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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
26 Results for "
human hepatocellular liver carcinoma
" in MedChemExpress (MCE) Product Catalog:
Products (26)
26 Results for "human hepatocellular liver carcinoma" in MCE Product Catalog:
9
9
9 Cited Publications
Cat. No.: HY-N2334A
CAS No.: 16564-43-5
Synonyms: Chenodeoxycholylglycine sodium salt; Sodium glycochenodeoxycholate
Cat. No.: HY-B0766
CAS No.: 118159-48-1
Synonyms: SY801
Target:
Autophagy Apoptosis HBV HCV HSP Reactive Oxygen Species (ROS) Bcl-2 Family Glutathione S-transferase p38 MAPK NF-κB Microtubule/Tubulin ERK JNK TNF Receptor Interleukin Related CDK Cyclin G-associated Kinase (GAK) mTOR P-glycoprotein Ferroptosis
Research Areas:
Bicyclol (SY801) is an orally active derivative of the traditional Chinese medicine Schisandra chinensis, which has antiviral, anti-inflammatory, immunomodulatory, antioxidant, anti-steatosis, anti-fibrotic and anti-tumor activities. Bicyclol regulates the expression of heat shock proteins and plays an anti-apoptosis role in hepatocytes. Bicyclol reduces the activation of NF-κB and the levels of inflammatory factors in hepatocytes infected with hepatitis C virus (HCV) by inhibiting the activation of the ROS-MAPK-NF-κB pathway, and prevents ferroptosis in acute liver injury. Bicyclol can change the expression of Mdr-1, GSH/GST and Bcl-2, increase the intracellular concentration of anticancer drugs, and sensitize drug-resistant cells to anticancer drugs. Bicyclol inhibits the proliferation of human malignant hepatoma cells by regulating the PI3K/AKT pathway and the Ras/Raf/MEK/ERK pathway. Bicyclol can be used in the study of chronic hepatitis, acute liver injury, nonalcoholic fatty liver disease, liver fibrosis and hepatocellular carcinoma .
Cat. No.: HY-163959
CAS No.: 3036158-98-9
Target:
Research Areas:
PF-07853578 is an orally active PNPLA3 modulator. PF-07853578 significantly reduces human PNPLA3-I148M protein levels and effectively decreases hepatic triglyceride content by reducing this mutant protein. PNPLA3 degrader-1 can be used in the research of liver cirrhosis and hepatocellular carcinoma .
Cat. No.: HY-N2334AR
CAS No.: 16564-43-5
Synonyms: Chenodeoxycholylglycine sodium salt (Standard); Sodium glycochenodeoxycholate (Standard)
Category:
Category:
Cat. No.: HY-N15577
CAS No.: 1859979-00-2
Target:
Cat. No.: HY-P991566
CAS No.: 2983061-18-1
Cat. No.: HY-N10207
CAS No.: 1338332-27-6
Category:
Infection Natural Products Microorganisms Marine natural products Disease Research Fields Marine microorganism
Target:
Cat. No.: HY-138813R
Synonyms: SU-12662 hydrochloride (Standard)
Target:
Research Areas:
Glycochenodeoxycholic acid sodium salt (Standard) is the analytical standard of Glycochenodeoxycholic acid sodium salt. This product is intended for research and analytical applications. Glycochenodeoxycholic acid sodium salt (Sodium glycochenodeoxycholate) is a relatively toxic bile salt generated in the liver from chenodeoxycholic acid and glycine. Glycochenodeoxycholic acid sodium salt inhibits Autophagosome formation and impairs lysosomal function by inhibiting lysosomal proteolysis and increasing lysosomal pH in human normal liver cells, leading to the Apoptosis of human hepatocyte cells. Glycochenodeoxycholic acid sodium salt induces stemness and chemoresistance via activating STAT3 signaling pathway in hepatocellular carcinoma cells (HCC). Glycochenodeoxycholic acid sodium salt is promising for research in the field of cholestasis desease, hepatocellular carcinoma and primary sclerosing cholangitis (PSC) .
Cat. No.: HY-N15535
CAS No.: 871720-22-8
Target:
Cat. No.: HY-153547
CAS No.: 2521791-38-6
Target:
Research Areas:
HSP90-IN-21 (5e) is an antiplasmodial agent, with IC50 values of 0.04, 0.17 and 2.91 μM against erythrocytic stage of P. falciparum (Pf3D7 and PfDd2 strains), cytotoxicity of human liver hepatocellular carcinoma cell line (HepG2), respectively .
Cat. No.: HY-P705940
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ANGPTL8; hepatocellular carcinoma-Associated Gene TD26, Isoform CRA_a; Prev. C19orf80; hepatocellular carcinoma-Associated Gene TD26; RIFL; Chromosome 19 Open Reading Frame 80; Lipasin; Angiopoietin-Like 8; TD26; LOC55908; Refeeding-Induced Fat And liver
Species:
Human
Source:
E. coli
Cat. No.: HY-P7506
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ANGPTL8; hepatocellular carcinoma-Associated Gene TD26, Isoform CRA_a; Prev. C19orf80; hepatocellular carcinoma-Associated Gene TD26; RIFL; Chromosome 19 Open Reading Frame 80; Lipasin; Angiopoietin-Like 8; TD26; LOC55908; Refeeding-Induced Fat And liver
Species:
Human
Source:
HEK293
Cat. No.: HY-P70740
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGL1; Fibrinogen-Like Protein 1; Fibrinogen Like 1; LFIRE-1; HPS; HFREP1; Hepassocin; HP-041; HFREP-1; hepatocellular carcinoma-Related Sequence; Hepatocyte-Derived Fibrinogen-Related Protein 1; LFIRE1; liver Fibrinogen-Related Protein 1
Species:
Human
Source:
HEK293
Cat. No.: HY-P70737A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGL1; Fibrinogen-Like Protein 1; Fibrinogen Like 1; LFIRE-1; HPS; HFREP1; Hepassocin; HP-041; HFREP-1; hepatocellular carcinoma-Related Sequence; Hepatocyte-Derived Fibrinogen-Related Protein 1; LFIRE1; liver Fibrinogen-Related Protein 1
Species:
Human
Source:
HEK293
Cat. No.: HY-P704612
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGL1; Fibrinogen-Like Protein 1; Fibrinogen Like 1; LFIRE-1; HPS; HFREP1; Hepassocin; HP-041; HFREP-1; hepatocellular carcinoma-Related Sequence; Hepatocyte-Derived Fibrinogen-Related Protein 1; LFIRE1; liver Fibrinogen-Related Protein 1
Species:
Human
Source:
HEK293
Cat. No.: HY-P70737
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGL1; Fibrinogen-Like Protein 1; Fibrinogen Like 1; LFIRE-1; HPS; HFREP1; Hepassocin; HP-041; HFREP-1; hepatocellular carcinoma-Related Sequence; Hepatocyte-Derived Fibrinogen-Related Protein 1; LFIRE1; liver Fibrinogen-Related Protein 1
Species:
Human
Source:
HEK293
Cat. No.: HY-P72369
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGL1; Fibrinogen-Like Protein 1; Fibrinogen Like 1; LFIRE-1; HPS; HFREP1; Hepassocin; HP-041; HFREP-1; hepatocellular carcinoma-Related Sequence; Hepatocyte-Derived Fibrinogen-Related Protein 1; LFIRE1; liver Fibrinogen-Related Protein 1
Species:
Human
Source:
HEK293
Cat. No.: HY-P78875
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGL1; Fibrinogen-Like Protein 1; Fibrinogen Like 1; LFIRE-1; HPS; HFREP1; Hepassocin; HP-041; HFREP-1; hepatocellular carcinoma-Related Sequence; Hepatocyte-Derived Fibrinogen-Related Protein 1; LFIRE1; liver Fibrinogen-Related Protein 1
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
