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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
174 Results for "
modifier
" in MedChemExpress (MCE) Product Catalog:
Products (174)
174 Results for "modifier" in MCE Product Catalog:
60
Target:
Research Areas:
Imiquimod (R 837), an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod exhibits antiviral and antitumor effects in vivo. Imiquimod can be used for the research of external genital, perianal warts, cancer and COVID-19 .
60
Target:
Research Areas:
Infection Neurological Disease Inflammation/Immunology Cancer
Imiquimod hydrochloride (R 837 hydrochloride), an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod hydrochloride exhibits antiviral and antitumor effects in vivo. Imiquimod hydrochloride can be used for the research of external genital, perianal warts, cancer and COVID-19 .
60
60 Publications Verification
Cat. No.: HY-B0180B
CAS No.: 896106-16-4
Target:
Research Areas:
Infection Neurological Disease Inflammation/Immunology Cancer
Imiquimod maleate (R 837 maleate), an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod maleate exhibits antiviral and antitumor effects in vivo. Imiquimod maleate can be used for the research of external genital, perianal warts, cancer and COVID-19 .
9
9 Cited Publications
Synonyms: RG7916; RO7034067
Target:
Research Areas:
Risdiplam (RG7916) is an orally administered, centrally and peripherally distributed SMN2 pre-mRNA splicing modifier that increases survival motor neuron (SMN) protein levels .
5
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Research Areas:
RG7800 is a SMN2 splicing modifier. RG7800 has the potential for spinal muscular atrophy treatment.
5
Research Areas:
Aurintricarboxylic acid is a nanomolar-potency, allosteric antagonist with selectivity towards αβ-methylene-ATP-sensitive P2X1Rs and P2X3Rs, with IC50s of 8.6 nM and 72.9 nM for rP2X1R and rP2X3R, respectively . Aurintricarboxylic acid is a potent anti-influenza agent by directly inhibiting the neuraminidase . Aurintricarboxylic acid is an inhibitor of topoisomerase II and apoptosis . Aurintricarboxylic acid is a selective inhibitor of the TWEAK-Fn14 signaling pathway . Aurintricarboxylic acid also acts as a cystathionine-lyase (CSE) inhibitor with an IC50 of 0.6 μM . Aurintricarboxylic acid is a modifier of miRNAs that regulate miRNA function, with an IC50 of 0.47 µM .
4
4 Cited Publications
Cat. No.: HY-W011950
CAS No.: 52417-22-8
Target:
Research Areas:
Acridin-9-amine (9-Aminoacridine) hydrochloride hydrate is a mutagen and DNA modifier. Acridin-9-amine hydrochloride hydrate induces mutagenic lesions during DNA replication .
3
3 Cited Publications
Synonyms: GAP-134 Hydrochloride; ZP 1609 Hydrochloride
Target:
Research Areas:
Danegaptide Hydrochloride (GAP-134 Hydrochloride) is a potent, selective and orally active gap-junction modifier with an antiarrhythmic effect .
2
2 Cited Publications
Cat. No.: HY-18593
CAS No.: 104723-60-6
Synonyms: 6-O-alpha-D-Maltosyl-beta-cyclodextrin
2
2 Cited Publications
Cat. No.: HY-P80351
Synonyms: DAP1 antibody;
GAP modifying protein 1 antibody;
GMP 1 antibody;
OFC10 antibody;
PIC 1 antibody;
PIC1 antibody;
SENP2 antibody;
Sentrin 1 antibody;
Sentrin antibody;
Small ubiquitin related modifier 1 antibody;
Small ubiquitin-like modifier 1 antibody;
Small ubiquitin-related modifier 1 antibody;
SMT3 antibody;
SMT3 homolog 3 antibody;
SMT3 suppressor of mif two 3 homolog 1 antibody;
SMT3, yeast, homolog 3 antibody;
Smt3C antibody;
SMT3H3 antibody;
SUMO-1 antibody;
SUMO1 antibody;
SUMO1_HUMAN antibody;
Ubiquitin homology domain protein PIC1 antibody;
Ubiquitin Like 1 antibody;
Ubiquitin like protein SMT3C antibody;
Ubiquitin like protein UBL1 antibody;
Ubiquitin-homology domain protein PIC1 antibody;
Ubiquitin-like protein SMT3C antibody;
Ubiquitin-like protein UBL1 antibody;
UBL 1 antibody;
UBL1 antibody
2
2 Cited Publications
Cat. No.: HY-P74485
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Ubiquitin-like modifier-activating enzyme 1; Protein A1S9; UBA1; A1S9T; UBE1
Species:
Source:
1
Target:
Efaproxiral (RSR13) is a haemoglobin (Hb) synthetic allosteric modifier. Efaproxiral decreases Hb-oxygen (O2) binding affinity and enhances oxygenation of hypoxic tumours during radiation therapy .
1
Target:
Efaproxiral (RSR13) sodium is a haemoglobin (Hb) synthetic allosteric modifier. Efaproxiral sodium decreases Hb-oxygen (O2) binding affinity and enhances oxygenation of hypoxic tumours during radiation therapy .
1
1 Cited Publications
Target:
Research Areas:
MS049, a chemical probe, is a potent, selective, and cell-active dual inhibitor of PRMT4 and PRMT6 with IC50s of 34 nM and 43 nM, respectively. MS049 reduces levels of Med12me2a and H3R2me2a in HEK293 cells. MS049 is not toxic and does not affect the growth of HEK293 cells .
1
1 Cited Publications
Target:
Research Areas:
GBT1118 is a potent and orally active allosteric modifier of hemoglobin oxygen affinity. GBT1118 increases tolerance to severe hypoxia .
1
1 Cited Publications
Synonyms: PABA potassium; p-Aminobenzoic acid potassium
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Research Areas:
4-Aminobenzoic acid (PABA) potassium is a modifier of catecholamine oxidation reactions. 4-Aminobenzoic acid potassium is promising for research of Parkinson's disease and hypertension .
1
1 Cited Publications
Cat. No.: HY-109101S
Purity: 98.88%
1
1
1 Cited Publications
Target:
Research Areas:
SENP1-IN-1 is a specific deSUMOylation protease 1 (SENP1) inhibitor extracted from patent CN110627860, Compound 29. SENP1-IN-1 is developed for tumor radiosensitivity enhancement .
1
1 Cited Publications
Cat. No.: HY-15929
CAS No.: 14348-40-4
Synonyms: 2,4,6-Tribromo-3-hydroxybenzoic acid
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
