226 Results for "

ionization

" in MedChemExpress (MCE) Product Catalog:
Products (226)

226 Results for "ionization" in MCE Product Catalog:

168
168 Publications Verification
Art. -Nr.: HY-112251
CAS. Nr.: 1224606-06-7
Reinheit:  99.68%
D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle.
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20
20 Cited Publications
Art. -Nr.: HY-145405
CAS. Nr.: 1220890-25-4
Reinheit:  99.91%
C12-200 is a type of ionizable cationic lipid and helper lipid commonly used for mRNA delivery. In the hemophilia B mouse model, mRNA encoding human erythropoietin (EPO) and coagulation factor IX (FIX) can be successfully delivered and expressed using C12-200. C12-200 is utilized in research related to hemophilia B .
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15
15 Cited Publications
Art. -Nr.: HY-13767
CAS. Nr.: 27314-97-2
Reinheit:  99.02%
Synonyms: SR259075; SR4233; Win59075; SML 0552; SR 259075; Tirazone
Target:  

DNA/RNA Synthesis

Forschungsgebiete:  

Cancer

Tirapazamine (SR259075) is an anticancer agent that shows selective cytotoxicity for hypoxic cells in solid tumors, thereby inducing single-and double-strand breaks in DNA, base damage, and cell death. Tirapazamine is an anticancer and bioreductive agent.Tirapazamine (SR259075) can enhance the cytotoxic effects of ionizing radiation in hypoxic cells .
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13
13 Cited Publications
Art. -Nr.: HY-107641
CAS. Nr.: 28166-41-8
Reinheit:  99.92%
Synonyms: α-Cyano-4-hydroxycinnamate
Forschungsgebiete:  

Metabolic Disease

α-Cyano-4-hydroxycinnamic acid (α-Cyano-4-hydroxycinnamate) is a potent and non-competitive inhibitor of monocarboxylate transporters (MCTs). α-Cyano-4-hydroxycinnamic acid inhibits mitochondrial pyruvate transporter with a Ki of 6.3 μM. α-Cyano-4-hydroxycinnamic acid is used as a matrix to facilitate peptide ionization in matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry applications .
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6
6 Cited Publications
Art. -Nr.: HY-129460
CAS. Nr.: 866404-31-1
Reinheit:  99.15%
Forschungsgebiete:  

Neurological Disease

XJB-5-131 is a mitochondria-targeted ROS and electron scavenger . XJB-5-131 is a bi-functional antioxidant that comprises a radical scavenger. XJB-5-131 is a synthetic antioxidant that targets mitochondria . XJB-5-131 is an effective ionizing irradiation protector and mitigator of cord blood mononuclear cells (CB MNCs) .
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5
5 Cited Publications
Art. -Nr.: HY-N0232
CAS. Nr.: 18642-23-4
Psoralidin is a dual inhibitor of COX-2 and 5-LOX, regulates ionizing radiation (IR)-induced pulmonary inflammation.Anti-cancer, anti-bacterial, and anti-inflammatory properties . Psoralidin significantly downregulates NOTCH1 signaling. Psoralidin also greatly induces ROS generation .
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5
5 Cited Publications
Art. -Nr.: HY-134781
CAS. Nr.: 1432494-65-9
Reinheit:  ≥98.0%
CKK-E12 is a ionizable lipid in combination with other lipids make up the lipid nanoparticles which are used to deliver RNA-based research. CKK-E12 is highly selective toward liver parenchymal cell in vivo,
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3
3 Cited Publications
Art. -Nr.: HY-112757
CAS. Nr.: 871258-12-7
Reinheit:  99.02%
DLinDMA, a ionizable cationic lipid, is a key lipid component of stable nucleic acid lipid particles (SNALPs) as a benchmark. DLinDMA is used for siRNA delivery .
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3
3 Cited Publications
Art. -Nr.: HY-130751
CAS. Nr.: 127512-29-2
Reinheit:  ≥98.0%
DODAP is a cationic lipid utilized as the lipid component in liposomes (pKa = 5.59 in TNS binding tests). DODAP is employed for encapsulating siRNA and delivering immunostimulated chemotherapeutic agents both in vitro and in vivo. DODAP holds great promise for research in vaccines and inflammation .
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2
2 Cited Publications
Art. -Nr.: HY-W590532
CAS. Nr.: 2566523-06-4
306-O12B is an ionizable cationic lipid used to prepare lipid nanoparticles (LNPs) for the delivery of mRNA .
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2
2 Cited Publications
Art. -Nr.: HY-145793
CAS. Nr.: 2328129-27-5
Reinheit:  ≥98.0%
FTT5 is an ionizable lipid that can be used to prepare lipid nanoparticles for efficient delivery of long-chain mRNA in vivo .
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2
2 Cited Publications
Art. -Nr.: HY-113266
CAS. Nr.: 40225-14-7
Reinheit:  ≥95.0%
Valerylcarnitine is an endogenous metabolite, belonging to the short-chain acylcarnitines. Valerylcarnitine acts as a metabolomic biomarker for ionizing radiation exposure in nonhuman primates. Valerylcarnitine can be used for the research of type 1 diabetes .
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1
1 Cited Publications
Art. -Nr.: HY-113485
CAS. Nr.: 8049-97-6
Reinheit:  ≥99.0%
Melanin is a unique pigment with myriad functions. It is multifunctional, providing defense against environmental stresses such as ultraviolet (UV) light, oxidizing agents and ionizing radiation.
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1
1 Cited Publications
Art. -Nr.: HY-151507
CAS. Nr.: 2322290-93-5
Reinheit:  ≥98.0%
306Oi10 is a branched ionizable lipid that can be used to construct lipid nanoparticles (LNPs) for delivering messenger RNA. The surface ionization of lipid nanoparticles is related to the effectiveness of mRNA delivery. The tail of 306Oi10 has a one-carbon branch, which provides it with stronger surface ionization compared to lipids with linear tails, thereby enhancing its mRNA delivery efficacy. 306Oi10 can be used in research related to mRNA delivery .
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1
1 Cited Publications
Art. -Nr.: HY-153373
CAS. Nr.: 2768211-13-6
4A3-Cit is an ionizable lipid used for the generation of lipid nanoparticles (LNPs).
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1
1 Cited Publications
Art. -Nr.: HY-156630
CAS. Nr.: 2055939-68-7
Reinheit:  ≥98.0%
Ionizable lipid-1 (compound II-10) is an ionizable lipid (pKa=6.16) that can be used to prepare lipid nanoparticles (LNP) with bilayer structure .
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1
1 Cited Publications
Art. -Nr.: HY-150115
CAS. Nr.: 2430034-02-7
Reinheit:  ≥95.0%
Lipid 10 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).
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1
1 Cited Publications
Art. -Nr.: HY-112772A
CAS. Nr.: 917572-74-8
Reinheit:  ≥98.0%
98N12-5 is a novel multi-tail ionizable lipids that has been used for efficient in vivo siRNA-delivery to the liver.
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1
1 Cited Publications
Art. -Nr.: HY-139298
CAS. Nr.: 1351586-50-9
Reinheit:  ≥98.0%
Synonyms: Di((Z)-Non-2-en-1-yl) 9-((4-(dimethylamino)butanoyl)oxy)heptadecanedioate
L319 is an ionizable cationic lipidoid and can be used for synthetic liposomes, from the patent WO-2011153493-A2, compound 1 .
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1
1 Cited Publications
Art. -Nr.: HY-15620
CAS. Nr.: 188247-01-0
Reinheit:  98.90%
Methylproamine is a DNA-binding radioprotector, acts by repair of transient radiation-induced oxidative species on DNA. Methylproamine also protects against ionizing radiation by preventing DNA double-strand breaks .
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