LQFM030
LQFM030 is a novel small molecule MDM2 inhibitor. LQFM030 exhibits concentration dependent cytotoxicity in K562 cells (IC50 = 0.28 mM). LQFM030 induces cell apoptosis through G0/G1 phase cell cycle arrest and increased Caspase activity. LQFM030 downregulates the mRNA expression of MDM2, MDMX, p73, MYC, and NF-κB. LQFM030 is commonly used in research on cancers such as leukemia.
For research use only. We do not sell to patients.
- CAS No.: 2180931-49-9
- Formula: C16H19ClN4O
- Molecular Weight:318.80
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Biological Activity
Chemical Information
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CAS No. 2180931-49-9
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Molecular Weight 318.80
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Formula C16H19ClN4O
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SMILES
CC(N1CCN(CC2=CN(C3=CC=C(Cl)C=C3)N=C2)CC1)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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