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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
54 Results for "
pH-sensitive
" in MedChemExpress (MCE) Product Catalog:
Products (54)
54 Results for "pH-sensitive" in MCE Product Catalog:
5
5 Cited Publications
Cat. No.: HY-15940
CAS No.: 72088-94-9
Synonyms: 5(6)-FAM; 5-(and-6)-Carboxyfluorescein mixed isomers
3
3 Cited Publications
Synonyms: 2′,7′-Bis(2-carboxyethyl)-5(6)-carboxyfluorescein
3
2
1
1 Cited Publications
Cat. No.: HY-D1563
CAS No.: 312961-83-4
1
1 Cited Publications
CL4H6 is a pH-sensitive cationic lipid. CL4H6 is the main component of lipid nanoparticles (LNPs), which can be used to target and deliver siRNA, and induces a potent gene-silencing response .
Cat. No.: HY-P4108
CAS No.: 923954-79-4
Target:
Research Areas:
Cat. No.: HY-P99681
CAS No.: 1469876-18-3
Synonyms: IMMU 130; hMN-14-SN-38
Target:
Research Areas:
Labetuzumab govitecan (IMMU 130) is an Anti-CEACAM5/SN-38 antibody-drug conjugate (ADC). Labetuzumab govitecan consists of the antibody Labetuzumab, SN-38, and a pH-sensitive Linker. Labetuzumab govitecan can be used for research of cancers, such as colorectal cancer .
Cat. No.: HY-W040144
CAS No.: 76-60-8
Cat. No.: HY-D0077
CAS No.: 195136-58-4
Synonyms: Oregon green 488
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2',7'-Difluorofluorescein (Oregon green 488) is a fluorescein derivative and a pH-sensitive fluorescent probe (pKa ~4.7). Upon excitation at 488 nm, 2',7'-Difluorofluorescein exhibits pH-sensitive fluorescence intensity through the formation of dianions, while its pH sensitivity decreases under excitation at 450 nm, allowing its use in ratiometric pH analysis. 2',7'-Difluorofluorescein can be used for the quantitative analysis of pH values in the range of 2-7 in submicron aerosol particles. 2',7'-Difluorofluorescein undergoes buffer-mediated and buffer-free excited-state proton transfer between different protonated forms, and its cationic form undergoes rapid excited-state deprotonation. 2',7'-Difluorofluorescein is resistant to photodegradation, maintains stable absorption and fluorescence properties within the physiological pH range, and serves as a fluorescent protein label, a component of Ca 2+ indicators, a fluorescent imaging agent, and an anisotropy probe .
Cat. No.: HY-D0075
CAS No.: 61255-63-8
Synonyms: NapHthafluorescein
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Naphthofluorescein inhibits the interaction between HIF-1 and Mint3.
Naphthofluorescein suppresses Mint3-dependent HIF-1 activity and glycolysis in cancer cells and macrophages without cytotoxicity in vitro and adverse effect in vivo . Naphthofluorescein is also a fluorescent pH-sensitive probe that can be used for functional Cerenkov imaging .
Cat. No.: HY-W133967
CAS No.: 9005-35-0
Research Areas:
Calcium alginate is a biopolymer that can be used for developing oral agent-delivery systems . Calcium alginate is a pH sensitive hydrogel stable in acidic media and soluble in basic media .
Cat. No.: HY-W094214
CAS No.: 7338-27-4
Synonyms: β-Methyl itaconate
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Monomethyl itaconate (β-Methyl itaconate) is a monomethyl ester derivative of Itaconic acid (HY-Y0520). Monomethyl itaconate can copolymerize with PEGMA to form pH-sensitive hydrogels .
Cat. No.: HY-DY1071
CAS No.: 312961-83-4
Solvent and concentration: DMSO: 10 mM
Cat. No.: HY-W110898
CAS No.: 2381-85-3
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Nile blue chloride is a highly fluorescent and photostable organic dye. Nile blue chloride and fluorescein isothiocyanate (FITC) can be used to construct a ratiometric pH sensitive probe for tracking the pH of the extracellular fluid between cancer cells in realtime. Nile Blue chloride has the potential for the research of nonlinear optics .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
