299 Results for "

flavonoid inhibitor

" in MedChemExpress (MCE) Product Catalog:
Products (299)

299 Results for "flavonoid inhibitor" in MCE Product Catalog:

230
Quercetin
Quercetin
0 Images
230 Publications Verification
Cat. No.: HY-18085
CAS No.: 117-39-5
Category:  

Flavonols Anti-aging Endocrine diseases Plants Endogenous metabolite Human Gut Microbiota Metabolites other families Flavonoids Microorganisms Immune System Disorder Leguminosae Sunscreen Disease markers Cosmetic Research Disease Research Fields Glycyrrhiza uralensis Fisch. Cancer

Target:  

Reactive Oxygen Species (ROS) PI3K Autophagy Mitophagy Apoptosis

Quercetin, a natural flavonoid, is a stimulator of recombinant SIRT1 and also a PI3K inhibitor with IC50 of 2.4 μM, 3.0 μM and 5.4 μM for PI3K γ, PI3K δ and PI3K β, respectively .
loading...
    loading...
View All Sizes
229
Quercetin hydrate
Quercetin hydrate
0 Images
229 Cited Publications
Cat. No.: HY-18085A
CAS No.: 849061-97-8
Target:  

PI3K Autophagy Mitophagy Apoptosis Reactive Oxygen Species (ROS)

Research Areas:  

Cancer

Quercetin hydrate, a natural flavonoid, is a stimulator of recombinant SIRT1 and also a PI3K inhibitor with IC50 of 2.4 μM, 3.0 μM and 5.4 μM for PI3K γ, PI3K δ and PI3K β, respectively .
loading...
    loading...
View All Sizes
224
Quercetin dihydrate
Quercetin dihydrate
0 Images
224 Cited Publications
Cat. No.: HY-N0146
CAS No.: 6151-25-3
Category:  

Flavonols other families Flavonoids Phenols Polyphenols Plants Disease Research Fields Cancer

Target:  

PI3K Apoptosis

Quercetin dihydrate, a natural flavonoid, is a stimulator of recombinant SIRT1 and a PI3K inhibitor with IC50s of 2.4 μM, 3.0 μM and 5.4 μM for PI3K γ, PI3K δ and PI3K β, respectively .
loading...
    loading...
View All Sizes
96
Luteolin monohydrate
Luteolin monohydrate
0 Images
96 Cited Publications
Cat. No.: HY-W303895
CAS No.: 6113-16-2
Target:  

Keap1-Nrf2 Apoptosis Autophagy Endogenous Metabolite

Research Areas:  

Others Cancer

Luteolin (monohydrate) is the monohydrate of Luteolin. Luteolin (Luteoline), a flavonoid, is also a potent Nrf2 inhibitor. Luteolin has anti-inflammatory and anticancer properties, induces apoptosis and cell cycle arrest in multiple human cancer cell lines, including non-small lung cancer cells, and inhibits cell metastasis and angiogenesis .
loading...
    loading...
View All Sizes
85
Kaempferol
Kaempferol
0 Images
85 Cited Publications
Cat. No.: HY-14590
CAS No.: 520-18-3
Purity:  99.92%
Synonyms: Kempferol; Robigenin
Category:  

Flavonols Anti-aging Plants Endogenous metabolite Human Gut Microbiota Metabolites other families Flavonoids Microorganisms Sunscreen Phenols Polyphenols Cosmetic Research Disease Research Fields Cancer

Target:  

Estrogen Receptor/ERR Autophagy Mitophagy Apoptosis HIV Parasite Endogenous Metabolite

Kaempferol (Kempferol), a flavonoid found in many edible plants, inhibits estrogen receptor α expression in breast cancer cells and induces apoptosis in glioblastoma cells and lung cancer cells by activation of MEK-MAPK. Kaempferol can be uesd for the research of breast cancer .
loading...
    loading...
View All Sizes
36
Isoliquiritigenin
Isoliquiritigenin
0 Images
36 Cited Publications
Cat. No.: HY-N0102
CAS No.: 961-29-5
Synonyms: GU17; ISL; Isoliquiritigen; SJ000286237
Category:  

Plants Infection Flavonoids Microorganisms Chalcones Leguminosae Phenols Polyphenols Disease Research Fields Glycyrrhiza uralensis Fisch. Inflammation/Immunology

Target:  

Aldose Reductase Influenza Virus Autophagy Apoptosis

Isoliquiritigenin is an anti-tumor flavonoid from the root of Glycyrrhiza uralensis Fisch., which inhibits aldose reductase with an IC50 of 320 nM. Isoliquiritigenin is a potent inhibitor of influenza virus replication with an EC50 of 24.7 μM.
loading...
    loading...
View All Sizes
35
Rutin
Rutin
0 Images
35 Cited Publications
Cat. No.: HY-N0148
CAS No.: 153-18-4
Synonyms: Rutoside; Quercetin 3-O-rutinoside
Category:  

Flavonols Plants other families Flavonoids Leguminosae Sunscreen Phenols Polyphenols Cosmetic Research Disease Research Fields Glycyrrhiza uralensis Fisch. Cancer

Target:  

Amyloid-β Autophagy Apoptosis Endogenous Metabolite

Rutin (Rutoside) is a flavonoid found in many plants and shows a wide range of biological activities including anti-inflammatory, antidiabetic, antioxidant, neuroprotective, nephroprotective, hepatoprotective and reducing Aβ oligomer activities. Rutin is also a CBR1 inhibitor, which can cross the blood brain barrier. Rutin attenuates vancomycin-induced renal tubular cell apoptosis via suppression of apoptosis, mitochondrial dysfunction, and oxidative stress .
loading...
    loading...
View All Sizes
29
Phloretin
Phloretin
0 Images
29 Cited Publications
Cat. No.: HY-N0142
CAS No.: 60-82-2
Synonyms: NSC 407292; RJC 02792
Category:  

Rosaceae Plants Dihydrochalcones Endogenous metabolite Human Gut Microbiota Metabolites Flavonoids Microorganisms Malus pumila Mill. Phenols Polyphenols Disease Research Fields Cancer

Target:  

SGLT Endogenous Metabolite GLUT

Phloretin (NSC 407292; RJC 02792) is a flavonoid extracted from Malus pumila Mill.，has anti-inflammatory activities. Phloridzin is a specific，competitive and orally active inhibitor of sodium/glucose cotransporters in the intestine (SGLT1) and kidney (SGLT2). Phloretin inhibits Yeast-made GLUT1 as well as Human erythrocyte GLUT1 with IC50values of 49 μM and 61 μM，respectively .Phloretin has the potential for the treatment of rheumatoid arthritis (RA) and allergic airway inflammation .
loading...
    loading...
View All Sizes
25
Wogonin
Wogonin
0 Images
25 Cited Publications
Cat. No.: HY-N0400
CAS No.: 632-85-9
Category:  

Flavonoids Flavones Labiatae Phenols Polyphenols Plants Disease Research Fields Medicago truncatula Gaertn. Inflammation/Immunology

Target:  

CDK Wnt Autophagy Apoptosis

Wogonin is a naturally occurring mono-flavonoid, can inhibit the activity of CDK8 and Wnt, and exhibits anti-inflammatory and anti-tumor effects.
loading...
    loading...
View All Sizes
21
Diosmetin
Diosmetin
0 Images
21 Cited Publications
Cat. No.: HY-N0125
CAS No.: 520-34-3
Category:  

Human Gut Microbiota Metabolites Flavonoids Flavones Citrus limon (L.) Burm. F. Rutaceae Plants Endogenous metabolite Disease Research Fields Cancer

Target:  

Cytochrome P450

Diosmetin is a natural flavonoid which inhibits human CYP1A enzyme activity with an IC50 of 40 μM in HepG2 cell.
loading...
    loading...
View All Sizes
20
Oroxylin A
Oroxylin A
0 Images
20 Cited Publications
Cat. No.: HY-N0560
CAS No.: 480-11-5
Synonyms: Baicalein 6-methyl ether; 6-Methoxybaicalein
Category:  

Flavonoids Flavones Phenols Polyphenols Plants Bignoniaceae Oroxylum indicum (Linn.) Bentham ex Kurz Disease Research Fields Cancer

Target:  

HIF/HIF Prolyl-Hydroxylase Autophagy Virus Protease

Oroxylin A is an active flavonoid compound with strong anti-cancer effects. Oroxylin A inhibits the IL-6/STAT3 pathway and NF-κB signaling, inhibits cell proliferation and induces apoptosis. Oroxylin A inhibits colitis-related carcinogenesis .
loading...
    loading...
View All Sizes
19
Astragalin
Astragalin
0 Images
19 Cited Publications
Cat. No.: HY-N0015
CAS No.: 480-10-4
Synonyms: Astragaline; 3-Glucosylkaempferol; Kaempferol 3-β-D-glucopyranoside
Category:  

Flavonols Plants Flavonoids Microorganisms Phenols Polyphenols Disease Research Fields Cancer Santalaceae Thesium chinense Turcz.

Target:  

Apoptosis NF-κB

Astragalin (Astragaline) a flavonoid with anti-inflammatory, antioxidant, anticancer, bacteriostatic activity. Astragalin inhibits cancer cells proliferation and migration, induces apoptosis. Astragalin is orally active and provides nerve and heart protection, and resistance against and osteoporosis .
loading...
    loading...
View All Sizes
18
Baohuoside I
Baohuoside I
0 Images
18 Cited Publications
Cat. No.: HY-N0011
CAS No.: 113558-15-9
Synonyms: Icariin-II; Icariside-II
Category:  

Flavonols Anti-aging Plants Endogenous metabolite Human Gut Microbiota Metabolites Flavonoids Epimedium koreanum Nakai Phenols Polyphenols Berberidaceae Disease Research Fields Inflammation/Immunology Endocrinology Cancer

Target:  

CXCR Apoptosis

Baohuoside I, a flavonoid isolated from Epimedium koreanum Nakai, acts as an inhibitor of CXCR4, downregulates CXCR4 expression, induces apoptosis and shows anti-tumor activity.
loading...
    loading...
View All Sizes
18
Liquiritin
Liquiritin
0 Images
18 Cited Publications
Cat. No.: HY-N0376
CAS No.: 551-15-5
Category:  

Neurological Disease Plants Flavonoids Monophenols Leguminosae Flavonones Phenols Disease Research Fields Glycyrrhiza uralensis Fisch. Inflammation/Immunology

Liquiritin, a flavonoid isolated from Glycyrrhiza uralensis, is a potent and competitive AKR1C1 inhibitor with IC50s of 0.62 μM, 0.61 μM, and 3.72μM for AKR1C1, AKR1C2 and AKR1C3, respectively. Liquiritin efficiently inhibits progesterone metabolism mediated by AKR1C1 in vivo . Liquiritin acts as an antioxidant and has neuroprotective, anti-cancer and anti-inflammatory activity .
loading...
    loading...
View All Sizes
16
Tangeretin
Tangeretin
0 Images
16 Cited Publications
Cat. No.: HY-N0133
CAS No.: 481-53-8
Synonyms: Tangeritin; NSC53909; NSC618905
Category:  

other families Flavonoids Flavones Plants Disease Research Fields Cancer

Target:  

Notch Apoptosis

Tangeretin (Tangeritin), a flavonoid from citrus fruit peels, has been proven to play an important role in anti-inflammatory responses and neuroprotective effects in several disease models, and is a Notch-1 inhibitor.
loading...
    loading...
View All Sizes
16
Xanthohumol
Xanthohumol
0 Images
16 Cited Publications
Cat. No.: HY-N1067
CAS No.: 6754-58-1
Category:  

Infection Flavonoids Chalcones Humulus lupulus L. Phenols Polyphenols Plants Moraceae Disease Research Fields

Target:  

COX Acyltransferase Apoptosis HSV CMV Influenza Virus

Xanthohumol is one of the principal flavonoids isolated from hops, the inhibitor of diacylglycerol acetyltransferase (DGAT), COX-1 and COX-2, and shows anti-cancer and anti-angiogenic activities. Xanthohumol also has antiviral activity against bovine viral diarrhea virus (BVDV), rhinovirus, HSV-1, HSV-2 and cytomegalovirus (CMV).
loading...
    loading...
View All Sizes
15
Pinocembrin
Pinocembrin
0 Images
15 Cited Publications
Cat. No.: HY-N0575
CAS No.: 480-39-7
Synonyms: (+)-Pinocoembrin; Dihydrochrysin; Galangin flavanone
Category:  

Alpinia katsumadai Hayata Plants other families Flavonoids Animals Leguminosae Flavonones Phenols Polyphenols Pteris vittata L. Disease Research Fields Glycyrrhiza uralensis Fisch. Inflammation/Immunology Cancer Zingiberaceae

Target:  

Bacterial Reactive Oxygen Species (ROS) Autophagy

Pinocembrin ((+)-Pinocoembrin) is a flavonoid found in propolis, acts as a competitive inhibitor of histidine decarboxylase, and is an effective anti-allergic agent, with antioxidant, antimicrobial and anti-inflammatory properties .
loading...
    loading...
View All Sizes
15
Neobavaisoflavone
Neobavaisoflavone
0 Images
15 Cited Publications
Cat. No.: HY-N0720
CAS No.: 41060-15-5
Category:  

Flavonoids Leguminosae Phenols Polyphenols Psoralea corylifolia L. Plants Disease Research Fields Cancer Isoflavones

Target:  

Apoptosis DNA/RNA Synthesis

Neobavaisoflavone, a flavonoid, is isolated from the seeds of Psoralea corylifolia. Neobavaisoflavone exhibits anti-inflammatory, anti-cancer and anti-oxidation activities. Neobavaisoflavone inhibits DNA polymerase at moderate to high concentrations. Neobavaisoflavone also inhibits platelet aggregation .
loading...
    loading...
View All Sizes
15
Hydroxysafflor yellow A
Hydroxysafflor yellow A
0 Images
15 Cited Publications
Cat. No.: HY-N0567
CAS No.: 78281-02-4
Synonyms: Safflomin A; HSYA
Category:  

Flavonoids Chalcones Monophenols Carthamus tinctorius L. Phenols Plants Compositae Disease Research Fields Cancer

Target:  

Apoptosis Autophagy

Hydroxysafflor yellow A (Safflomin A) is a natural product of flavonoids isolated from safflower. Hydroxysafflor yellow A can inhibit cell proliferation and promote apoptosis through the autophagy pathway. Hydroxysafflor yellow A has anti-inflammatory, antioxidant and antitumor effects. Hydroxysafflor yellow A can be used in the study of cardiovascular disease .
loading...
    loading...
View All Sizes
15
Cynaroside
Cynaroside
0 Images
15 Cited Publications
Cat. No.: HY-N0540
CAS No.: 5373-11-5
Synonyms: Luteolin 7-glucoside; Luteolin 7-O-β-D-glucoside
Category:  

Flavones Plants Compositae Infection Flavonoids Centaurea ornata Phenols Polyphenols Umbelliferae Disease Research Fields Cirsium vulgare(Savi) Ten.

Target:  

Influenza Virus DNA/RNA Synthesis Apoptosis Parasite Bacterial Fungal

Cynaroside (Luteolin 7-glucoside) is a flavonoid compound that exhibits anti-oxidative capabilities. Cynaroside is also a potent influenza RNA-dependent RNA polymerase inhibitor with an IC50 of 32 nM. Cynaroside also is a promising inhibitor for H2O2-induced apoptosis, has cytoprotection against oxidative stress-induced cardiovascular diseases. Cynaroside also has antibacterial, antifungal and anticancer activities, antioxidant and anti-inflammatory activities .
loading...
    loading...
View All Sizes
Assay Types