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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
310 Results for "
lipid conjugate
" in MedChemExpress (MCE) Product Catalog:
Products (310)
310 Results for "lipid conjugate" in MCE Product Catalog:
8
8 Publications Verification
Synonyms: CMX001; HDP-CDV
Target:
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Brincidofovir (CMX001), the lipid-conjugated prodrug of Cidofovir (HY-17438), is an orally available, long-acting antiviral. Brincidofovir shows activity against a broad spectrum of DNA viruses including cytomegalovirus (CMV), adenovirus (ADV), varicella zoster virus, herpes simplex virus, polyomaviruses, papillomaviruses, poxviruses, and mixed double-stranded DNA virus infections. Brincidofovir, an oral antiviral in late stage development, has proven effective against orthopoxviruses in vitro and in vivo .
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2 Cited Publications
Synonyms: T-α-MCA sodium
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1 Cited Publications
Synonyms: DSPE-mPEG2000 sodium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] sodium
18:0 mPEG2000 PE (DSPE-mPEG2000) sodium is a conjugate of phospholipid and polyethylene glycol, and it can serve as an important PEG lipid component in lipid nanoparticles (LNPs). 18:0 mPEG2000 PE sodium can be used in the research of gene transfection, drug carriers and drug delivery .
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Elacytarabine (CP 4055) is a lipid-conjugated derivative of the nucleoside analog cytarabine. Elacytarabine (CP 4055) is an antineoplastic agent with cytotoxicity in solid tumors.
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1 Cited Publications
Cat. No.: HY-168374
CAS No.: 1829524-73-3
Research Areas:
DSPE-PEG 2000-Mannose is a mannose-containing lipid. DSPE-PEG 2000-Mannose is used to prepare mannose-conjugated Liposome (Man-lipo) for siRNA delivery. Mannose-modified liposomes encapsulating IDO siRNA (Man-lipo-siIDO) preferentially knock down IDO expression in the draining lymph nodes and spleens of melanoma-bearing mice. Man-lipo-siIDO delays the onset time of melanoma and reduces tumor volume .
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1 Cited Publications
Synonyms: Trichosanic acid
Category:
Punica granatum L. Ketones, Aldehydes, Acids Metabolic Disease Punicaceae Plants Disease Research Fields
Target:
1
1 Cited Publications
Cat. No.: HY-W591424
CAS No.: 92451-01-9
Synonyms: mPEG2000-SC; mPEG2000-Succinimidyl ester
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It is recommended to prepare a solution with concentration ≥2 mg/mL. Vortex thoroughly for more than 10 minutes. Due to the adsorption characteristics of LPS, silanized container or low adsorption centrifuge tubes should be used for aliquoting and storage, and mix thoroughly before use.
Synonyms: 14:0 PEG2000 PE ammonium; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] ammonium
DMPE-PEG2000 ammonium (14:0 PEG2000 PE ammonium) is a PEG-phospholipid conjugate to prepare nanostructured lipid carrier .
Cat. No.: HY-W440915
CAS No.: 1000788-53-3
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DSPE-PEG2000-FITC is a PEG lipid conjugated with fluorescein. FITC is a green dye with a peak absorption at 494 nm and a maximum emission at 520 nm, which is used for staining biological samples or nanoparticles. DSPE-PEG2000-FITC spontaneously forms lipid bilayers or micelles in water and can be used to prepare liposomes for delivering substances such as mRNA vaccines .
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Bilirubin Conjugate disodium is a peroxyl radical scavenger and chain-breaking antioxidant that inhibits lipid peroxidation by undergoing addition reactions with pyrrole moieties and accelerates copper ion-catalyzed decomposition of lipid hydroperoxides. Bilirubin Conjugate disodium is used in oxidative stress-related research .
Cat. No.: HY-140735
Purity: ≥95.0%
DSPE-PEG5000-Amine (DSPE-PEG5000-ammonium) is an amino-functionalized PEGylated lipid. DSPE-PEG5000-Amine can be conjugated with chlorin e6 (Ce6) via EDC/NHS coupling. It can also be conjugated with FITC to prepare DSPE-PEG-FITC. DSPE-PEG5000-Amine is applicable to research related to PEGylated lipid functionalization and bioconjugation .
Cat. No.: HY-160269
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DSPE-PEG2000-Fluor 488 is a PEG-dye-lipid conjugate consisting of a DSPE phospholipid and a Fluor 488 dye. DSPE is a phospholipid that spontaneously forms micelles in a water medium, and Fluor 488 is a cyanine dye that is widely used in fluorescence microscopy. Fluor 488 has excitation and emission maxima at 499 nm and 520 nm. Polyethylene glycol lipids are commonly used for the stabilization of lipid nanoparticles .
Cat. No.: HY-155907
CAS No.: 474922-26-4
Synonyms: DSPE-PEG5000-NH2 ammonium
DSPE-PEG5000-Amine ammonium (DSPE-PEG5000-NH2 ammonium) is an amino-functionalized PEGylated lipid. DSPE-PEG5000-Amine ammonium can be conjugated with chlorin e6 (Ce6) via EDC/NHS coupling. It can also be conjugated with FITC to prepare DSPE-PEG-FITC. DSPE-PEG5000-Amine ammonium is applicable to research related to PEGylated lipid functionalization and bioconjugation .
Cat. No.: HY-160578
CAS No.: 1257309-90-2
Synonyms: N-Cholesteryl succinyl glucosamine
Glucosamine Cholesterol (N-Cholesteryl succinyl glucosamine) is a glucosamine-based lipid conjugate, and can be used in the formation of lipid nanoparticles (LNPs) .
Cat. No.: HY-N15976
CAS No.: 3056014-09-3
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DMG-pSar25 Maleimide is a lipid conjugated to DMG, Maleimide and pSar25 polymer. DMG-pSar25 Maleimide can be used to prepare lipid nanoparticles for drug delivery.
Cat. No.: HY-144013A
CAS No.: 474922-77-5
Synonyms: DSPE-mPEG350 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-350] ammonium
18:0 mPEG350 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
