44 Results for "

ginger

" in MedChemExpress (MCE) Product Catalog:
Products (44)

44 Results for "ginger" in MCE Product Catalog:

14
14 Publications Verification
Cat. No.: HY-14615
CAS No.: 23513-14-6
Purity:  99.68%
Synonyms: (S)-(+)-[6]gingerol
[6]-Gingerol is an active compound isolated from Ginger (Zingiber officinale), exhibits a variety of biological activities including anticancer, anti-inflammation, and anti-oxidation.
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13
13 Cited Publications
Cat. No.: HY-14616
CAS No.: 555-66-8
Purity:  99.63%
Synonyms: [6]-Shogaol; 6-Shogaol
Shogaol ([6]-Shogaol), an active compound isolated from Ginger (Zingiber officinale Rosc), exhibits a variety of biological activities including anticancer, anti-inflammation, and anti-oxidation.
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5
5 Cited Publications
Cat. No.: HY-N0447
CAS No.: 23513-08-8
8-Gingerol can be found in the rhizome of ginger (Z. officinale) and has oral bioactivity. It activates TRPV1, with an EC50 value of 5.0 µM. 8-Gingerol inhibits COX-2 and also suppresses the growth of H. pylori in vitro. Additionally, 8-Gingerol exhibits anticancer, antioxidant, and anti-inflammatory properties by inhibiting the epidermal growth factor receptor (EGFR) and modulating its downstream STAT3/ERK pathway to suppress the proliferation, migration, and invasion of colorectal cancer cells. 8-Gingerol also exerts immunosuppressive effects by inhibiting oxidative stress, inducing cell cycle arrest, promoting apoptosis, and regulating autophagy. Furthermore, 8-Gingerol has cardioprotective effects. 8-Gingerol is promising for research in the fields of cancer, infection, immunosuppression, and cardiovascular diseases.
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5
5 Cited Publications
Cat. No.: HY-N2434
CAS No.: 36752-54-2
[10]-Shogaol is an orally active antioxidant. [10]-Shogaol can be extracted from ginger (Zingiber officinale). [10]-Shogaol1 inhibits COX-2 with an IC50 value of 7.5 μM. [10]-Shogaol inhibits the production of proinflammatory cytokines (IL-1β, IL-6). [10]-Shogaol inhibits NF-κB phosphorylation. [10]-Shogaol has anti-inflammatory effects. [10]-Shogaol has anticancer effects against Docetaxel (HY-B0011)-resistant prostate cancer. [10]-Shogaol exhibits larvicidal activity against L5 larvae of Angiostrongylus cantonensis .
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4
4 Cited Publications
Cat. No.: HY-N0448
CAS No.: 23513-15-7
10-Gingerol is an AMPK agonist, which is found in the ginger oleoresin from fresh rhizome with anti-inflammatory, antioxidant and anti-proliferative activities. 10-Gingerol suppresses neointimal hyperplasia and inhibits vascular smooth muscle cell proliferation. 10-Gingerol exhibits substantial scavenging activities with an IC50 value of 10.47 μM against DPPH radical, an IC50 value of 1.68 μM against superoxide radical and an IC50 value of 1.35 μM against hydroxyl radical. 10-Gingerol inhibits the proliferation of MDA-MB-231 tumor cell line with an IC50 of 12.1 μM. 10-Gingerol suppresses the proliferation, migration, invasion, and induced apoptosis through targeting the PI3K/Akt signaling pathway in MDA-MB-231/IR cells. 10-Gingerol can be used in research on various common cancers such as ovarian cancer and colon cancer, as well as colitis and neurodegenerative diseases .
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4
4 Cited Publications
Cat. No.: HY-14617
CAS No.: 27113-22-0
Purity:  99.87%
Synonyms: [6]-gingerone; [6]-Paradol
Paradol is a pungent phenolic substance found in ginger and other Zingiberaceae plants. Paradol is an effective inhibitor of tumor promotion in mouse skin carcinogenesis, binds to cyclooxygenase (COX)-2 active site.
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4
4 Cited Publications
Cat. No.: HY-N2435
CAS No.: 36700-45-5
[8]-Shogaol, a kind of stimulating compound in ginger, has antiplatelet (IC50=5 μM), anti-cancer and anti-inflammatory activity. [8]-Shogaol inhibited COX-2 (IC50=17.5 μM), which led to the decline of human leukemia cells. 8-Shogaol Selective direction TAK1 sum TAK1-TAB1 (IC50=5 μM), suppress IKK, Akt sum MAPK signal pathway, and reverse synovitis synovial sum Air dampness (RA).
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1
1 Cited Publications
Cat. No.: HY-14615R
CAS No.: 23513-14-6
Synonyms: (S)-(+)-[6]gingerol (Standard)
-Gingerol (Standard) is the analytical standard of -Gingerol. This product is intended for research and analytical applications. -Gingerol is an active compound isolated from Ginger (Zingiber officinale), exhibits a variety of biological activities including anticancer, anti-inflammation, and anti-oxidation.
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1
1 Cited Publications
Cat. No.: HY-133865
CAS No.: 143615-75-2
Purity:  98.01%
Diacetoxy-6-gingerdiol is a gingerol isolated with anti-inflammatory and antioxidant effects, which is found in the dichloromethane extract of rhizomes of ginger (Zingiber officinale Roscoe). Diacetoxy-6-gingerdiol protects the extracellular matrix of nucleus pulposus cells and ameliorates intervertebral disc degeneration by inhibiting the IL-1β-mediated NLRP3 pathway .
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1
1 Cited Publications
Cat. No.: HY-14616R
CAS No.: 555-66-8
Synonyms: [6]-Shogaol (Standard); 6-Shogaol (Standard)
Shogaol (Standard) is the analytical standard of Shogaol. This product is intended for research and analytical applications. Shogaol ( -Shogaol), an active compound isolated from Ginger (Zingiber officinale Rosc), exhibits a variety of biological activities including anticancer, anti-inflammation, and anti-oxidation.
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1
1 Cited Publications
Cat. No.: HY-14617R
CAS No.: 27113-22-0
Synonyms: [6]-gingerone (Standard); [6]-Paradol (Standard)
Paradol (Standard) is the analytical standard of Paradol. This product is intended for research and analytical applications. Paradol is a pungent phenolic substance found in ginger and other Zingiberaceae plants. Paradol is an effective inhibitor of tumor promotion in mouse skin carcinogenesis, binds to cyclooxygenase (COX)-2 active site.
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Cat. No.: HY-N1096
CAS No.: 120-14-9
Veratraldehyde is an orally active aromatic compound and antibacterial agent. Veratraldehyde can be isolated from essential oils of plants such as peppermint and ginger. Veratraldehyde targets the PilY1 protein. Veratraldehyde has antibacterial activity against Pseudomonas aeruginosa. Veratraldehyde has a repellent effect against mosquitoes and ticks. Veratraldehyde can be used as a flavoring agent .
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Cat. No.: HY-134635
CAS No.: 1080-12-2
Purity:  99.98%
Target:  

Bacterial Fungal HIV CDK

Research Areas:  

Infection Cancer

Dehydrozingerone is a ginger-derived component and cyclin D1 inhibitor that downregulates cyclin D1 expression and induces cell cycle G1 phase arrest. Dehydrozingerone reduces the proliferative capacity of castration-resistant prostate cancer cells under in vitro conditions. Dehydrozingerone reduces subcutaneous tumor growth by inhibiting cell proliferation and angiogenesis. Dehydrozingerone exerts antibacterial and antifungal activities via its α,β-unsaturated carbonyl conjugated system. Dehydrozingerone can be used in studies related to castration-resistant prostate cancer, bacterial infections, and food spoilage fungal infections .
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Cat. No.: HY-W1000105
CAS No.: 141-27-5
Synonyms: (E)-3,7-Dimethylocta-2,6-dienal
Geranial is an aromatic compound. It can be isolated from the fruits of Litsea cubeba Lour and the rhizomes of ginger (Zingiber officinale). Geranial inhibits LPS-induced phosphorylation of ERK1/2, JNK1/3 and IκB in macrophages. It suppresses the secretion of IL-1β, TNF-α and IL-6, as well as the expression of pro-IL-1β, iNOS and COX-2. Geranial increases ROS. It can be used in the research of inflammatory diseases .
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Cat. No.: HY-N9451
CAS No.: 84696-15-1
Ginger extract exhibits anti-cancer, anti-inflammatory and chemotherapeutic effects in vivo .
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Cat. No.: HY-115507
CAS No.: 1332290-68-2
NMac1 is an orally active Nm23/NDPK activator. NMac1 directly binds to Nm23-H1 and activates the NDPK activity of recombinant Nm23-H1 with an EC50 of 10.7 uM. NMac1 induces AMPK activation and inhibits mTOR and ERK, leading to mitochondrial OXPHOS dysregulation and suppressing mitochondrial ROS production, which in turn induces mitochondrial dysfunction in MDA-MB-231 cells. NMac1 inhibits Complex I activity and suppresses changes in morphology and actin cytoskeleton organization following Rac1 activation in MDA-MB-231 cells. NMac1 inhibits tumor invasion, migration and metastasis. NMac1 is useful for studying metastatic tumors, such as breast cancer. NMac1 can be isolated from the ginger cassumunar Roxb .
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Cat. No.: HY-N12643
CAS No.: 61871-71-4
Synonyms: [6]-gingerdione
[6]-Gingerdione is a prostaglandin synthesis inhibitor that can be isolated from ginger rhizomes.
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Cat. No.: HY-N16612
CAS No.: 143615-76-3
(3S,5S)-[6]-Gingerdiol is a cestocidal agent. (3S,5S)-[6]-Gingerdiol can be isolate from the roots of ginger. (3S,5S)-[6]-Gingerdiol shows cestocidal activity against H. nana .
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Cat. No.: HY-N1096S1
CAS No.: 143318-06-3
Veratraldehyde-d3 is the deuterium labeled Veratraldehyde (HY-N1096). Veratraldehyde is an orally active aromatic compound and antibacterial agent. Veratraldehyde can be isolated from essential oils of plants such as peppermint and ginger. Veratraldehyde targets the PilY1 protein. Veratraldehyde has antibacterial activity against Pseudomonas aeruginosa. Veratraldehyde has a repellent effect against mosquitoes and ticks. Veratraldehyde can be used as a flavoring agent .
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Cat. No.: HY-N15732
CAS No.: 503843-60-5
Methyl-8-gingerol is a compound that can be isolated from ginger .
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