42 Results for "

laxative

" in MedChemExpress (MCE) Product Catalog:
Products (42)

42 Results for "laxative" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-107799
CAS No.: 8001-79-4
Castor oil is a natural triglyceride and a solvent. Castor oil has a laxative effect and induces labor in pregnant females. Castor oil can be used as a solvent, co-solvent, stabilizing agent and polyol for the formation of polymer-nanoparticle composites .
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3
3 Cited Publications
Cat. No.: HY-N0886
CAS No.: 28371-16-6
Synonyms: Isobarbaloin
Aloin B (Isobarbaloin) is an orally active SARS-CoV-2 papain-like protease (PLpro) inhibitor with an IC50 of 16.08 μM (hydrolytic activity) and 17.51 μM (deubiquitinase activity). Aloin B is metabolized by rat intestinal flora into aloe-emodin-9-anthrone to exert laxative effects. Aloin B inhibits TPA (HY-18739)-induced ear edema, putrescine elevation, and tumor promotion in mouse skin. Aloin B can be used in research related to anti-inflammation, tumor promotion inhibition, coronavirus disease 2019 (COVID-19) and constipation .
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2
2 Cited Publications
Cat. No.: HY-B0557
CAS No.: 603-50-9
Bisacodyl is a stimulant laxative agent that works directly on the colon to produce a bowel movement. Bisacodyl increases the secretion of PGE2 by direct activation of colon macrophages. PGE2 acts as a paracrine factor and decreases the expression of AQP3 in the colon, which inhibits water transfer from the luminal to the vascular side and leads to a laxative effect .
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1
1 Cited Publications
Cat. No.: HY-101714
CAS No.: 115-33-3
Purity:  98.41%
Target:  

Autophagy

Research Areas:  

Cancer

Oxyphenisatin acetate, the pro-agent of oxyphenisatin, is used to be a laxative.
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1
1 Cited Publications
Cat. No.: HY-B0544
CAS No.: 10040-45-6
Synonyms: Sodium Picosulphate
Sodium Picosulfate (Sodium Picosulphate) is a contact irritant laxative with oral activity. Sodium Picosulfate inhibits the absorption of water and electrolytes, increasing their production. Sodium Picosulfate can be used in colonoscopy applications .
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1
1 Cited Publications
Cat. No.: HY-Y0332C
CAS No.: 13472-35-0
Synonyms: Sodium phosphate dihydrate,≥99.0%
Sodium dihydrogen phosphate dihydrate,≥99.0% (Sodium phosphate dihydrate,≥99.0%) is used as a buffer capacity reagent in molecular biology, biochemistry, and chromatography. Sodium dihydrogen phosphate dihydrate,≥99.0% is also used as a laxative and pH buffer when combined with other sodium phosphates and also used as fuel and detergent additives .
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1
1 Cited Publications
Cat. No.: HY-107793
CAS No.: 1307301-38-7
Purity:  ≥98.0%
Target:  

Drug Derivative

Research Areas:  

Metabolic Disease

Picosulfate sodium salt hydrate is the hydrate of Sodium Picosulfate (HY-B0544). Picosulfate sodium salt hydrate is an orally active contact irritant laxative. Picosulfate sodium salt hydrate inhibits the absorption of water and electrolytes, increasing their production. Picosulfate sodium salt hydrate can be used in colonoscopy applications .
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Cat. No.: HY-N6070
CAS No.: 141-22-0
Ricinoleic acid (purity≥85%), a hydroxy fatty acid, is an attractive feedstock for the production of high-performance lubricants, cosmetics, polymers, surfactants, and coatings. Ricinoleic acid is the main active ingredient of Castor oil (HY-107799). Ricinoleic acid is the agonist for prostaglandin EP3 receptor (EP3 receptor) (EC50 in MEG-01 is 0.5 μM), that causes laxative effects and uterine contraction. Ricinoleic acid exhibits antianxiety-like, anti-inflammatory and pro-inflammatory properties .
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Cat. No.: HY-Y0308
CAS No.: 7558-79-4
Disodium phosphate is commonly used as a food additive, buffer and laboratory reagent. Disodium phosphate has unique chemical properties that make it an important ingredient in the manufacture of fertilizers, detergents and water treatment products. Additionally, it is used in various medical applications such as osmotic laxatives and electrolyte replacement solutions.
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Cat. No.: HY-B2102
CAS No.: 125-13-3
Synonyms: Oxyphenisatin
Target:  

Drug Derivative

Research Areas:  

Cancer

Oxyphenisatine (Oxyphenisatin) is a laxative. Oxyphenisatin acetate is the pro-agent of oxyphenisatin with anticancer activity.
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Cat. No.: HY-W105835
CAS No.: 3344-18-1
Synonyms: Trimagnesium dicitrate
Research Areas:  

Neurological Disease

Magnesium citrate (Trimagnesium dicitrate) is an orally active magnesium-containing compound that can cross the blood-brain barrier (BBB). Magnesium citrate can be used as an intestinal cleanser and is studied for its application in laxatives. Magnesium citrate can also increase the pain threshold and is studied for pain-relief purposes .
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Cat. No.: HY-N6070A
CAS No.: 141-22-0
Ricinoleic acid (purity≥99%), a hydroxy fatty acid, is an attractive feedstock for the production of high-performance lubricants, cosmetics, polymers, surfactants, and coatings. Ricinoleic acid is the main active ingredient of Castor oil (HY-107799). Ricinoleic acid is the agonist for prostaglandin EP3 receptor (EP3 receptor) (EC50 in MEG-01 is 0.5 μM), that causes laxative effects and uterine contraction. Ricinoleic acid exhibits antianxiety-like, anti-inflammatory and pro-inflammatory properties .
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Cat. No.: HY-P3499
CAS No.: 1092457-65-2
Target:  

Guanylate Cyclase

Research Areas:  

Inflammation/Immunology

Dolcanatide is an orally active GC-C (guanylate cyclase-C) agonist. Dolcanatide shows laxative, anti-nociceptive and anti-inflammatory activity. Dolcanatide can be used in inflammatory bowel disease research .
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Cat. No.: HY-N12326
CAS No.: 1350028-90-8
Multiflorin A is an active ingredient derived from Pruni semen. Multiflorin A has laxative activity. Multiflorin A inhibits intestinal glucose absorption and promotes bacterial metabolism .
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Cat. No.: HY-N1503
CAS No.: 52613-28-2
Synonyms: 6α-Hydroxygeniposide; Deacetylasperulosidic acid methyl ester
Methyl deacetylasperulosidate (6α-Hydroxygeniposide; Deacetylasperulosidic acid methyl ester) is an iridoid compound that acts as a laxative agent with blood glucose-lowering activity. It induces a laxative effect in mice and lowers blood glucose levels in normal mice .
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Cat. No.: HY-B2134
CAS No.: 8024-48-4
Casanthranol is a concentrated mixture of anthranol glycosides from cascara sagrada (dried bark of Rhamnus p.). Casanthranol can be used as a laxative in constipation and various medical conditions, stimulant laxative. Casanthranol encourages bowel movements by acting on the intestinal wall to increase muscle contractions. Casanthranol is protective in a PFF-induced toxicity model (EC50 = 34.2 μM) of N2a cells .
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Cat. No.: HY-131637
CAS No.: 603-41-8
Purity:  ≥99.0%
Target:  

Drug Metabolite

Research Areas:  

Metabolic Disease

Desacetyl bisacodyl is the active metabolite of the laxative bisacodyl. Desacetyl bisacodyl induces epithelial Cl(-) secretion in rat colon and rectum. Desacetyl bisacodyl evokes several effects at the colon or rectum, including increased mucus and chloride secretion .
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Cat. No.: HY-W094517
CAS No.: 7782-85-6
Sodium phosphate dibasic heptahydrate is an orally active and osmotic laxative, often used as a component of over-the-counter gastrointestinal lavage drugs. Sodium phosphate dibasic heptahydrate draws water into the intestinal lumen, maintains electrical neutrality by retaining cations in the intestinal lumen, and thereby alters fecal volume, consistency and phosphate levels. Sodium phosphate dibasic heptahydrate can be used to generate self-assembled calcium phosphate tubular scaffolds, which support the adhesion, survival and elongation of mesenchymal stem cells. Sodium phosphate dibasic heptahydrate can be applied to research on factitious disorders and related fields .
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Cat. No.: HY-N12281
CAS No.: 517-43-1
Sennoside is an orally active apoptosis inducer and stimulant laxative, found in Senna (Cassia angustifolia). Sennoside induces overexpression of wild-type p53 and p21/WAF as part of pathways mediating colonic epithelial cell apoptosis. Sennoside stimulates colonic peristalsis, reverses net water, sodium, chloride absorption to secretion and enhances potassium and calcium secretion. Sennoside increases paracellular permeability to small molecules, accelerates colon transit and softens fecal pellets. Sennoside can be used for the research of constipation, melanosis coli, and colorectal cancer .
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Cat. No.: HY-121068
CAS No.: 17692-24-9
Research Areas:  

Infection

Bisoxatin is a laxative drug used for constipation. Bisoxatin binds substantially at the S-protein-ACE2 interface. Bisoxatin has the potential for inhibiting SARS-CoV-2 entry into the host research .
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