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125

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2

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1

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17

Biochemical Assay Reagents

4

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6

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15

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10

Isotope-Labeled Compounds

22

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3

Click Chemistry

32

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0180
    Imiquimod
    Maximum Cited Publications
    58 Publications Verification

    R 837

    		 Toll-like Receptor (TLR) Autophagy SARS-CoV HSV Infection Inflammation/Immunology Cancer
    Imiquimod (R 837), an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod exhibits antiviral and antitumor effects in vivo. Imiquimod can be used for the research of external genital, perianal warts, cancer and COVID-19 .
    Imiquimod
  • HY-109101
    Risdiplam
    5+ Cited Publications

    RG7916; RO7034067

    		 DNA/RNA Synthesis Neurological Disease
    Risdiplam (RG7916) is an orally administered, centrally and peripherally distributed SMN2 pre-mRNA splicing modifier that increases survival motor neuron (SMN) protein levels .
    Risdiplam
  • HY-B0180A
    Imiquimod hydrochloride
    Maximum Cited Publications
    58 Publications Verification

    R 837 hydrochloride

    		 Toll-like Receptor (TLR) Autophagy SARS-CoV HSV Infection Neurological Disease Inflammation/Immunology Cancer
    Imiquimod hydrochloride (R 837 hydrochloride), an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod hydrochloride exhibits antiviral and antitumor effects in vivo. Imiquimod hydrochloride can be used for the research of external genital, perianal warts, cancer and COVID-19 .
    Imiquimod hydrochloride
  • HY-W014069
    11-Mercaptoundecanoic acid

    11-Thioundecanoic acid; MUA; MUDA

    		 Biochemical Assay Reagents Others
    11-Mercaptoundecanoic acid (11-Thioundecanoic acid; MUA; MUDA) is a self-assembled monolayer membrane composed of long-chain alkane chains and carboxyl-containing thioalcohols and can be used as a metal surface modifier. 11-Mercaptoundecanoic acid is widely applied in the research of molecular probes, self-assembled membranes, nanomaterials, and biological materials, etc .
    11-Mercaptoundecanoic acid
  • HY-112624C
    Dextran (MW 40000)

    		Biochemical Assay Reagents Endogenous Metabolite Others
    Dextran (MW 40000) is a complex carbohydrate polymer consisting of glucose molecules linked by glycosidic bonds. Dextran has excellent solubility in water, making it useful as a viscosity modifier or stabilizer in foods, paints and adhesives. In the biomedical field, dextran is often used as a plasma expander because of its ability to increase blood volume when administered intravenously. It can also be modified to create dextran-based drug delivery systems, such as targeted nanoparticles.
    Dextran (MW 40000)
  • HY-W015114
    L-2-Hydroxyglutaric acid disodium

    (S)-2-Hydroxyglutaric acid disodium

    		 Histone Demethylase Mitochondrial Metabolism Endogenous Metabolite Cancer
    L-2-Hydroxyglutaric acid disodium is an epigenetic modifier and putative oncometabolite in renal cancer. L-2-Hydroxyglutaric acid disodium can inhibit histone demethylases and hence promote histone methylation . L-2-Hydroxyglutaric acid inhibits mitochondrial creatine kinase (Mi-CK) activity with Km and Ki of 2.52 mM and 11.13 mM, respectively .
    L-2-Hydroxyglutaric acid disodium
  • HY-10913A
    Danegaptide Hydrochloride
    1 Publications Verification

    GAP-134 Hydrochloride; ZP 1609 Hydrochloride

    		 Gap Junction Protein Cardiovascular Disease
    Danegaptide Hydrochloride (GAP-134 Hydrochloride) is a potent, selective and orally active gap-junction modifier with an antiarrhythmic effect .
    Danegaptide Hydrochloride
  • HY-13619
    Efaproxiral
    1 Publications Verification

    RSR13

    		 Hemoglobin Infection Cancer
    Efaproxiral (RSR13) is a haemoglobin (Hb) synthetic allosteric modifier. Efaproxiral decreases Hb-oxygen (O2) binding affinity and enhances oxygenation of hypoxic tumours during radiation therapy .
    Efaproxiral
  • HY-W105426
    3-(Trimethoxysilyl)propyl methacrylate

    [3-(Methacryloyloxy)propyl]trimethoxysilane

    		 Biochemical Assay Reagents Others
    3-(Trimethoxysilyl)propyl methacrylate is a reactive monomer and silane coupling agent with C=C and O-C=O functional groups, acting as a surface modifier and anti-agglomeration agent. 3-(Trimethoxysilyl)propyl methacrylate can be used to prepare nanoparticles .
    3-(Trimethoxysilyl)propyl methacrylate
  • HY-139662
    HB007

    		E1/E2/E3 Enzyme Cancer
    HB007 is a small ubiquitin-related modifier 1 (SUMO1) degrader. HB007 induces ubiquitination and degradation of SUMO1, resulting in reduced tumor growth in vivo. HB007 can be used for the research of brain, breast, colon, and lung cancers .
    HB007
  • HY-101792
    RG7800
    5 Publications Verification

    RO6885247

    		 DNA/RNA Synthesis Others
    RG7800 is a SMN2 splicing modifier. RG7800 has the potential for spinal muscular atrophy treatment.
    RG7800
  • HY-Y0873O
    PEG35000

    Polyethylene glycol 35000

    		 Environmental Pollutants Biochemical Assay Reagents Others
    PEG35000 is a polyethylene glycol with a molecular weight of 35,000 that can be used as a carrier material and modifier in drug delivery systems .
    PEG35000
  • HY-105336
    3-Deazauridine

    NSC 126849

    		 DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Cancer
    3-Deazauridine (NSC 126849) is a uridine analogue. 3-Deazauridine competitively inhibits cytidine triphosphate synthase to inhibit the biosynthesis of cytidine-5'-triphosphate. 3-Deazauridine acts synergistically with several antineoplastic agents, acting as a biological response modifier .
    3-Deazauridine
  • HY-W145516
    Guar gum

    		Environmental Pollutants Biochemical Assay Reagents Metabolic Disease
    Guar gum is an orally active nonionic galactomannan polysaccharide. It is present in the endosperm of Cyamopsis tetragonolobus seeds. Guar gum reduces cholesterol levels, regulates body weight, and acts as a thickener and viscosity modifier by forming hydrogen-bonded aqueous solutions. It serves as a rate-controlling excipient in compound delivery systems, and finds applications in the food, tissue engineering, nanosensing and industrial fields .
    Guar gum
  • HY-113039
    L-2-Hydroxyglutaric acid

    (S)-2-Hydroxyglutaric acid

    		 Histone Demethylase Mitochondrial Metabolism Endogenous Metabolite Cancer
    L-2-Hydroxyglutaric acid is an epigenetic modifier and putative oncometabolite in renal cancer. L-2-Hydroxyglutaric acid can inhibit histone demethylases and hence promote histone methylation . L-2-Hydroxyglutaric acid inhibits mitochondrial creatine kinase (Mi-CK) activity with Km and Ki of 2.52 mM and 11.13 mM, respectively .
    L-2-Hydroxyglutaric acid
  • HY-W129513
    Sorbitan monopalmitate

    		Biochemical Assay Reagents Others
    Sorbitan monopalmitate is a food-grade, non-ionic emulsifier that exhibits oral activity. Sorbitan monopalmitate functions as a crystallization modifier, promoting the aggregation of spherical mango butter crystals, introducing lattice defects, and regulating the crystallization rate of mango butter. Sorbitan monopalmitate serves as a component of precursor vesicle gels, enabling the controlled and sustained release of drugs and facilitating the preparation of stable transdermal delivery formulations .
    Sorbitan monopalmitate
  • HY-18593
    Mal-β-CD
    2 Publications Verification

    6-O-alpha-D-Maltosyl-beta-cyclodextrin

    		 Biochemical Assay Reagents Others
    Mal-β-CD is a cellular cholesterol modifier which can form soluble inclusion complex with cholesterol.
    Mal-β-CD
  • HY-13619A
    Efaproxiral sodium
    1 Publications Verification

    RSR13 sodium

    		 Hemoglobin Infection Cancer
    Efaproxiral (RSR13) sodium is a haemoglobin (Hb) synthetic allosteric modifier. Efaproxiral sodium decreases Hb-oxygen (O2) binding affinity and enhances oxygenation of hypoxic tumours during radiation therapy .
    Efaproxiral sodium
  • HY-B0180B
    Imiquimod maleate
    Maximum Cited Publications
    58 Publications Verification

    		 Toll-like Receptor (TLR) Autophagy SARS-CoV HSV Infection Neurological Disease Inflammation/Immunology Cancer
    Imiquimod maleate (R 837 maleate), an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod maleate exhibits antiviral and antitumor effects in vivo. Imiquimod maleate can be used for the research of external genital, perianal warts, cancer and COVID-19 .
    Imiquimod maleate
  • HY-100360
    MS049
    1 Publications Verification

    		 Histone Methyltransferase Cancer
    MS049, a chemical probe, is a potent, selective, and cell-active dual inhibitor of PRMT4 and PRMT6 with IC50s of 34 nM and 43 nM, respectively. MS049 reduces levels of Med12me2a and H3R2me2a in HEK293 cells. MS049 is not toxic and does not affect the growth of HEK293 cells .
    MS049
  • HY-153182
    GBT1118

    		Drug Derivative Cardiovascular Disease
    GBT1118 is a potent and orally active allosteric modifier of hemoglobin oxygen affinity. GBT1118 increases tolerance to severe hypoxia .
    GBT1118
  • HY-B1008A
    4-Aminobenzoic acid potassium
    1 Publications Verification

    PABA potassium; p-Aminobenzoic acid potassium

    		 Endogenous Metabolite Cardiovascular Disease Neurological Disease
    4-Aminobenzoic acid (PABA) potassium is a modifier of catecholamine oxidation reactions. 4-Aminobenzoic acid potassium is promising for research of Parkinson's disease and hypertension .
    4-Aminobenzoic acid potassium
  • HY-W250112
    Lignin alkali

    		Environmental Pollutants Biochemical Assay Reagents Others
    Lignin alkali acts as a decomposer, depolymerizer and structural modifier. Lignin alkali is recovered from lignocellulosic biomass via alkaline pretreatment. Lignin alkali consists of p-hydroxyphenyl, guaiacyl and syringyl propanoid units. Lignin alkali can be custom-converted into high-value-added chemicals and materials. Lignin alkali exhibits significant application potential in the fields of biomass refining and high-value utilization .
    Lignin alkali
  • HY-W040294
    Methyl α-D-glucoside

    Methyl α-D-glucopyranoside

    		 Biochemical Assay Reagents Others
    Methyl α-D-glucoside (Methyl α-D-glucopyranoside) can be used for protein glycosylation modification. Methyl α-D-glucoside is a kind of biological materials or organic compounds that are widely used in life science research .
    Methyl α-D-glucoside
  • HY-E70372
    SUMO Protease

    		Biochemical Assay Reagents Others
    SUMO Protease is highly specific for proteins containing small ubiquitin-like modifier (SUMO) tags. SUMO Protease can be used to regulates the proteins splicing, controlls protein structure and function in vitro .
    SUMO Protease
  • HY-109101S
    Risdiplam-d4
    1 Publications Verification

    		 DNA/RNA Synthesis Neurological Disease
    Risdiplam-d4 is deuterium labeled Risdiplam. Risdiplam (RG7916) is an orally administered, centrally and peripherally distributed SMN2 pre-mRNA splicing modifier that increases survival motor neuron (SMN) protein levels .
    Risdiplam-d4
  • HY-W007791
    Chloropurine riboside

    6-Chloropurine riboside

    		 Nucleoside Antimetabolite/Analog Bacterial Infection
    Chloropurine (6-Chloropurine) riboside is an analog of Adenosine (HY-B0228). Chloropurine riboside acts as a chemical modifier for affinity labeling of RNase A. Chloropurine riboside exhibits antibacterial activity and can be used in studies related to citrus Huanglongbing (HLB) .
    Chloropurine riboside
  • HY-N7438
    Mogroside VI A

    		Others Others
    Mogroside VI A, an isomer of Mogroside VI isolated from Luo Han Guo, exerts sweetness property. Mogroside VI A can be used for sweetener and/or taste modifier research .
    Mogroside VI A
  • HY-10913
    Danegaptide

    GAP-134; ZP 1609

    		 Gap Junction Protein Cardiovascular Disease
    Danegaptide (GAP-134) is a potent, selective and orally active gap-junction modifier with an antiarrhythmic effect .
    Danegaptide
  • HY-N10346A
    Gluconapin

    3-Butenyl glucosinolate

    		 Lipase Bacterial Infection Cancer
    Gluconapin (3-Butenyl glucosinolate) is an orally active aliphatic glucosinolate and also a flavor modifier. Gluconapin inhibits the elevation of plasma triglyceride levels in mice. Gluconapin also exhibits certain antibacterial activity .
    Gluconapin
  • HY-B0180R
    Imiquimod (Standard)

    R 837 (Standard)

    		 Reference Standards Toll-like Receptor (TLR) Autophagy SARS-CoV HSV Infection Inflammation/Immunology Cancer
    Imiquimod (Standard) is the analytical standard of Imiquimod. This product is intended for research and analytical applications. Imiquimod (R 837), an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod exhibits antiviral and antitumor effects in vivo. Imiquimod can be used for the research of external genital, perianal warts, cancer and COVID-19 .
    Imiquimod (Standard)
  • HY-158118
    Lys(CO-C3-p-I-Ph)-OMe

    		DNA-PK Cancer
    Lys(CO-C3-p-I-Ph)-OMe is a pharmacokinetic modifier (PK modifier) that can improve the PK properties of PSMA ligand molecules (such as Ac-PSMA-trillium). Lys(CO-C3-p-I-Ph)-OMe can increase the residence time of Ac-PSMA-trillium in plasma by increasing its binding capacity to albumin. Lys(CO-C3-p-I-Ph)-OMe also reduces salivary gland absorption of Ac-PSMA-trillium, potentially extending its half-life. Ac-PSMA-trillium is a suitable PSMA-targeting compound that has different biological applications after modification with different radioactive isotopes. If labeled with 111In, it can be used as DOTA chelating agent and imaging agent. Or labeled with 225Ac as a Macropa chelator for targeted radionuclide therapy (TRT) in the study of metastatic castration-resistant prostate cancer (mCRPC) .
    Lys(CO-C3-p-I-Ph)-OMe
  • HY-159204
    3'-Amino-Modifier C7 CPG 1000

    		Biochemical Assay Reagents
    3'-Amino-Modifier C7 CPG 1000 is a kind of biochemical reagent.
    3'-Amino-Modifier C7 CPG 1000
  • HY-W129456
    Isaxonine

    		Biochemical Assay Reagents Neurological Disease
    Isaxonine acts as a modifier of the surface pH of the bilayer . Isaxonine accelerates the rate of peripheral nerve regeneration, stimulate axonal sprouting and promote motor and sensory function recovery . Isaxonine is a neurotrophic agent .
    Isaxonine
  • HY-W250721E
    Carbomer copolymer

    Carboxy polymethylene (copolymer)

    		 Biochemical Assay Reagents Others
    Carbomer copolymer can be used as an excipient, such as Bioadhesives, emulsifiers, release modifiers, suspending agents, tablet binders, viscosity enhancers, etc. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
    Carbomer copolymer
  • HY-E70420
    SpeB cysteine protease

    		Bacterial Inflammation/Immunology
    SpeB cysteine protease is a potent modifier of immunologically important host and bacterial proteins. SpeB cysteine protease degrades streptolysin O (SLO) in extracellular vesicles .
    SpeB cysteine protease
  • HY-158122
    Lys(CO-C3-p-I-Ph)-O-tBu

    		DNA-PK Cancer
    Lys(CO-C3-p-I-Ph)-O-tBu is a pharmacokinetic modifier (PK modifier) that can improve the pharmacokinetic properties of PSMA ligand molecules. Lys(CO-C3-p-I-Ph)-O-tBu can increase the residence time of PSMA ligand in plasma by increasing its binding capacity to albumin. Lys(CO-C3-p-I-Ph)-O-tBu also reduces salivary gland absorption, possibly extending the half-life of the active compound .
    Lys(CO-C3-p-I-Ph)-O-tBu
  • HY-128899
    MC-Val-Cit-PAB-Auristatin E

    		Drug-Linker Conjugates for ADC Cancer
    MC-Val-Cit-PAB-Auristatin E is a agent-linker conjugate for ADC with potent antitumor activity by using Auristatin E (a cytotoxic tubulin modifier), linked via the ADC linker MC-Val-Cit-PAB.
    MC-Val-Cit-PAB-Auristatin E
  • HY-W704600
    1,3-Distearoyl-2-oleoyl glycerol

    TG(18:0/18:1/18:0)

    		 Biochemical Assay Reagents Others
    1,3-Distearoyl-2-oleoyl glycerol (TG(18:0/18:1/18:0)) is a triglyceride that can be isolated from native fats such as such as kokum, shea butter and mango kernel fat. 1,3-Distearoyl-2-oleoyl glycerol is widely used in the chocolate industry as a cocoa butter modifier and an anti-blooming agent .
    1,3-Distearoyl-2-oleoyl glycerol
  • HY-111945
    Cys modifier 1

    		Fluorescent Dye Others
    Cys modifier 1 (compound 7) is a cysteine-selective protein modifier for protein bioconjugation. A fluorescent carbonylacrylic derivative bearing nitrobenzofurazan (λex=465nm and λem539 nm)[1].
    Cys modifier 1
  • HY-159656
    PNPLA3 modifier 1

    		PNPLA3 Others
    PNPLA3 modifier 1 (compound 10) is a Patatin-like phospholipase domain-containing protein 3 (pnpla3) modifier, with a geometric mean EC50 of 4.9 nM .
    PNPLA3 modifier 1
  • HY-W714969A
    BCN-CE-phosphoramidite

    		Phosphoramidites Others
    BCN-CE-phosphoramidite is an oligonucleotide modifier containing a BCN strained cyclooctyne structure. BCN-CE-phosphoramidite possesses bioorthogonal reactivity and bioconjugation capability .
    BCN-CE-phosphoramidite
  • HY-W011950
    Acridin-9-amine hydrochloride hydrate
    4 Publications Verification

    		 DNA/RNA Synthesis Others
    Acridin-9-amine (9-Aminoacridine) hydrochloride hydrate is a mutagen and DNA modifier. Acridin-9-amine hydrochloride hydrate induces mutagenic lesions during DNA replication .
    Acridin-9-amine hydrochloride hydrate
  • HY-145989
    Aminobenzenesulfonic auristatin E

    		Drug-Linker Conjugates for ADC Microtubule/Tubulin Cancer
    Aminobenzenesulfonic auristatin E is a agent-linker conjugate for ADC. Aminobenzenesulfonic auristatin E has potent antitumor activity by using Auristatin E (a cytotoxic tubulin modifier), linked via the ADC linker Aminobenzenesulfonic .
    Aminobenzenesulfonic auristatin E
  • HY-113811
    Diisopropyl xanthogen disulfide

    DIXDS; Diproxide

    		 Biochemical Assay Reagents Others
    Diisopropyl xanthogen disulfide (DIXDS) is a superaccelerator for natural rubber and latex, styrene-butadiene rubber and latex, nitrile butadiene rubber and recycled rubber. It can also be used as a neoprene rubber modifier and an insoluble sulfur stabilizer .
    Diisopropyl xanthogen disulfide
  • HY-109101R
    Risdiplam (Standard)

    RG7916 (Standard); RO7034067 (Standard)

    		 Reference Standards DNA/RNA Synthesis Neurological Disease
    Risdiplam (Standard) is the analytical standard of Risdiplam. This product is intended for research and analytical applications. Risdiplam (RG7916) is an orally administered, centrally and peripherally distributed SMN2 pre-mRNA splicing modifier that increases survival motor neuron (SMN) protein levels .
    Risdiplam (Standard)
  • HY-178458
    UBA5-IN-2

    		E1/E2/E3 Enzyme Metabolic Disease Cancer
    UBA5-IN-2 (Compound 50) is a potent ubiquitin-like modifier activating enzyme 5 (UBA5) inhibitor (IC50=0.063 μM). UBA5-IN-2 is promising for research of cancers and protein homeostasis-related diseases .
    UBA5-IN-2
  • HY-B0180S1
    Imiquimod-d9

    R 837-d9

    		 Isotope-Labeled Compounds Toll-like Receptor (TLR) Autophagy SARS-CoV HSV Infection Inflammation/Immunology Cancer
    Imiquimod-d9 is deuterium labeled Imiquimod. Imiquimod (R 837), an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod exhibits antiviral and antitumor effects in vivo. Imiquimod can be used for the research of external genital, perianal warts, cancer and COVID-19 .
    Imiquimod-d9
  • HY-B0180S
    Imiquimod-d6

    R 837-d6

    		 Toll-like Receptor (TLR) Autophagy SARS-CoV HSV Infection Inflammation/Immunology Cancer
    Imiquimod-d6 is the deuterium labeled Imiquimod. Imiquimod (R 837), an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod exhibits antiviral and antitumor effects in vivo. Imiquimod can be used for the research of external genital, perianal warts, cancer and COVID-19 .
    Imiquimod-d6
  • HY-100360A
    MS049 dihydrochloride

    		Histone Methyltransferase Cancer
    MS049 dihydrochloride is a potent, selective, and cell-active dual inhibitor of PRMT4 and PRMT6 with IC50s of 34 nM and 43 nM, respectively. MS049 dihydrochloride reduces levels of Med12me2a and H3R2me2a in HEK293 cells. MS049 dihydrochloride is not toxic and does not affect the growth of HEK293 cells .
    MS049 dihydrochloride

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