3 Results for "

hTERT-RPE1

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "hTERT-RPE1" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-18399
CAS No.: 409086-68-6
Target:  

HSP NO Synthase

Research Areas:  

Cancer

YM-1 is a stable MKT-077 (HY-15096) analog and an orally active Hsp70 inhibitor. YM-1 induces cell death of HeLa cells and up-regulates the level of p53 and p21 proteins [1] .
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Cat. No.: HY-145337
Purity:  99.93%
Synonyms: FT385
Research Areas:  

Neurological Disease Cancer

FT3967385 (FT385) is a selective covalent inhibitor that targets the outer mitochondrial membrane deubiquitinase (Deubiquitinase) USP30 (IC50 = 1.5 nM, Ki = 0.014 μM). By inhibiting the enzymatic activity of USP30, FT3967385 relieves its negative regulation of the PINK1-Parkin mediated mitochondrial ubiquitination cascade, thereby enhancing mitophagy. FT3967385 can be used for mechanistic studies of neurodegenerative diseases associated with mitochondrial dysfunction, such as Parkinson's disease [1] .
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Cat. No.: HY-100832A
CAS No.: 1872382-48-3
Research Areas:  

Cancer

UNC3866 TFA is a potent antagonist of the CBX7-H3 interaction as determined by AlphaScreen (IC50=66±1.2 nM) and is more than 100-fold selective for CBX7 over the other nine members of this methyl-lysine (Kme) reader panel.
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