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parasitemia

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-16779B
    Fosravuconazole L-lysine ethanolate

    BMS-379224 L-lysine ethanolate; E-1224 L-lysine ethanolate

    		 Fungal Parasite Infection
    Fosravuconazole L-lysine ethanolate (BMS-379224 L-lysine ethanolate), a proagent of Ravuconazole, is an orally active broad spectrum antifungal agent. Fosravuconazole L-lysine ethanolate can be used for candidiasis, onychomycosis and parasitemia research .
    Fosravuconazole L-lysine ethanolate
  • HY-16779
    Fosravuconazole

    BMS-379224; E-1224

    		 Fungal Parasite Infection
    Fosravuconazole (BMS-379224), a proagent of Ravuconazole, is an orally active broad spectrum antifungal agent. Fosravuconazole can be used for candidiasis, onychomycosis and parasitemia research .
    Fosravuconazole
  • HY-148177
    Sutidiazine

    ZY-19489; MMV 253; AZ13721412

    		 Parasite Infection
    Sutidiazine (ZY-19489) is an orally active and antimalarial agent. Sutidiazine inhibits parasitemia-induced infection. Sutidiazine shows short half-lives (approximately 7 h) and an exposure effect .
    Sutidiazine
  • HY-136448
    SJ000025081

    		Parasite Infection
    SJ000025081 is a dihydropyridine and acts as a potent antimalarial agent. SJ000025081 results in an obvious suppression of the parasitemia in a murine malaria model infected with P. yoelii .
    SJ000025081
  • HY-120489
    A110

    		Parasite Infection
    A110 is the inhibitor for Cryptosporidium parvum inosine monophosphate dehydrogenase (CpIMPDH). A110 inhibits CpIMPDH in Toxoplasma gondii with IC50 of 18 nM. A110 exhibits pro-parasitic efficacy and cause parasitemia .
    A110
  • HY-B1896
    Piperaquine

    		Parasite Infection
    Piperaquine is a bisquinoline antimalarial agent. Piperaquine can be used in antimalarial research in combination with Artemisinin .
    Piperaquine
  • HY-149938
    Antimalarial agent 25

    		Parasite Infection
    Antimalarial agent 25 is an orally active 1,4-naphthoquinones derivative with antimalarial activity. Antimalarial agent 25 shows cytotoxicity against P. falciparum. Antimalarial agent 25 inhibits P. burghei induced parasitemia in vivo .
    Antimalarial agent 25
  • HY-149939
    Antimalarial agent 26

    		Parasite Infection
    Antimalarial agent 26 is an orally active 1,4-naphthoquinones derivative with antimalarial activities. Antimalarial agent 26 shows cytotoxicity against P. falciparum and selectivity over mammalian cell lines. Antimalarial agent 26 inhibits P. burghei induced parasitemia in vivo .
    Antimalarial agent 26
  • HY-161384
    WJM-715

    		Parasite Infection
    WJM-715 is an antimalarial agent with an EC50 of 0.015 μM by trageting STAR-related lipid transfer protein (PfSTART1) with a KD of 14 nM .
    WJM-715
  • HY-148178
    MMV688533

    		Parasite Infection
    MMV688533 is an antimalarial agent. MMV688533 interferes with intracellular trafficking, lipid utilization, and endocytosis pathways in Plasmodium falciparum. MMV688533 rapidly kills asexual blood-stage Plasmodium falciparum and Plasmodium vivax parasites in vitro and reduces parasitemia in a Plasmodium falciparum NSG mouse model. MMV688533 can be used for the research of malaria .
    MMV688533
  • HY-175305
    DMU759

    		Parasite Infection
    DMU759 is a Lysyl-tRNA synthetase 1 (KRS1) inhibitor. DMU759 has potent anti-kinetoplastid activity against Trypanosoma cruzi , Trypanosoma brucei and Leishmania donovani. DMU759 significantly reduces parasitemia in acute Chagas disease mice model. DMU759 can be used for parasitic infection like Chagas disease research .
    DMU759
  • HY-172953
    Insecticidal agent 24

    		Parasite Infection
    Insecticidal agent 24 is an orally active pyridylspiroindoline frontrunner. Insecticidal agent 24 has antiplasmodial activity (Pf NF54 IC50: 0.08 μM). Insecticidal agent 24 inhibits hERG activity (IC50: 6.5 μM). Insecticidal agent 24 reduces parasitemia in a humanized immunodeficient NSG mouse Plasmodium falciparum infection model .
    Insecticidal agent 24
  • HY-174325
    Antimalarial agent 50

    		Parasite Infection Inflammation/Immunology
    Antimalarial agent 50 is an antiplasmodial compound. Antimalarial agent 50 has an effect against Plasmodium berghei induced malaria infection in mice model. Antimalarial agent 50 can regulate oxidative stress and significantly reduce the levels of inflammatory factors. Antimalarial agent 50 can be used for the research of the malaria.
    Antimalarial agent 50
  • HY-147849
    JMI-105

    		Parasite Infection
    JMI-105 is a potent PfFP-2 (Plasmodium falciparum falcipain-2 protease) inhibitor. JMI-105 inhibits the growth of CQ S (3D7; IC50=8.8 µM) and CQ R (RKL-9; IC50=14.3 µM) strains of P. falciparum. JMI-105 significantly decreases parasitemia and prolonged host survival in a murine model with P. berghei ANKA infection. JMI-105 has the potential to be used as an anti-malarial agent .
    JMI-105
  • HY-183747
    Antitrypanosomal agent 32

    		Parasite Infection
    Antitrypanosomal agent 32 is a antitrypanosomal agent with nanomolar potency against multiple Trypanosoma cruzi strains, including CL-Brener, Y, Dm28c-Luc and Tulahuen. Antitrypanosomal agent 32 sustains inhibition of parasite growth after washing and reduces parasitemia levels in BALB/c mice. Antitrypanosomal agent 32 can be used for the research of trypanosome infection .
    Antitrypanosomal agent 32
  • HY-183574
    Antimalarial agent 62

    		Parasite Infection
    Antimalarial agent 62 is an orally active imidazopyridine-6-carboxamide antimalarial agent with a high resistance barrier. Antimalarial agent 62 kills trophozoite-stage Plasmodium ring forms, effectively clears dihydroartemisinin-induced dormant Plasmodium ring forms, and eliminates parasitemia in mice infected with Plasmodium yoelii. In AReBaR resistance omics screening, Antimalarial agent 62 is not affected by different target- and efflux-mediated resistance mutations and can withstand resistance selection. Antimalarial agent 62 has been applied to studies of malaria-related mechanisms .
    Antimalarial agent 62

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