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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
21 Results for "
p73
" in MedChemExpress (MCE) Product Catalog:
Products (21)
21 Results for "p73" in MCE Product Catalog:
2
2 Cited Publications
Cat. No.: HY-19726
CAS No.: 803647-40-7
NSC59984 induces mutant p53 protein degradation via MDM2 and the ubiquitin-proteasome pathway . NSC59984 acts by targeting GOF-mutant p53 and stimulates p73 to restore the p53 pathway signaling .
Research Areas:
RETRA is a RIPK1/RIPK3/MLKL and p73 activator. RETRA mediates plasma membrane disruption, induces ROS accumulation, triggers early mitochondrial hyperpolarization, and synergistically drives necroptosis. RETRA inhibits cancer cells carrying mutant p53 via a p73-dependent salvage pathway. RETRA can be used in research related to cervical cancer and cancers with mutant p53 .
Cat. No.: HY-113843
CAS No.: 1035875-01-4
RETRA (hydrobromide) is a mutant p53-dependent activator of p73 that can inhibit cancer cells carrying mutant p53. RETRA (hydrobromide) increases the expression level of p73, induces transcriptional activation of several common to transcriptional targets p53 and p73, which leads to mutant p53- and p73-dependent inhibition of tumor growth, reduction of colony formation and induction of effector caspases .
Cat. No.: HY-P702989
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Tp73; Transcription Factor DNp73; Tumor Protein p73; Cellular Tumor Antigen P53; p73; DeltaN p73; P53-Like Transcription Factor; CILD47; P53-Related Protein; HDNp73
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P702990
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Tp73; Transcription Factor DNp73; Tumor Protein p73; Cellular Tumor Antigen P53; p73; DeltaN p73; P53-Like Transcription Factor; CILD47; P53-Related Protein; HDNp73
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P702991
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Tp73; Transcription Factor DNp73; Tumor Protein p73; Cellular Tumor Antigen P53; p73; DeltaN p73; P53-Like Transcription Factor; CILD47; P53-Related Protein; HDNp73
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P81495A
Synonyms: Tp73; p73; Tumor protein p73; p53-like transcription factor; p53-related protein
Cat. No.: HY-RS14924
Target:
Research Areas:
TP73 Human Pre-designed siRNA Set A contains three designed siRNAs for TP73 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS26467
Target:
Research Areas:
Tp73 Rat Pre-designed siRNA Set A contains three designed siRNAs for Tp73 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS00924
Target:
Research Areas:
ARHGAP24 Human Pre-designed siRNA Set A contains three designed siRNAs for ARHGAP24 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-115797
CAS No.: 2180931-49-9
LQFM030 is a novel small molecule MDM2 inhibitor. LQFM030 exhibits concentration dependent cytotoxicity in K562 cells (IC50 = 0.28 mM). LQFM030 induces cell apoptosis through G0/G1 phase cell cycle arrest and increased Caspase activity. LQFM030 downregulates the mRNA expression of MDM2, MDMX, p73, MYC, and NF-κB. LQFM030 is commonly used in research on cancers such as leukemia .
Cat. No.: HY-P86227
Synonyms: KET, P63, p73H, p73L, Tp73L, TP63, Tumor protein 63, p63, Chronic ulcerative stomatitis protein, Keratinocyte transcription factor KET, Transformation-related protein 63, Tumor protein p73-like, p40, p51, CUSP, p73L
Cat. No.: HY-P73734
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TP63; Chronic Ulcerative Stomatitis Protein; Prev. Tp73L; Tumor Protein P53-Competing Protein; Prev. TP53CP; Transformation-Related Protein 63; Prev. TP53L; Tumor Protein p73-Like; p73L; Tumor Protein 63; p73H; Amplified In Squamous Cell Carcinoma; P51; C
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P86745
Synonyms: P63_HUMAN; Tumor protein 63; TP63; Chronic ulcerative stomatitis protein(CUSP); Keratinocyte transcription factor KET; Transformation-related protein 63(TP63); Tumor protein p73-like(p73L); p40; p51; KET; P63; p73H; p73L; Tp73L; AIS; LMS; NBP; RHS; p40; p51; EEC3; OFC8; SHFM4; TP53L; p53CP; TP53CP; B(p51A); B(p51B); P51A; TAp63gamma; P51B; TAp63alpha; P51delta; TAp63delta; P51delNalpha; deltaNp63 alpha; P51delNbeta; deltaNp63 beta; P51delNgamma; deltaNp63gamma; p40-deltaNp63; p40-deltaNp63;
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
