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Results for "

hydroxyl

" in MedChemExpress (MCE) Product Catalog:

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B2196

Gastric mucin 3 Publications Verification	Antibiotic Bacterial	Infection Metabolic Disease
Gastric mucin is a glycoprotein with natural antibiotic function. Gastric mucin against Helicobacter pylori infection. Gastric mucin effectively scavenges hydroxyl radical. Gastric mucin play a major role in the protection of the gastrointestinal tract from acid, proteases, pathogenic microorganisms, and mechanical trauma .

HY-B2106

*Polidocanol,Hydroxyl* Value 40-60 mgKOH/g** Polyoxyethylene lauryl ether; Polyoxyethyleneglycol Dodecyl Ether	Environmental Pollutants Biochemical Assay Reagents	Cardiovascular Disease Cancer
Polidocanol is a sclerosing agent used successfully to treat extremity and esophageal varices and telangiectasias.

HY-121137

BMPO 1 Publications Verification BocMPO	Reactive Oxygen Species (ROS)	Others
BMPO (BocMPO) is a cell-permeable superior spin trap with favorable chemical and spectroscopic features. BMPO (BocMPO) can be used for detecting thiyl radicals, hydroxyl radicals, superoxide anions and glutathiyl radicals .

HY-Y0958

Methoxyamine hydrochloride 1 Publications Verification O-Methylhydroxylamine hydrochloride	DNA/RNA Synthesis Apoptosis	Cancer
Methoxyamine (O-Methylhydroxylamine) hydrochloride is an orally active and potent base excision repair (BER) inhibitor. Methoxyamine hydrochloride binds to 3’ hydroxyl groups that are left behind by 3-methylpurine-DNA glycosylase (MPG) following excision of the damaged base and thus inhibits BER activity. Methoxyamine hydrochloride binds directly to the apyrimidinic (AP) sites. Methoxyamine hydrochloride synergistically enhances the therapeutic efficacy of DNA-damaging agents .

HY-P2863

Deoxyribonuclease II 2 Publications Verification DNase II	Endonuclease	Others
Deoxyribonuclease II (DNase II) is an endonuclease that hydrolyzes the phosphodiester bonds of deoxyribonucleotides in native and denatured DNA, producing 3' phosphate and 5'-hydroxyl termini. Deoxyribonuclease II works best at acidic pH and is commonly used in biochemical research .

HY-126994

6′-Amino-D-luciferin	Fluorescent Dye	Others
6’-Amino-D-luciferin is a derivative of D-luciferin (HY-12591A) with an amino group replacing the 6-hydroxyl group. 6’-Amino-D-luciferin is a natural substrate of luciferase (Luc) and can be used for IVIS imaging in cell/animal experiments[1][2][3].

HY-135152

CYPMPO	Reactive Oxygen Species (ROS)	Cancer
CYPMPO is a spin-trapping reagent. CYPMPO, a cyclic DEPMPO-type nitrone, is evaluated for spin-trapping capabilities toward hydroxyl and superoxide radicals. anti-oxidant and anti-tumor?activity .

HY-D0913

1-Methyl-7-nitroisatoic anhydride 3 Publications Verification 1M7	Fluorescent Dye	Others
1-Methyl-7-nitroisatoic anhydride (1M7) is a reagent that detects local nucleotide flexibility, for probing 2'-hydroxyl reactivity, can be used for RNA structure analysis .

HY-134222A

N-Acetylserine N-Acetyl-L-serine	Endogenous Metabolite Complement System	Others
N-Acetylserine (N-Acetyl-L-serine) is a complement pathway modulator targeting activated third complement protein (C3b) and an amino-terminal residue (an N-terminal acetylation modification group). N-Acetylserine reacts with the exposed thioester group of C3b via its hydroxyl group, thereby blocking the covalent binding of glycerol to this thioester group. N-Acetylserine widely exists in soluble proteins of mammalian cells (accounting for approximately 80% of such proteins). N-Acetylserine has a blocking property that prevents direct Edman sequencing of proteins; deblocking is achievable through trifluoroacetic acid-catalyzed N→O acetyl migration followed by β-elimination. N-Acetylserine is suitable for sequencing of proteins with N-terminal acetylserine modification .

HY-W034344

Sodium methanesulfonate	Biochemical Assay Reagents	Others
Sodium methanesulfonate is a hygroscopic atmospheric aerosol, which typically forms from the reaction of methanesulfonic acid with sodium chloride or sea salt particles. Sodium methanesulfonate can serve as a substrate for oxidation reactions, undergoing heterogeneous oxidation by hydroxyl radicals at the air-aerosol interface, thereby initiating subsequent aerosol-phase chain reactions. Sodium methanesulfonate exhibits significant temperature-dependent deliquescence and efflorescence properties; particularly at lower temperatures relevant to the troposphere, its deliquescence and efflorescence relative humidity increase accordingly .

HY-100592

Nicaraven 2 Publications Verification	Reactive Oxygen Species (ROS)	Cancer
Nicaraven is a novel chemically synthesized hydroxyl radical-specific scavenger.

HY-W115721

Rhodizonic acid disodium Sodium rhodizonate dibasic	Reactive Oxygen Species (ROS) DNA/RNA Synthesis	Others
Rhodizonic acid disodium (Sodium rhodizonate dibasic) is a transition metal-dependent pro-oxidant and lead detection agent that induces reactive oxygen species generation, DNA damage, and inhibits Aconitase activity. Rhodizonic acid disodium generates superoxide anion radicals in an iron (II)-dependent manner, leading to aconitase inactivation. Rhodizonic acid disodium also triggers hydroxyl radical-mediated DNA strand breaks and 8-OHdG formation via copper ion reduction. Rhodizonic acid disodium reacts with lead to form a scarlet precipitate, with the color intensity proportional to lead content, enabling qualitative or quantitative analysis of lead. Rhodizonic acid disodium can also be used for real-time visualization of the dynamic process of lead sequestration in the plant rhizosphere and evaluation of the effects of environmental factors such as soil type on the stability of lead-sequestering structures .

HY-76222

Isatoic anhydride	Drug Intermediate	Others
Isatoic anhydride is a single-adduct forming reagent and a monofunctional SHAPE reagent. Isatoic anhydride reacts with the 2'-hydroxyl group of RNA nucleotides via a single reactive group to form a single adduct, without forming cross-links between nucleotides. In SHAPE-JuMP experiments, Isatoic anhydride serves as a control reagent for single-adduct formation, which is used to distinguish true cross-links from single-adduct formation .

HY-132180A

Seco-DUBA	ADC Payload DNA/RNA Synthesis	Inflammation/Immunology Cancer
Seco-DUBA hydrochloride is a DNA-targeting cytotoxic agent. Seco-DUBA hydrochloride binds to the minor groove of A-T-rich DNA regions, alkylates the adenine N3 residue, and undergoes spontaneous spirocyclization to generate active DUBA (HY-160969). Seco-DUBA hydrochloride exerts cytotoxic activity against human cancer cells. The reduced hydrophobicity of Seco-DUBA hydrochloride supports the development of antibody-drug conjugates .

HY-N6964

Quercetin 3-O-β-D-(6''-p-coumaroyl)glucopyranosyl(1→2)-α-L-rhamnopyranoside Quercetin-3-O-[2-O-(6-O-p-hydroxyl-E-coumaroyl)-D-glucosyl]-(1→2)-L-rhamnoside	Others	Metabolic Disease
Quercetin 3-O-β-D-(6''-p-coumaroyl)glucopyranosyl(1→2)-α-L-rhamnopyranoside (Quercetin-3-O-[2-O-(6-O-p-hydroxyl-E-coumaroyl)-D-glucosyl]-(1→2)-L-rhamnoside) is one of the major antioxidants of Ginkgo biloba leaves .

HY-130025

HKOCl-3 2 Publications Verification	Fluorescent Dye	Others
HKOCl-3 is a highly sensitive and selective fluorescent probe for detecting hypochlorous acid.E_x: 490 nm; E_m 527 nm .

HY-W004289

Methyl pentadecanoate	Drug Derivative	Others
Methyl pentadecanoate is a fatty acid ester that can be isolated from extracts of L. wallichi. Methyl pentadecanoate is formed by the condensation of the carboxyl group of pentadecanoic acid with the hydroxyl group of methanol .

HY-15157

Calcitetrol 1α, 24, 25-Trihydroxy VD3	VD/VDR	Metabolic Disease
Calcitetrol(1α, 24, 25-Trihydroxy VD3) is the hormonally active form of vitamin D with three hydroxyl groups.

HY-W012971

5-Amino-1-pentanol	Biochemical Assay Reagents	Others
5-Amino-1-pentanol is a linker containing a hydroxyl group and amine group. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.

HY-P4280

Arg-Tyr H-Arg-Tyr-OH	Reactive Oxygen Species (ROS)	Others
Arg-Tyr is a dipeptide which has strong hydroxyl-radical and hydrogen-peroxide scavenging activity .

HY-W099630

Heptadecan-9-ol 9-Heptadecanol	Biochemical Assay Reagents	Others
Heptadecan-9-ol (9-Heptadecanol) is a lipid with a secondary hydroxyl group and two non-polar tails.

HY-N0674B

*Dehydrocorydaline (hydroxyl)* Maximum Cited Publications 43 Publications Verification 13-Methylpalmatine (hydroxyl)	Bcl-2 Family Caspase PARP p38 MAPK Parasite Autophagy	Infection Inflammation/Immunology Cancer
Dehydrocorydaline (13-Methylpalmatine) hydroxyl is an alkaloid that regulates protein expression of Bax, Bcl-2; activates caspase-7, caspase-8, and inactivates PARP. Dehydrocorydaline hydroxyl elevates p38 MAPK activation. Anti-inflammatory and anti-cancer activities. Dehydrocorydaline hydroxyl shows strong anti-malarial effects (IC50=38 nM), and low cytotoxicity (cell viability > 90%) using P. falciparum 3D7 strain.

HY-D1159

HKOH-1r 5+ Cited Publications	Reactive Oxygen Species (ROS) Fluorescent Dye	Others
HKOH-1r is a highly sensitive green fluorescent probe for the specific detection of ·OH in living cells with a maximum excitation wavelength and emission wavelength of 500 nm and 520 nm, respectively .

HY-132280

Tirilazad U 74006F free base	Reactive Oxygen Species (ROS) SARS-CoV Virus Protease	Neurological Disease Inflammation/Immunology
Tirilazad (U 74006F free base) is a neuroprotective agent. Tirilazad can also bind tightly to the main protease of the COVID-19 virus and exert anti-SARS-CoV-2 activity. Tirilazad scavenges hydroxyl and lipid peroxyl free radicals and maintains the levels of endogenous antioxidants. Tirilazad reduces cerebral infarct volume and improves neurobehavioral scores in animal models of focal ischemia. Tirilazad can be used in research related to ischemic stroke and subarachnoid hemorrhage .

HY-W460072

tert-Butyl 7-hydroxyheptanoate	Biochemical Assay Reagents	Others
tert-Butyl 7-hydroxyheptanoate is a linker with a hydroxyl group and a t-butyl ester. The hydroxyl group allows for further derivatization or replacement with many other reactive functional groups. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

HY-P2844

Polynucleotide kinase	DNA/RNA Synthesis	Metabolic Disease
Polynucleotide Kinase is a DNA repair enzyme. Polynucleotide Kinase possesses both a 5’-kinase activity that catalyzes the transfer of phosphate from ATP to a 5’-hydroxyl (OH) terminus and also a 3’-phosphatase activity that converts 3’-phosphate termini to 3’-OH termini .

HY-D1151

HKOH-1 3 Publications Verification	Reactive Oxygen Species (ROS) Fluorescent Dye	Others
HKOH-1 is a highly sensitive green fluorescent probe for the specific detection of ·OH in living cells with a maximum excitation wavelength and emission wavelength of 500 nm and 520 nm, respectively .

HY-161973

Hydroxyl-ML-210	Ligands for Target Protein for PROTAC	Cancer
Hydroxyl-ML-210 is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs). Hydroxyl-ML-210 can be used for synthesis ZX782 (HY-161972) .

HY-113490

15-KETE	Drug Derivative	Metabolic Disease
15-KETE (15-KETE) is produced by oxidation of the 15-hydroxyl of 15-HETE.

HY-176513

Cy-OH-LP	Fluorescent Dye	Others
Cy-OH-LP is a turn-on fluorescent and photoacoustic probe that can detect lipid-associated hydroxyl radicals. Cy-OH-LP can be oxidized to Cy7 in the presence of hydroxyl radicals, which displays weak fluorescent and photoacoustic signals in water-soluble environments and strong fluorescent and photoacoustic signals in lipid-rich environments due to its lipid solubility. Cy-OH-LP can be used for in vivo photoacoustic imaging of hydroxyl radicals .

HY-W039729

5-(Boc-amino)-1-pentanol	Biochemical Assay Reagents	Others
5-(Boc-amino)-1-pentanol is a linker containing a hydroxyl group and Boc-protected amino group. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The Boc group can be deprotected under mild acidic conditions to form the free amine.

HY-174967C

4-Arm-PEG20000-OH	Biochemical Assay Reagents	Others
4-Arm-PEG20000-OH is a PEG derivative with a four-arm structure and a hydroxyl (OH) functional group. 4-Arm-PEG20000-OH reacts with functional groups on biomolecules (such as proteins, peptides, antibodies, etc.) through hydroxyl groups and can be used for drug delivery .

HY-W683499

Lauryl hydroxysultaine LHSB	Biochemical Assay Reagents	Others
Lauryl hydroxysultaine (LHSB), a surfactant, is comprised of a core Sultaine structure with a sulphopropyl quaternary ammonium salt, an alkyl group and a hydroxyl group .

HY-N16658

Asperilin NSC 85238	Glutathione Peroxidase	Inflammation/Immunology
Asperilin (NSC 85238) is an orally active sesquiterpene lactone. Asperilin is an effective hydroxyl radical scavenger. Asperilin significantly enhance the lipid peroxidation levels of liver microsomes in various systems. Asperilin leads to a significant decrease in liver glutathione (GSH) levels and an increase in glutathione peroxidase (GPx) activity. Asperilin can be used for research on inflammatory conditions .

HY-D1395

RH-EDA	Reactive Oxygen Species (ROS)	Others
RH-EDA is a rhodamine-based turn-on fluorescent probe for detecting hydroxyl radicals in living systems.

HY-W007345

2-Amino-5-fluorophenol 4-Fluoro-2-hydroxyaniline	Biochemical Assay Reagents	Others
2-Amino-5-fluorophenol is an isomer of aminofluorophenol and also a HONO generator. 2-Amino-5-fluorophenol reacts with nitrogen dioxide (NO₂) via two pathways to form nitrous acid (HONO): hydrogen abstraction from the hydroxyl group and hydrogen abstraction from the amino group, with both the amino and hydroxyl groups participating in the reaction in the transition state .

HY-N7014

Hydroxyl-γ-isosanshool	Others	Neurological Disease
Hydroxyl-γ-isosanshool is one of the major alkylamides in Z. bungeanum and Z. schinifolium oils. Hydroxyl-γ-isosanshoo induces a numbing sensation .

HY-D1067

NIR dye-1	Fluorescent Dye	Others
NIR dye-1 (Compound 1h) is a near-infrared (NIR) fluorescent dye. NIR dye-1 has absorption and emission in the NIR region, while retaining an optically tunable hydroxyl group .

HY-W190921

t-Butyl 3-(hydroxypropoxyl)-propanoate	Biochemical Assay Reagents	Others
t-Butyl 3-(hydroxypropoxyl)-propanoate contains reactive hydroxyl and t-butyl protected carboxyl moieties. The hydroxyl group can react to further derivatize the compound. The t-butyl carbonyl group can be deprotected under acidic conditions.

HY-E70241

3-Hydroxypropionyl-CoA	Endogenous Metabolite	Others
3-Hydroxypropionyl-CoA is a derivative of coenzyme A containing a hydroxyl group .

HY-N15973

DSPE PEG2k-OH ammonium	Biochemical Assay Reagents	Others
DSPE PEG2k-OH ammonium is a hydroxyl-terminated PEGylated phospholipid. The hydrophobic tail allows for the encapsulation and aggregation of other hydrophobic drugs, and the hydroxyl terminus is suitable for further reactions. DSPE PEG2k-OH ammonium can be used to prepare liposomes or lipid nanoparticles .

HY-W142194

Benzyl (5-hydroxypentyl)carbamate	DNA/RNA Synthesis	Cancer
Benzyl (5-hydroxypentyl)carbamate is a linker capable of repairing damaged DNA by binding to the 5'-hydroxyl group on the sugar backbone. Benzyl (5-hydroxypentyl)carbamate can also bind to DNA ligands and can inhibit cell proliferation in resistant cell lines. However, Benzyl (5-hydroxypentyl)carbamate is toxic to cells and can also cause DNA damage and strand breakage.

HY-144245S

*5-Hydroxyl* ZLN005-d13**	Isotope-Labeled Compounds	Others
5-Hydroxyl ZLN005-d₁₃ is the deuterium labeled 5-Hydroxyl ZLN005 .

HY-N9961

*2-Hydroxyl* emodin-1-methyl ether**	Others	Others
2-Hydroxyl emodin-1-methyl ether (Compound 5) is an anthraquinone that can be isolated from the seeds of Cassia obtusifolia .

HY-N3289

Methyl 3,4,5-trimethoxycinnamate	Others	Others
Methyl 3,4,5-trimethoxycinnamate (Compound III) is a natural compound with hydroxyl radical-scavenging effects .

HY-107259

*23S-Hydroxyl-11,15-dioxo-ganoderic acid DM* 23S-Hydroxy-3,7,11,15-tetraoxo-lanost-8,24E-diene-26-oic	Others	Others
23S-Hydroxyl-11,15-dioxo-ganoderic acid DM is a compound isolated from the fruit bodies of Ganoderma lucidum .

HY-D0113

*7-Hydroxy-4-methyl-2(1H)-quinolone*	Reactive Oxygen Species (ROS)	Others
7-Hydroxy-4-methyl-2(1H)-quinolone (compound 2b) is a fluorescent hydroxylated product. 7-Hydroxy-4-methyl-2(1H)-quinolone can be used for detecting hydroxyl radicals of DNA damage .

HY-19129

KT2-962	Prostaglandin Receptor	Cardiovascular Disease
KT2-962 is a thromboxane A2 (TXA2) receptor antagonist and potent hydroxyl radical scavenger (IC₅₀=500 nM). KT2-962 reduces myocardial infarct size and ventricular fibrillation. KT2-962 demonstrates cardioprotective effect in a canine ischemia/reperfusion model. KT2-962 is promising for research of myocardial ischemia-reperfusion injury and TXA2-mediated vascular diseases .

HY-N9095

Curculigoside C	Others	Neurological Disease
Curculigoside C is a phenolic glucoside with potent antioxidative and neuroprotective activities. Curculigoside C shows IC₅₀ values of 0.25 mM and 0.88 mM for hydroxyl radicals and superoxide anion radicals, respectively .

HY-Y0958R

Methoxyamine hydrochloride (Standard) O-Methylhydroxylamine hydrochloride (Standard)	Reference Standards DNA/RNA Synthesis Apoptosis	Cancer
Methoxyamine hydrochloride (Standard) is the analytical standard of Methoxyamine hydrochloride. This product is intended for research and analytical applications. Methoxyamine (O-Methylhydroxylamine) hydrochloride is an orally active and potent base excision repair (BER) inhibitor. Methoxyamine hydrochloride binds to 3’ hydroxyl groups that are left behind by 3-methylpurine-DNA glycosylase (MPG) following excision of the damaged base and thus inhibits BER activity. Methoxyamine hydrochloride binds directly to the apyrimidinic (AP) sites. Methoxyamine hydrochloride synergistically enhances the therapeutic efficacy of DNA-damaging agents .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0828

Pterostilbene 5+ Cited Publications	Monophenols other families Stilbenes Classification of Application Fields Phenols Plants Inflammation/Immunology Disease Research Fields Source Classification	Autophagy
Pterostilbene is a stilbenoid isolated from blueberries and Pterocarpus marsupium . Shows anti-oxidant, anti-inflammatory, anti-carcinogenic, anti-diabetic and anti-obesity properties . Pterostilbene blocks ROS production , also exhibits inhibitory activity against various free radicals such as DPPH, ABTS, hydroxyl, superoxide and hydrogen peroxide .

HY-N7075

Inulin 4 Publications Verification	Structural Classification Human Gut Microbiota Metabolites Polysaccharides Classification of Application Fields Metabolic Disease Plants Compositae Endogenous metabolite Disease Research Fields Saccharides Sophora tomentosa L. Source Classification	Endogenous Metabolite
Inulin is an orally active prebiotic targeting the intestinal microbiota, selectively promoting the proliferation and activity of beneficial bacteria such as bifidobacteria and lactic acid bacteria, and playing a role in regulating the intestinal microecology. The functions of Inulin include: Fermentation by probiotics in the colon to produce short-chain fatty acids (such as butyrate and propionate), lowering the intestinal pH and inhibiting the overgrowth of harmful bacteria; Enhancing the intestinal barrier function and reducing endotoxin translocation; Directly scavenging free radicals (such as superoxide free radicals, hydroxyl free radicals) and activating antioxidant enzymes (SOD, CAT) to reduce oxidative stress. Inulin can also be used in the study of intestinal diseases (constipation, IBD), metabolic syndrome (diabetes, obesity) and liver damage by regulating glucose and lipid metabolism (such as reducing triglycerides, improving insulin sensitivity) and immune response (enhancing NK cell activity, inhibiting inflammatory factors)[1][2][3][4].

HY-N0499

Cyanidin Chloride 4 Publications Verification IdB 1027	Structural Classification Anthocyans Flavonoids other families Classification of Application Fields Anti-aging Phenols Polyphenols Plants Disease Research Fields Source Classification Cancer	Prostaglandin Receptor
Cyanidin Chloride (IdB 1027) is an orally active antioxidant and enzyme inhibitor. Cyanidin Chloride has IC₅₀ values of 90 μM and 60 μM against PGHS-1 and PGHS-2, respectively. Cyanidin Chloride exhibits excellent antioxidant and anti-inflammatory activities, scavenges free radicals, inhibits lipid peroxidation, and protects DNA from cleavage. Cyanidin Chloride can be used in the research of inflammatory diseases .

HY-113338

8-Hydroxyguanine 8-Oxoguanine; 8-oxo-Gua	Natural Products Immune System Disorder Classification of Application Fields Disease markers Other Diseases Endocrine diseases Nervous System Disorder Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
8-Hydroxyguanine is a DNA damage product under oxidative stress, which is formed when hydroxyl radicals attack guanine in DNA. 8-Hydroxyguanine induces mutagenesis and leads to a transversion from G to T. 8-Hydroxyguanine is a marker of DNA oxidative damage .

HY-W014423

L-Histidine hydrochloride hydrate 3 Publications Verification H-His-OH.HCl.H2O	Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite Apoptosis Reactive Oxygen Species (ROS)
L-Histidine hydrochloride hydrate is an endogenous metabolite. L-Histidine hydrochloride hydrate scavenges hydroxyl radicals and singlet oxygen, regulate the absorption of zinc, copper and iron, exhibits anti-inflammatory and antioxidant activities. L-Histidine hydrochloride hydrate is blood brain barrier penetrable .

HY-N13022

Humic acid 1 Publications Verification	Structural Classification Natural Products Plants Source Classification	Environmental Pollutants Bacterial SOD
Humic acid is an important component of organic matter in soil and water, and serves as a plant regulator. Humic acid has multiple reactive activities such as surface adsorption, ion exchange, and complexation. Humic acid can enhance pyrene degradation by Mycobacterium NJS-1. Humic acid can inhibit the activity of superoxide dismutase and scavenge hydroxyl radicals. Humic acid is also toxic to CEM cells .

HY-W027951

N,N'-Dimethylthiourea 1 Publications Verification DMTU	Structural Classification Natural Products Liliaceae Classification of Application Fields Allium sativum Linn. Plants Inflammation/Immunology Disease Research Fields Source Classification	Environmental Pollutants Reactive Oxygen Species (ROS)
N,N'-Dimethylthiourea (DMTU), isolated from Allium sativum, is an orally active scavenger of hydroxyl radical (•OH) and blocks •OH production by activated neutrophils in vitro. N,N'-Dimethylthiourea protects against water-immersion restraint stress (WIRS)-induced gastric mucosal lesions in rats by exerting its antioxidant action including •OH scavenging and anti-inflammatory action .

HY-N0448

10-Gingerol 4 Publications Verification	Zingiber officinale Roscoe Structural Classification Monophenols Classification of Application Fields Ketones, Aldehydes, Acids Phenols Plants Inflammation/Immunology Disease Research Fields Source Classification Zingiberaceae	AMPK Reactive Oxygen Species (ROS) Akt PI3K Interleukin Related TNF Receptor Apoptosis
10-Gingerol is an AMPK agonist, which is found in the ginger oleoresin from fresh rhizome with anti-inflammatory, antioxidant and anti-proliferative activities. 10-Gingerol suppresses neointimal hyperplasia and inhibits vascular smooth muscle cell proliferation. 10-Gingerol exhibits substantial scavenging activities with an IC₅₀ value of 10.47 μM against DPPH radical, an IC₅₀ value of 1.68 μM against superoxide radical and an IC₅₀ value of 1.35 μM against hydroxyl radical. 10-Gingerol inhibits the proliferation of MDA-MB-231 tumor cell line with an IC₅₀ of 12.1 μM. 10-Gingerol suppresses the proliferation, migration, invasion, and induced apoptosis through targeting the PI3K/Akt signaling pathway in MDA-MB-231/IR cells. 10-Gingerol can be used in research on various common cancers such as ovarian cancer and colon cancer, as well as colitis and neurodegenerative diseases .

HY-N4168A

Neochlorogenic acid methyl ester 5-O-Caffeoylquinic acid methyl ester	Structural Classification Caprifoliaceae Lonicera japonica Thunb. Phenols Polyphenols Plants Source Classification	Quinone Reductase HBV
Neochlorogenic acid (5-O-Caffeoylquinic) methyl ester is a selective quinone reductase inducer (EC₅₀ = 6.7 μM) and also exhibits hydroxyl radical scavenging activity (EC₅₀ = 0.81 μM). Neochlorogenic acid methyl ester scavenges hydroxyl radicals by donating electrons or hydrogen atoms, while simultaneously inducing quinone reductase expression to enhance carcinogen detoxification, thus exerting antioxidant and cancer chemopreventive activities. Neochlorogenic acid methyl ester is used in research on antioxidant damage and promoting detoxification metabolism, primarily in the fields of cancer chemotherapy and antioxidant-related diseases. Neochlorogenic acid methyl ester is also an HBV inhibitor and can be isolated from the flower buds of L. japonica .

HY-107486

Nosiheptide Multhiomycin; RP 9671	Infection Microorganisms Antibiotics Animal Husbandry Antibacterial Disease Research Disease Research Fields Other Antibiotics Source Classification	Bacterial Antibiotic
Nosiheptide (Multhiomycin), a thiopeptide antibiotic produced by Streptomyces actuosus, inhibits bacterial protein synthesis and bears a unique indole side ring system and regiospecific hydroxyl groups on the characteristic macrocyclic core. Nosiheptide has been widely used as a feed additive for animal growth .

HY-N9497

Galactinol	Source Classification	Galectin Fungal
Galactinol is a disaccharide carbohydrate serving as a galactosyl donor, which belongs to the raffinose family oligosaccharide pathway and acts as an important osmoprotectant. Galactinol not only induces disease resistance in plants against fungal and bacterial pathogens, but also significantly enhances plant tolerance to abiotic stresses such as drought, high salinity, low temperature and oxidative damage. In addition, Galactinol has the ability to *scavenge hydroxyl* radicals**, can act as a signaling component for root colonization-induced systemic resistance, and is positively correlated with seed longevity in various crops, making it a potential biomarker for evaluating seed vigor. Therefore, Galactinol can be used in the research of various plant diseases including fungal leaf spot, bacterial angular leaf spot, gray mold and soft rot .

HY-134222A

N-Acetylserine N-Acetyl-L-serine	Structural Classification Natural Products Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite Complement System
N-Acetylserine (N-Acetyl-L-serine) is a complement pathway modulator targeting activated third complement protein (C3b) and an amino-terminal residue (an N-terminal acetylation modification group). N-Acetylserine reacts with the exposed thioester group of C3b via its hydroxyl group, thereby blocking the covalent binding of glycerol to this thioester group. N-Acetylserine widely exists in soluble proteins of mammalian cells (accounting for approximately 80% of such proteins). N-Acetylserine has a blocking property that prevents direct Edman sequencing of proteins; deblocking is achievable through trifluoroacetic acid-catalyzed N→O acetyl migration followed by β-elimination. N-Acetylserine is suitable for sequencing of proteins with N-terminal acetylserine modification .

HY-N2436

2,3-Dihydroxysuccinic acid Tartaric acid	Human Gut Microbiota Metabolites Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Biochemical Assay Reagents
2,3-Dihydroxysuccinic acid (Tartaric acid) is an organic acid containing two hydroxyl groups and two carboxyl groups. 2,3-Dihydroxysuccinic acid exists in various stereoisomers and is widely used in food, pharmaceutical, chemical, and other fields .

HY-Y0801

2,6-Dihydroxybenzoic acid	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Phenols Polyphenols Endogenous metabolite Disease Research Fields Source Classification	Drug Metabolite
2,6-Dihydroxybenzoic acid is an aromatic compound containing phenolic hydroxyl groups and carboxyl groups, and it is a secondary metabolite of Salicylic acid (HY-B0167). 2,6-Dihydroxybenzoic acid is also present in olive oil wastewater .

HY-105055

Didemnin B	Natural Products Animals Classification of Application Fields Marine natural products Other marine organisms Disease Research Fields Source Classification Cancer	Others
Didemnin B is a depsipeptide extracted from the marine tunicate Trididemnin cyanophorum. Didemnin B can be used for the research of cancer .

HY-W015788

1-Phenylethane-1,2-diol Styrene Glycol	Structural Classification Natural Products Microorganisms Classification of Application Fields Other Diseases Disease Research Fields	Environmental Pollutants Drug Metabolite Biochemical Assay Reagents
1-Phenylethane-1,2-diol (Styrene Glycol) is a benzyl diol compound, which is the major metabolite of Styrene. 1-Phenylethane-1,2-diol can be oxidized to hydroxyl ketone (2-hydroxy-1-phenylethan-1-one) selectively with variety of catalysts, including organocatalysts, metal complexes, non-noble metal oxides, bimetallics .

HY-W047187

Lavandoside	Structural Classification other families Onychium japonicum (Thunb.) Kunze Ketones, Aldehydes, Acids Plants	Xanthine Oxidase NO Synthase TNF Receptor
Lavandoside is an ABTS ^?+ free radical scavenger and a moderate inhibitor of xanthine oxidase (XO), with an IC₅₀ of 71.6 μM for inhibiting NO production in LPS-induced macrophages. Lavandoside exerts its antioxidant and potential anti-inflammatory effects by directly scavenging free radicals and inhibiting XO activity, a mechanism related to the hydroxyl groups in its molecular structure. Lavandoside can be isolated from lavender and can be used in the development of natural antioxidants and in research on oxidative stress-related diseases and inflammation-related diseases .

HY-N0627

Kaempferol-7-O-β-D-glucopyranoside	Flavonols Structural Classification Flavonoids other families Classification of Application Fields Phenols Polyphenols Plants Inflammation/Immunology Disease Research Fields Source Classification	LDLR
Kaempferol-7-O-β-D-glucopyranoside is a flavonoid glycoside. Kaempferol-7-O-β-D-glucopyranoside exists in the root bark of Cudrania tricuspidata. Kaempferol-7-O-β-D-glucopyranoside inhibits Cu ²⁺-induced lipid peroxidation of low-density lipoprotein. Kaempferol-7-O-β-D-glucopyranoside possesses antioxidant activity and scavenges DPPH free radicals .

HY-151852

9AzNue5Ac	Cardiovascular Disease Natural Products Classification of Application Fields Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
9AzNue5Ac, 9-azido-9-deoxy-N-acetylneuraminic acid, is a click chemistry reagent and a Neu5Ac analogue with the substitution of 9-hydroxyl group with an azide. 9AzNue5Ac could be metabolized and incorporated into sialoglycans in living cells and mice. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-W345885

Saccharic acid	Human Gut Microbiota Metabolites Endogenous metabolite Source Classification	β-glucuronidase
Saccharic acid is a competitive and potent inhibitor of β-glucuronidase. Saccharic acid inhibits glucuronide synthesis. Saccharic acid as an efficient iron chelate to enhance photo-Fenton degradation of organic contaminants .

HY-W015936

(E)-Hex-2-en-1-ol trans-Hex-2-en-1-ol	Source Classification	Environmental Pollutants Biochemical Assay Reagents
(E)-Hex-2-en-1-ol belongs to the class of unsaturated alcohols consisting of a six-carbon chain with a double bond between carbon atoms 2 and 3 and a hydroxyl group attached to carbon atom 1. The compound has a grassy or herbaceous smell and is commonly used as a flavoring in foods such as baked goods, candy and beverages. It can also be used as a fragrance ingredient in personal care products and as a starting material for the synthesis of other organic compounds. Furthermore, (E)-hex-2-en-1-ol can be used as a solvent or reagent in various chemical reactions.

HY-N3847

Eriodictyol-7-O-glucoside Eriodictyol 7-O-β-D-glucoside	Flavonoids Classification of Application Fields Labiatae Flavonones Phenols Polyphenols Metabolic Disease Plants Disease Research Fields Petalostemun purpureum Source Classification	Keap1-Nrf2
Eriodictyol-7-O-glucoside (Eriodictyol 7-O-β-D-glucoside), a flavonoid, is an Nrf2 activator. Eriodictyol-7-O-glucoside exhibits significant scavenging effects on both hydroxyl radicals and superoxide anions, with IC₅₀ values of 0.28 mM and 0.30 mM, respectively. Eriodictyol-7-O-glucoside increases the nuclear localization of Nrf2 and induces the expression of the Nrf2/ARE-dependent genes. Eriodictyol-7-O-glucoside provides protection against oxygen and glucose deprivation (OGD)-induced oxidative insult. Eriodictyol-7-O-glucoside demonstrates neuroprotective efficacy in a rat model of focal cerebral ischemia (MCAO). Eriodictyol-7-O-glucoside can be used for the study of stroke .

HY-N6964

Quercetin 3-O-β-D-(6''-p-coumaroyl)glucopyranosyl(1→2)-α-L-rhamnopyranoside Quercetin-3-O-[2-O-(6-O-p-hydroxyl-E-coumaroyl)-D-glucosyl]-(1→2)-L-rhamnoside	Flavonols Flavonoids Classification of Application Fields Ginkgoaceae Phenols Polyphenols Metabolic Disease Plants Disease Research Fields Ginkgo biloba Source Classification	Others
Quercetin 3-O-β-D-(6''-p-coumaroyl)glucopyranosyl(1→2)-α-L-rhamnopyranoside (Quercetin-3-O-[2-O-(6-O-p-hydroxyl-E-coumaroyl)-D-glucosyl]-(1→2)-L-rhamnoside) is one of the major antioxidants of Ginkgo biloba leaves .

HY-W004289

Methyl pentadecanoate	Structural Classification other families Classification of Application Fields Other Diseases Plants Disease Research Fields Lipid Source Classification	Drug Derivative
Methyl pentadecanoate is a fatty acid ester that can be isolated from extracts of L. wallichi. Methyl pentadecanoate is formed by the condensation of the carboxyl group of pentadecanoic acid with the hydroxyl group of methanol .

HY-W021265

Cyclohexane-1,2,3,4,5,6-hexaol Cyclohexane-1,2,3,4,5,6-hexol	Microorganisms Source Classification	Biochemical Assay Reagents
Cyclohexane-1,2,3,4,5,6-hexaol, also known as inositol or inositol, is a cyclic sugar alcohol consisting of a six-carbon ring with six hydroxyl groups. This compound is important for its biological activity and is widely distributed in nature, especially in plant and animal tissues. It plays a role in various physiological processes such as signal transduction, osmoregulation and lipid metabolism. In addition, Cyclohexane-1,2,3,4,5,6-hexaol has potential investigational effects, including improving conditions related to insulin resistance, polycystic ovary syndrome, and mental health conditions. It can also be used as a supplement in animal feed and human nutritional products.

HY-N0499A

Cyanidin	Structural Classification Caprifoliaceae Phenols Polyphenols Sambucus williamsii Hance Plants Source Classification	Prostaglandin Receptor
Cyanidin is an orally active antioxidant and enzyme inhibitor. Cyanidin has IC₅₀ values of 90 μM and 60 μM against PGHS-1 and PGHS-2, respectively. Cyanidin exhibits excellent antioxidant and anti-inflammatory activities, scavenges free radicals, inhibits lipid peroxidation, and protects DNA from cleavage. Cyanidin can be used in the research of inflammatory diseases .

HY-N2625A

Harmalol hydrochloride	Alkaloids Monophenols Classification of Application Fields Zygophyllaceae Peganum harmala Linn. Other Diseases Phenols Pyridine Alkaloids Plants Disease Research Fields Source Classification	Cytochrome P450
Harmalol hydrochloride, a beta carboline alkaloid, presents in several medicinal plants such as Peganum harmala. Harmalol hydrochloride, main metabolite of Harmaline, significantly inhibits the dioxin-mediated induction of CYP1A1 at the transcriptional and posttranslational levels. Harmalol hydrochloride possesses antioxidant and hydroxyl radical-scavenging properties .

HY-W021267

3-Demethylcolchicine	Alkaloids Structural Classification Monophenols other families Classification of Application Fields Other Alkaloids Phenols Plants Inflammation/Immunology Disease Research Fields Source Classification	Reactive Oxygen Species (ROS)
3-Demethylcolchicine, a colchicine metabolite and anti-inflammatory agent, exhibits potent tubulin-binding activity. 3-Demethylcolchicine inhibits carrageenan-induced rat paw edema. 3-Demethylcolchicine bears a hydroxyl group on its carbocyclic ring; this group participates in free radical scavenging processes, allowing it to act as a free radical scavenger. 3-Demethylcolchicine is applicable to studies related to carrageenan-induced paw edema .

HY-N0674B

*Dehydrocorydaline (hydroxyl)* Maximum Cited Publications 43 Publications Verification 13-Methylpalmatine (hydroxyl)	Alkaloids Corydalis yanhusuo W. T. Wang Plants Papaveraceae Source Classification	Bcl-2 Family Caspase PARP p38 MAPK Parasite Autophagy
Dehydrocorydaline (13-Methylpalmatine) hydroxyl is an alkaloid that regulates protein expression of Bax, Bcl-2; activates caspase-7, caspase-8, and inactivates PARP. Dehydrocorydaline hydroxyl elevates p38 MAPK activation. Anti-inflammatory and anti-cancer activities. Dehydrocorydaline hydroxyl shows strong anti-malarial effects (IC50=38 nM), and low cytotoxicity (cell viability > 90%) using P. falciparum 3D7 strain.

HY-N2627

Isorhamnetin 3-O-robinobioside	Structural Classification Flavonols Flavonoids Cactaceae Opuntia ficus-indica (L.) Mill. Plants Source Classification	Others
Isorhamnetin 3-O-robinobioside is a flavonoid compound. Isorhamnetin shows a protective effect against lipid peroxidation induced by H₂O₂. Isorhamnetin 3-O-robinobioside also inhibits the genotoxicity induced by hydroxyl radicals .

HY-N7935

Procyanidin B5	Structural Classification Aronia melanocarpa Rosaceae Phenols Polyphenols Plants Source Classification	Reactive Oxygen Species (ROS)
Procyanidin B5 is an antioxidant with a IC₅₀ of 0.1 mM in lipid peroxidation assays using mouse liver homogenates. Procyanidin B5 scavenges superoxide anions and hydroxyl radicals, and inhibits lipid peroxidation. Procyanidin B5 can be used in research related to cardiovascular diseases, cancer, and malaria .

HY-N0828R

Pterostilbene (Standard)	Structural Classification Monophenols other families Stilbenes Phenols Plants Source Classification	Reference Standards Autophagy
Pterostilbene (Standard) is the analytical standard of Pterostilbene. This product is intended for research and analytical applications. Pterostilbene is a stilbenoid isolated from blueberries and Pterocarpus marsupium . Shows anti-oxidant, anti-inflammatory, anti-carcinogenic, anti-diabetic and anti-obesity properties . Pterostilbene blocks ROS production , also exhibits inhibitory activity against various free radicals such as DPPH, ABTS, hydroxyl, superoxide and hydrogen peroxide .

HY-W015229R

3-Indolepropionic acid (Standard) Indole-3-propionic acid (Standard); 3-IPA (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite Reactive Oxygen Species (ROS)
3-Indolepropionic acid (Standard) is the analytical standard of 3-Indolepropionic acid. This product is intended for research and analytical applications. 3-Indolepropionic acid is shown to be a powerful antioxidant and has potential in the treatment for Alzheimer’s disease. In Vitro: 3-Indolepropionic acid is shown to be a powerful antioxidant and has potential in the treatment for Alzheimer’s disease . 3-Indolepropionic acid is a more potent scavenger of hydroxyl radicals than melatonin. Similar to melatonin but unlike other antioxidants, 3-Indolepropionic acid scavenges radicals without subsequently generating reactive and pro-oxidant intermediate compounds . It is also suggested that indolepropionic acid, a gut microbiota-produced metabolite, is a potential biomarker for the development of type 2 diabetes (T2D) that may mediate its protective effect by preservation of β-cell function .

HY-W007671

H-Tyr-OMe 1 Publications Verification	Monophenols Classification of Application Fields Other Diseases Phenols Amino acids Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite Tyrosinase
H-Tyr-OMe is an endogenous metabolite. H-Tyr-OMe quenches the fluorescence of carbon dots by oxidizing the phenolic hydroxyl group to quinone under the catalysis of Tyrosinase, and its amino and thiol binding ability can respond to changes in the concentration of biothiols .

HY-107486R

Nosiheptide (Standard) Multhiomycin (Standard); RP 9671 (Standard)	Structural Classification Microorganisms Antibiotics Animal Husbandry Antibacterial Disease Research Other Antibiotics Source Classification	Reference Standards Bacterial Antibiotic
Nosiheptide (Standard) is the analytical standard of Nosiheptide. This product is intended for research and analytical applications. Nosiheptide (Multhiomycin), a thiopeptide antibiotic produced by Streptomyces actuosus, inhibits bacterial protein synthesis and bears a unique indole side ring system and regiospecific hydroxyl groups on the characteristic macrocyclic core. Nosiheptide has been widely used as a feed additive for animal growth .

HY-134493

Butyrate-Vitamin D3 Butyrate-Cholecalciferol; Butyrate-Colecalciferol	Natural Products Endogenous metabolite Source Classification	VD/VDR
Butyrate-Vitamin D3 (Butyrate-Cholecalciferol) is a derivative of vitamin D3 in which a hydroxyl group in the vitamin D3 molecule is replaced by a butyric acid group. Butyrate-Vitamin D3 affects gene expression and cell function and has certain anti-inflammatory effects. Butyrate-Vitamin D3 can be used in the study of immune regulation, metabolic diseases and cancer .

HY-E70007

Catechol O-methyltransferase, porcine liver COMT	Natural Products Neurological Disease Classification of Application Fields Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Catechol O-methyltransferase, porcine liver (COMT), the magnesium-dependent transfer of methyl groups from S-adenosyl methionine to a hydroxyl group on dopamine, converting it to 3-methoxytyramine. Catechol O-methyltransferase has two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). Catechol O-methyltransferase is to regulate epinephrine, norepinephrine, and dopamine levels in the brain .

HY-N16658

Asperilin NSC 85238	Structural Classification Terpenoids Sesquiterpenes Plants Compositae Oparanthus teikiteetinii (J.Florence & Stuessy) R.K.Shannon & W.L.Wagner Source Classification	Glutathione Peroxidase
Asperilin (NSC 85238) is an orally active sesquiterpene lactone. Asperilin is an effective hydroxyl radical scavenger. Asperilin significantly enhance the lipid peroxidation levels of liver microsomes in various systems. Asperilin leads to a significant decrease in liver glutathione (GSH) levels and an increase in glutathione peroxidase (GPx) activity. Asperilin can be used for research on inflammatory conditions .

HY-N2436R

2,3-Dihydroxysuccinic acid (Standard) Tartaric acid (Standard)	Structural Classification Human Gut Microbiota Metabolites Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Biochemical Assay Reagents Reference Standards
2,3-Dihydroxysuccinic acid (Standard) (Tartaric acid (Standard)) is the analytical standard of 2,3-Dihydroxysuccinic acid (HY-N2436). This product is intended for research and analytical applications. 2,3-Dihydroxysuccinic acid (Tartaric acid) is an organic acid containing two hydroxyl groups and two carboxyl groups. 2,3-Dihydroxysuccinic acid exists in various stereoisomers and is widely used in food, pharmaceutical, chemical, and other fields.

HY-W017241

1-Naphthalenemethanol 1-Hydroxymethylnaphthalene	Structural Classification Natural Products Microorganisms other families Classification of Application Fields Plants Inflammation/Immunology Disease Research Fields Source Classification	Bacterial Biochemical Assay Reagents
1-Naphthalenemethanol is a hydroxyl-substituted naphthalene derivative. 1-Naphthalenemethanol can be extracted from the root of Annona senegalensis. 1-Naphthalenemethanol is a photolysis product of 1-napthaleneacetic acid. 1-Naphthalenemethanol, together with PAPS, provides some protection against the irreversible inactivation of AST IV caused by N-OH-2AF. 1-Naphthalenemethanol can be used in antibacterial research .

HY-N7014

Hydroxyl-γ-isosanshool	Natural Products Myrtaceae Plants Syzygium aromaticum Source Classification	Others
Hydroxyl-γ-isosanshool is one of the major alkylamides in Z. bungeanum and Z. schinifolium oils. Hydroxyl-γ-isosanshoo induces a numbing sensation .

HY-N15973

DSPE PEG2k-OH ammonium	Lipid	Biochemical Assay Reagents
DSPE PEG2k-OH ammonium is a hydroxyl-terminated PEGylated phospholipid. The hydrophobic tail allows for the encapsulation and aggregation of other hydrophobic drugs, and the hydroxyl terminus is suitable for further reactions. DSPE PEG2k-OH ammonium can be used to prepare liposomes or lipid nanoparticles .

HY-N16396

Ampelanol	Quinones Microorganisms Anthraquinones Source Classification	Drug Derivative
Ampelanol is a derivative of Altersolanol A (HY-125461). Ampelanol has no anticancer and anti-inflammatory activity through the reduction of one of a carbonyl group and removal of hydroxyl substituents within Altersolanol A. Ampelanol can be used as a negative control .

HY-N0448R

10-Gingerol (Standard)	Zingiber officinale Roscoe Structural Classification Natural Products Monophenols Phenols Plants Source Classification Zingiberaceae	Reference Standards Others
10-Gingerol (Standard) is the analytical standard of 10-Gingerol (HY-N0448). This product is intended for research and analytical applications. 10-Gingerol is an AMPK agonist, which is found in the ginger oleoresin from fresh rhizome with anti-inflammatory, antioxidant and anti-proliferative activities. 10-Gingerol suppresses neointimal hyperplasia and inhibits vascular smooth muscle cell proliferation. 10-Gingerol exhibits substantial scavenging activities with an IC₅₀ value of 10.47 μM against DPPH radical, an IC₅₀ value of 1.68 μM against superoxide radical and an IC₅₀ value of 1.35 μM against hydroxyl radical. 10-Gingerol inhibits the proliferation of MDA-MB-231 tumor cell line with an IC₅₀ of 12.1 μM. 10-Gingerol suppresses the proliferation, migration, invasion, and induced apoptosis through targeting the PI3K/Akt signaling pathway in MDA-MB-231/IR cells. 10-Gingerol is promising for research of ulcerative colitis .

HY-N9961

*2-Hydroxyl* emodin-1-methyl ether**	Quinones Anthraquinones Caesalpiniaceae Cassia obtusifolia (L.) H. S. Irwin & Barneby Plants Source Classification	Others
2-Hydroxyl emodin-1-methyl ether (Compound 5) is an anthraquinone that can be isolated from the seeds of Cassia obtusifolia .

HY-N3289

Methyl 3,4,5-trimethoxycinnamate	Natural Products Plants Brassicaceae Source Classification Mutarda nigra (L.) Bernh.	Others
Methyl 3,4,5-trimethoxycinnamate (Compound III) is a natural compound with hydroxyl radical-scavenging effects .

HY-107259

*23S-Hydroxyl-11,15-dioxo-ganoderic acid DM* 23S-Hydroxy-3,7,11,15-tetraoxo-lanost-8,24E-diene-26-oic	Triterpenes Classification of Application Fields Terpenoids Polyporaceae Other Diseases Plants Disease Research Fields Source Classification	Others
23S-Hydroxyl-11,15-dioxo-ganoderic acid DM is a compound isolated from the fruit bodies of Ganoderma lucidum .

HY-N9095

Curculigoside C	Curculigo orchioides Gaertn. Phenols Polyphenols Plants Amaryllidaceae Source Classification	Others
Curculigoside C is a phenolic glucoside with potent antioxidative and neuroprotective activities. Curculigoside C shows IC₅₀ values of 0.25 mM and 0.88 mM for hydroxyl radicals and superoxide anion radicals, respectively .

HY-N9332

Kalopanax saponin G	Triterpenes Structural Classification Classification of Application Fields Terpenoids Kalopanax septemlobus (Thunb.) Koidz. Other Diseases Plants Pentacyclic Triterpenoids Disease Research Fields Araliaceae Source Classification	Others
Kalopanax saponin G is an ester glycoside of oleanolic acid possessing no sugar moiety at the C-3 hydroxyl group. Kalopanax saponin G is isolated from the bark of Kalopanax pictus .

HY-W007671R

H-Tyr-OMe (Standard)	Monophenols Phenols Amino acids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite Tyrosinase
H-Tyr-OMe is an endogenous metabolite. H-Tyr-OMe quenches the fluorescence of carbon dots by oxidizing the phenolic hydroxyl group to quinone under the catalysis of Tyrosinase, and its amino and thiol binding ability can respond to changes in the concentration of biothiols .

Cat. No.	Product Name	Chemical Structure

HY-W014423S2

L-Histidine-13C6 hydrochloride hydrate

L-Histidine- ¹³C₆ (hydrochloride hydrate) is the ¹³C-labeled L-Histidine hydrochloride hydrate (HY-W014423). L-Histidine hydrochloride hydrate is an endogenous metabolite. L-Histidine hydrochloride hydrate scavenges hydroxyl radicals and singlet oxygen, regulate the absorption of zinc, copper and iron, exhibits anti-inflammatory and antioxidant activities. L-Histidine hydrochloride hydrate is blood brain barrier penetrable .

HY-W014423S3

L-Histidine-13C6,15N3 hydrochloride hydrate

L-Histidine- ¹³C₆, ¹⁵N₃ hydrochloride hydrate is the ¹³C- and ¹⁵N-labeled L-Histidine hydrochloride hydrate (HY-W014423). L-Histidine hydrochloride hydrate is an endogenous metabolite. L-Histidine hydrochloride hydrate scavenges hydroxyl radicals and singlet oxygen, regulate the absorption of zinc, copper and iron, exhibits anti-inflammatory and antioxidant activities. L-Histidine hydrochloride hydrate is blood brain barrier penetrable .

HY-W014423S4

L-Histidine-d5 hydrochloride hydrate

L-Histidine-d₅ hydrochloride hydrate is the deuterium labeled L-Histidine hydrochloride hydrate (HY-W014423). L-Histidine hydrochloride hydrate is an endogenous metabolite. L-Histidine hydrochloride hydrate scavenges hydroxyl radicals and singlet oxygen, regulate the absorption of zinc, copper and iron, exhibits anti-inflammatory and antioxidant activities. L-Histidine hydrochloride hydrate is blood brain barrier penetrable .

HY-W014423S6

L-Histidine-15N hydrochloride hydrate

L-Histidine- ¹⁵N hydrochloride hydrate is the ¹⁵N-labeled L-Histidine hydrochloride hydrate (HY-W014423). L-Histidine hydrochloride hydrate is an endogenous metabolite. L-Histidine hydrochloride hydrate scavenges hydroxyl radicals and singlet oxygen, regulate the absorption of zinc, copper and iron, exhibits anti-inflammatory and antioxidant activities. L-Histidine hydrochloride hydrate is blood brain barrier penetrable .

HY-W014423S

L-Histidine-13C hydrochloride hydrate

L-Histidine- ¹³C hydrochloride hydrate is the ¹³C-labeled L-Histidine hydrochloride hydrate (HY-W014423). L-Histidine hydrochloride hydrate is an endogenous metabolite. L-Histidine hydrochloride hydrate scavenges hydroxyl radicals and singlet oxygen, regulate the absorption of zinc, copper and iron, exhibits anti-inflammatory and antioxidant activities. L-Histidine hydrochloride hydrate is blood brain barrier penetrable .

HY-114296S

2,3-Oxidosqualene-d6

2,3-Oxidosqualene-d₆ (Squalene oxide-d₆) is a deuterium labeled 2,3-Oxidosqualene (HY-114296). 2,3-Oxidosqualene (Squalene oxide) is a sterol biosynthesis precursor intermediate.2,3-Oxidosqualene participates in cyclization pathways that form sterols and triterpenes, and contributes to introduction of their characteristic 3-hydroxyl group.2,3-Oxidosqualene forms metabolically from squalene in rat liver homogenates under sterol synthesis conditions.2,3-Oxidosqualene converts to sterols including cholesterol, lathosterol, and lanost-8-en-3β-ol in rat liver homogenates under anaerobic conditions.

HY-W014423S7

L-Histidine-d3 hydrochloride hydrate

L-Histidine-d₃ hydrochloride hydrate is the deuterium labeled L-Histidine hydrochloride hydrate (HY-W014423). L-Histidine hydrochloride hydrate is an endogenous metabolite. L-Histidine hydrochloride hydrate scavenges hydroxyl radicals and singlet oxygen, regulate the absorption of zinc, copper and iron, exhibits anti-inflammatory and antioxidant activities. L-Histidine hydrochloride hydrate is blood brain barrier penetrable .

HY-W014423S1

L-Histidine-13C6,15N3,d5 hydrochloride hydrate

L-Histidine- ¹³C₆, ¹⁵N₃,d₅ hydrochloride hydrate is the deuterium, ¹³C-, and 15-labeled L-Histidine hydrochloride hydrate (HY-W014423). L-Histidine hydrochloride hydrate is an endogenous metabolite. L-Histidine hydrochloride hydrate scavenges hydroxyl radicals and singlet oxygen, regulate the absorption of zinc, copper and iron, exhibits anti-inflammatory and antioxidant activities. L-Histidine hydrochloride hydrate is blood brain barrier penetrable .

HY-144245S

*5-Hydroxyl* ZLN005-d13**
5-Hydroxyl ZLN005-d₁₃ is the deuterium labeled 5-Hydroxyl ZLN005 .

HY-W710400

Quifenadine-d10
Quifenadine-d₁₀ is the deuterium labeled Quifenadine (HY-122761). Quifenadine (Compound 3a), the hydroxyl-(diphenyl)methyl quinuclidine derivative, is a M3 receptor antagonist with an IC₅₀ value > 1000 nM. Quifenadine can be used for the research of neurological disease .

HY-B0684S

Iopamidol-d8
Iopamidol-d₈ (B-15000-d₈) is the deuterium labeled Iopamidol. Iopamidol is a nonionic, X-Ray iodinated contrast agent (CA) for a wide variety of diagnostic applications. Iopamidol contains amide and hydroxyl functionalities that can be exploited for the generation of the chemical exchange saturation transfer (CEST) contrast .

HY-118830S1

13,14-Dihydro-15-keto prostaglandin D2-d9

13,14-Dihydro-15-keto prostaglandin D2-d₉ (DK-PGD2-d₉) is deuterium labeled 13,14-Dihydro-15-keto prostaglandin D2. 13, 14-Dihydro-15-keto prostaglandin D2 (DK-PGD2) is a PGD2 metabolite formed by the 15-hydroxyl PGDH pathway. 13, 14-Dihydro-15-keto prostaglandin D2 is a selective agonist for the DP2 receptor. 13, 14-Dihydro-15-keto prostaglandin D2 can inhibit ion flux in canine colonic mucosa preparation .

HY-W014423S5

L-Histidine-15N3 hydrochloride hydrate

L-Histidine- ¹⁵N₃ hydrochloride hydrate is the ¹⁵N-labeled L-Histidine hydrochloride hydrate (HY-W014423). L-Histidine hydrochloride hydrate is an endogenous metabolite. L-Histidine hydrochloride hydrate scavenges hydroxyl radicals and singlet oxygen, regulate the absorption of zinc, copper and iron, exhibits anti-inflammatory and antioxidant activities. L-Histidine hydrochloride hydrate is blood brain barrier penetrable .

HY-W014423S8

L-Histidine-15N3,d5 hydrochloride hydrate

L-Histidine- ¹⁵N₃,d₅ hydrochloride hydrate is the deuterium and ¹⁵N labeled L-Histidine hydrochloride hydrate (HY-W014423). L-Histidine hydrochloride hydrate is an endogenous metabolite. L-Histidine hydrochloride hydrate scavenges hydroxyl radicals and singlet oxygen, regulate the absorption of zinc, copper and iron, exhibits anti-inflammatory and antioxidant activities. L-Histidine hydrochloride hydrate is blood brain barrier penetrable .

HY-B0684S1

Iopamidol-d3
Iopamidol-d₃ (B-15000-d₃; SQ-13396-d₃) is the deuterium labeled Iopamidol (HY-B0684). Iopamidol is a nonionic, X-Ray iodinated contrast agent (CA) for a wide variety of diagnostic applications. Iopamidol contains amide and hydroxyl functionalities that can be exploited for the generation of the chemical exchange saturation transfer (CEST) contrast .

HY-W010505S

Hexane-1,6-diol-d4
Hexane-1,6-diol-d₄ is the deuterium labeled Hexane-1,6-diol (HY-W010505). Hexane-1,6-diol is a 6-carbon straight-chain diol with hydroxyl groups at both ends. Hexane-1,6-diol can be used as an additive for drilling fluids. Hexane-1,6-diol can also be used as a substrate in life science-related research .

HY-118830S

13,14-Dihydro-15-keto prostaglandin D2-d4

13,14-Dihydro-15-keto prostaglandin D2-d₄ (DK-PGD2-d₄) is deuterium labeled 13,14-Dihydro-15-keto prostaglandin D2. 13, 14-Dihydro-15-keto prostaglandin D2 (DK-PGD2) is a PGD2 metabolite formed by the 15-hydroxyl PGDH pathway. 13, 14-Dihydro-15-keto prostaglandin D2 is a selective agonist for the DP2 receptor. 13, 14-Dihydro-15-keto prostaglandin D2 can inhibit ion flux in canine colonic mucosa preparation .

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