestive heart failure, Alzheimer's disease, diabetes mellitus, acute myocardial infarction, atrial fibrillation, hypertension, cerebral ischemia, chronic heart failure, and single-ventricle physiology .
13
Research Areas:
Cardiovascular Disease Neurological Disease Metabolic Disease
Enalapril maleate (MK-421 maleate) is an orally active angiotensin-converting enzyme inhibitor. Enalapril maleate blocks the conversion of angiotensin I to angiotensin II, regulates the renin-angiotensin system, reduces preload and afterload, and decreases plasma angiotensin II levels. Enalapril maleate inhibits apoptosis, reduces nitric oxide metabolite levels, stabilizes endothelial cells, enhances endothelial antioxidant defense, scavenges reactive oxygen species (ROS), and alleviates neuronal damage. Enalapril maleate attenuates glutathione depletion, protein/lipid oxidation, tissue damage, and type III collagen immunolabeling in organs of diabetic rats. Enalapril maleate reduces systolic blood pressure and urinary albumin excretion, and delays the progression of diabetic cardiac/renal injury. Enalapril maleate is used in research related to asymptomatic left ventricular dysfunction, congestive heart failure, Alzheimer's disease, diabetes mellitus, acute myocardial infarction, atrial fibrillation, hypertension, cerebral ischemia, chronic heart failure, and single-ventricle physiology .
10
10 Cited Publications
Cat. No.: HY-N1913
CAS No.: 76822-21-4
Synonyms: Dan shen suan A; Salvianic acid A
10
10 Cited Publications
Cat. No.: HY-N1913A
CAS No.: 81075-52-7
Synonyms: Dan shen suan A sodium; Salvianic acid A sodium
3
3 Cited Publications
Cat. No.: HY-B0842
CAS No.: 23564-05-8
Target:
Environmental Pollutants Fungal Apoptosis Bcl-2 Family Caspase TNF Receptor SOD Reactive Oxygen Species (ROS)
Research Areas:
Thiophanate-Methyl is a pesticide residue and fungicide. Thiophanate-Methyl induces hepatotoxicity via caspase-3-mediated apoptosis and oxidative stress, thereby causing metabolic imbalance in the liver of zebrafish. Thiophanate-Methyl impairs the rhizobacteria-mediated defense response of cucumber against fusarium wilt .
3
2
2 Cited Publications
Synonyms: Menadione sodium bisulfite; Vitamin K3 sodium bisulfite
Target:
Research Areas:
Menadione bisulfite (sodium) is used as an agent to induce acute oxidative stress, and to function as a plant-defense activator against several pathogens.
2
Category:
Kochia scoparia L. Schrad. Amino acids Chenopodiaceae Extract Plants Disease Research Fields Inflammation/Immunology
Target:
2
2 Cited Publications
Cat. No.: HY-P3021
CAS No.: 12671-19-1
Target:
Research Areas:
Human milk lysozyme is the lysozyme found in human milk. Human milk lysozyme is thought to be a key defense factor in protecting the gastrointestinal tract of newborns against bacterial infection .
2
2 Cited Publications
Cat. No.: HY-B1513
CAS No.: 10016-20-3
Category:
Zea mays L. Polysaccharides Other Diseases Plants Gramineae Extract Disease Research Fields Saccharides
Target:
2
Target:
Research Areas:
Et-29 (NRD167) is a selective SIRT5 inhibitor. Et-29 increases the levels of total protein succinylation and citrate synthase succinylation in cells. Et-29 reduces serum CTX-I levels and blocks Ferroptosis by downregulating the SIRT5/ACSL4/LPCAT3/ALOX15 axis and restoring antioxidant defense. Et-29 decreases bone resorption and improves trabecular bone mass and microarchitecture. Et-29 is applicable for research related to osteoporosis and hepatocellular carcinoma .
2
2 Cited Publications
Synonyms: L-Sulforaphane
1
Target:
1
1 Cited Publications
Target:
Research Areas:
1
Target:
Research Areas:
1
1 Cited Publications
Synonyms: Ubiquinone Q9; CoQ9; Ubiquinone 9
Category:
Cardiovascular Disease Quinones Microorganisms Benzene Quinones Endogenous metabolite Disease Research Fields
Target:
1
Category:
Lignans Phenols Polyphenols Phenylpropanoids Plants Other Families Extract Disease Research Fields Cancer
Target:
1
1 Cited Publications
Synonyms: Methyl caprooyl tyrosinate
Target:
Research Areas:
MHP (Methyl caprooyl tyrosinate) is an activator of sphingosine kinase (SPHK1), and significantly stimulates CAMP mRNA and protein production. MHP (Methyl caprooyl tyrosinate) enhances antimicrobial defense and innate immunity .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
