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Results for "

parathyroid hormone

" in MedChemExpress (MCE) Product Catalog:

By Targets:	PTHR (25) Thyroid Hormone Receptor (29) Androgen Receptor (1) Apoptosis (2) Arrestin (2) Biochemical Assay Reagents (1) Calcium Channel (1) CaSR (15) Drug Derivative (1) Drug Metabolite (1) Environmental Pollutants (1) Farnesyl Transferase (1) Isotope-Labeled Compounds (4) NF-κB (3) PKC (1) Reference Standards (8) Sodium Phosphate Cotransporter (1) Src (1) VD/VDR (10)
By Research Areas:	Cancer (13) Endocrinology (34) Inflammation/Immunology (7) Metabolic Disease (37) Neurological Disease (3)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Targets Recommended: PTHR Thyroid Hormone Receptor GHR Nuclear Hormone Receptor 4A/NR4A TSH Receptor MCHR1 (GPR24) GHSR Hormone-Sensitive Lipase (HSL) GnRH Receptor

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P0059

Teriparatide Maximum Cited Publications 11 Publications Verification Human parathyroid hormone-(1-34); hPTH (1-34)	PTHR Thyroid Hormone Receptor	Others Cancer
Teriparatide (Human parathyroid hormone-(1-34)) is a PTH1 receptor agonist. Teriparatide (Human parathyroid hormone-(1-34)) can be used for osteoporosis research .

HY-17613

Evocalcet 3 Publications Verification KHK7580	CaSR	Metabolic Disease
Evocalcet (KHK7580) is an orally active calcium sensing receptor (CaSR) agonist. Evocalcet inhibits the secretion of parathyroid hormone (PTH) from parathyroid gland cells. Evocalcet can be used for the research of hyperparathyroidism .

HY-100856

PCO371	PTHR	Endocrinology
PCO371 is an orally active full agonist of parathyroid hormone receptor 1 (PTHR1), with no effect on PTH type 2 receptor.

HY-50919

Paricalcitol Maximum Cited Publications 15 Publications Verification	VD/VDR	Metabolic Disease Cancer
Paricalcitol, a vitamin D analogue, is a vitamin D receptor agonist, used for the prevention and treatment of secondary hyperparathyroidism (excessive secretion of parathyroid hormone) associated with chronic renal failure.

HY-108742

Abaloparatide 3 Publications Verification BA 058; BIM 44058	PTHR Arrestin	Metabolic Disease Cancer
Abaloparatide (BA 058) is a parathyroid hormone receptor 1 (PTHR1) analog. Abaloparatide also is a selective PTHR1 activator. Abaloparatide enhances Gs/cAMP signaling and β-arrestin recruitment. Abaloparatide enhances bone formation and cortical structure in mice. Abaloparatide has the potential for the research of osteoporosis .

HY-P1955A

Etelcalcetide hydrochloride 2 Publications Verification Velcalcetide hydrochloride; AMG 416 hydrochloride; KAI-4169 hydrochloride	CaSR	Endocrinology
Etelcalcetide hydrochloride (AMG 416 hydrochloride; KAI-4169 hydrochloride) is a synthetic calcimimetic as an activator of the calcium sensing receptor (CaSR). Etelcalcetide hydrochloride is effective in lowering parathyroid hormone (PTH) concentrations in patients receiving dialysis with secondary hyperparathyroidism receiving hemodialysis, which is promising for research in the field of secondary hyperparathyroidism and chronic kidney disease .

HY-14401

Encaleret CLTX-305; JTT-305; MK-5442	CaSR Thyroid Hormone Receptor	Metabolic Disease Inflammation/Immunology
Encaleret (CLTX-305) is an orally active antagonist of the calcium-sensing receptor (CaSR), with an IC₅₀ of 12 nM. Encaleret exerts its effect by inhibiting the excessive activity of functional gain-of-function CaSR variants, and can restore blood calcium levels, promote the secretion of parathyroid hormone, improve magnesium and phosphorus metabolism, and increase urinary calcium excretion. Encaleret can be used in the research of diseases such as osteoporosis and autosomal dominant hypocalcemia type 1 .

HY-A0245

Dihydrotachysterol	VD/VDR	Metabolic Disease
Dihydrotachysterol is a synthetic analog of vitamin D. Dihydrotachysterol can be used to for the research of hypocalcemia (lack of calcium in the blood) and hypoparathyroidism (lack of parathyroid hormone in the body) .

HY-15103

AH3960	PTHR Androgen Receptor	Cancer
AH3960 (compound 16c) is an antagonist of androgen receptor. AH3960 binds wild as well as T877 mutant type androgen receptors. AH3960 selectively inhibits T877 with an IC₅₀ value of 0.82 μM. AH3960 also serves as an agonist of parathyroid hormone receptor-1 (PTHR1) .

HY-P2279

Parathyroid hormone (1-34) (rat) 2 Publications Verification	Thyroid Hormone Receptor	Metabolic Disease Endocrinology
Parathyroid hormone (1-34) (rat) is a **parathyroid hormone*. Parathyroid* hormone (1-34) (rat) improves both cortical and cancellous bone structure. Parathyroid hormone (1-34) (rat) can be used for the research of osteoporosis .

HY-N2098

Obtusifolin 4 Publications Verification	NF-κB	Cancer
Obtusifolin, isolated from the seeds of Cassia obtusifolia, regulates the gene expression and production of MUC5AC mucin in airway epithelial cells via inhibiting NF-kB pathway . Obtusifolin suppresses phthalate esters-induced breast cancer bone metastasis by targeting parathyroid hormone-related protein .

HY-P2426

(D-Trp12,Tyr34)-pTH (7-34) amide (bovine)	Thyroid Hormone Receptor	Metabolic Disease
(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) is a potent and competitive antagonist of parathyroid hormone (PTH), with a K_i of 69 nM in bovine renal cortical membrane. (D-Trp12,Tyr34)-pTH (7-34) amide (bovine) can be used for growth and development regulation .

HY-P10909

Canvuparatide MBX 2109	Thyroid Hormone Receptor	Endocrinology
Canvuparatide (MBX 2109) is a prodrug for parathyroid hormone (PTH) peptide that releases the bioactive PTH[1-32] peptide agonist that retains a fatty acylated lysine (Lys33) at the C-terminus, thereby extending the halflife of Canvuparatide. Canvuparatide can be used for the symptoms of hypoparathyroidism such as hypocalcemia and hyperphosphatemia .

HY-148350

DS69910557	PTHR	Cancer
DS69910557 is a potent, selective and orally activehuman parathyroid hormone receptor 1 (hPTHR1) antagonist. DS69910557 has antagonistic activity for PTHR1 with an IC₅₀ value of 0.08 μM. DS69910557 can be used for the research of hyperparathyroidism, hypercalcemia of malignancy and osteoporosis .

HY-P1252

Parathyroid Hormone (1-34), bovine 3 Publications Verification	Thyroid Hormone Receptor	Metabolic Disease
Parathyroid Hormone (1-34), bovine is a potent parathyroid hormone (PTH) receptor agonist. Parathyroid Hormone (1-34), bovine increases calcium and inorganic phosphate levels in vivo. Parathyroid Hormone (1-34), bovine can be used for th reseach of osteoporosis .

HY-109106A

Upacicalcet sodium SK-1403; AJT240; PLS240	CaSR	Endocrinology
Upacicalcet sodium is a non-peptide calcimimetic that acts as a CaSR agonist (EC₅₀ = 10.8 nM). Upacicalcet sodium reduces serum intact parathyroid hormone (iPTH) and serum Ca ²⁺ levels, reducing hypocalcemia and gastrointestinal complications. Upacicalcet sodium sodium improves vascular calcification and bone disorders in the Adenine (HY-B0152)-induced secondary hyperparathyroidism (SHPT) rat model. Upacicalcet sodium sodium inhibits cortical pore formation and reduces bone fibrosis in rats with chronic kidney disease (CKD). Upacicalcet sodium is useful for studying SHPT .

HY-W145486

Calcium gluconate	Environmental Pollutants Biochemical Assay Reagents	Neurological Disease Metabolic Disease Inflammation/Immunology
Calcium gluconate is an orally effective calcium salt supplement . Calcium gluconate reduces elevated serum potassium, decreased serum calcium, and postoperative myalgia associated with succinylcholine administration. Calcium gluconate restores calcium homeostasis, skeletal integrity, bone mineralization and bone density, and maintains levels of parathyroid hormone, bone resorption markers and osteoclasts. Calcium gluconate reverses LPS (HY-D1056)-induced ERK phosphorylation, inflammatory cytokine release and acute lung injury, alleviates airway inflammatory damage and suppresses immune responses. Calcium gluconate can be used in research related to postoperative myalgia, osteoporosis/osteomalacia and acute lung injury .

HY-P4823

pTH (1-37) (human)	Thyroid Hormone Receptor	Metabolic Disease
pTH (1-37) (human) is a fragment of parathyroid hormone (PTH). pTH (1-37) (human) induces the cAMP formation and increases alkaline phosphatase activity. pTH (1-37) (human) increases growth, bone calcium content, and bone mineral density (BMD) in uremic animals. pTH (1-37) (human) has the potential for the research of osteoporosis .

HY-106608

Glutaurine Litoralon	Thyroid Hormone Receptor	Neurological Disease
Glutaurine containing glutamine and taurine residues is an orally active hormone of the parathyroid. Glutaurine, as a hormone, is isolated from parathyroid gland oxyphil cells. Glutaurine can be used for the research of antiepileptic and anti-amnesia .

HY-76585

Paricalcitol-d6	VD/VDR	Metabolic Disease
Paricalcitol-d₆ is the deuterium labeled Paricalcitol. Paricalcitol is a agent used for the prevention and treatment of secondary hyperparathyroidism (excessive secretion of parathyroid hormone) associated with chronic renal failure .

HY-108742A

Abaloparatide TFA 3 Publications Verification BA 058 TFA; BIM 44058 TFA	Arrestin PTHR	Metabolic Disease Endocrinology Cancer
Abaloparatide TFA (BA 058 TFA) is a parathyroid hormone receptor 1 (PTHR1) analogue. Abaloparatide TFA also is a selective PTHR1 activator. Abaloparatide TFA enhances Gs/cAMP signaling and β-arrestin recruitment. Abaloparatide TFA enhances bone formation and cortical structure in mice. Abaloparatide TFA has the potential for the research of osteoporosis .

HY-10002A

(1S)-Calcitriol 1α,25-Dihydroxy-3-epi-vitamin-D3	VD/VDR	Others
(1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3) is a natural metabolite of 1α,25-dihydroxyvitamin D₃ (1α,25(OH)₂D₃). (1S)-Calcitriol exhibits potent vitamin D receptor (VDR)-mediated actions such as inhibition of keratinocyte growth or suppression of parathyroid hormone secretion .

HY-P3075

pTH-Related Protein (1-34) (human,mouse,rat) pTHrP (1-34)	Thyroid Hormone Receptor	Inflammation/Immunology
pTH-Related Protein (1-34) (human, mouse, rat), a fragment of parathyroid hormone-related protein, is an anabolic agent. pTH-Related Protein (1-34) (human, mouse, rat) can be used for postmenopausal osteoporosis study .

HY-P2279A

Parathyroid hormone (1-34) (rat) acetate 2 Publications Verification	Thyroid Hormone Receptor	Metabolic Disease Endocrinology
Parathyroid hormone (1-34) (rat) (acetate) is a **parathyroid hormone*. Parathyroid* hormone (1-34) (rat) improves both cortical and cancellous bone structure. Parathyroid hormone (1-34) (rat) can be used for the research of osteoporosis .

HY-P10078

pTH (39-84) (human)	Thyroid Hormone Receptor Apoptosis	Endocrinology
pTH (39-84) (human) is the C-terminal fragment of parathyroid hormone (PTH). pTH (39-84) (human) increases Apoptosis. pTH (39-84) (human) can stimulate osteoclast formation .

HY-P0059A

Teriparatide acetate hydrate Human parathyroid hormone-(1-34) acetate hydrate; hPTH (1-34) acetate hydrate	PTHR Thyroid Hormone Receptor	Others Cancer
Teriparatide acetate hydrate (Human parathyroid hormone-(1-34) acetate hydrate) is a PTH1 receptor agonist. Teriparatide acetate hydrate (Human parathyroid hormone-(1-34) acetate hydrate) can be used for osteoporosis research .

HY-15830

25,26-Dihydroxyvitamin D3 25,26-Dihydroxycholecalciferol	VD/VDR Drug Metabolite Drug Derivative Calcium Channel	Metabolic Disease
25,26-Dihydroxyvitamin D3 (25,26-Dihydroxycholecalciferol) is a dihydroxylated derivative and metabolite of Vitamin D3 (HY-15398). 25,26-Dihydroxyvitamin D3 moderately increases serum calcium levels when the initial serum calcium level is low. 25,26-Dihydroxyvitamin D3 promotes intestinal calcium absorption in vitamin D-deficient rats fed a low-calcium diet. 25,26-Dihydroxyvitamin D3 is applicable to research related to osteomalacia .

HY-P1418A

DPC-AJ1951 TFA	Thyroid Hormone Receptor	Endocrinology
DPC-AJ1951 TFA, a 14 amino acid peptide that acts as a potent agonist of the parathyroid hormone (PTH)/PTH-related peptide receptor (PPR). And characterized the activity of DPC-AJ1951 TFA in ex vivo and in vivo assays of bone resorption .

HY-P4697A

pTH (44-68) (human) TFA	Thyroid Hormone Receptor	Endocrinology
pTH (44-68) (human) TFA is a fragment of human parathyroid hormone (pTH) that lacks the adenylate cyclase-stimulating activity of intact pTH. pTH (44-68) (human) TFA can be used to study the mechanism of action of pTH .

HY-17613R

Evocalcet (Standard) KHK7580 (Standard)	Reference Standards CaSR	Metabolic Disease
Evocalcet (Standard) is the analytical standard of Evocalcet. This product is intended for research and analytical applications. Evocalcet (KHK7580) is an orally active calcium sensing receptor (CaSR) agonist. Evocalcet inhibits the secretion of parathyroid hormone (PTH) from parathyroid gland cells. Evocalcet can be used for the research of hyperparathyroidism .

HY-B2097

Incadronate disodium YM 175; Bisphonal	Farnesyl Transferase	Metabolic Disease
Incadronate disodium (YM 175) is a bisphosphonate with strong inhibitory activity on bone resorption. Incadronate disodium indirectly stimulates renal 25-hydroxyvitamin D-1-hydroxylase by increasing circulating parathyroid hormone. Incadronate disodium, a cholesterol-lowering agent, is a potent inhibitor of rat liver microsomal squalene synthase (K_i=57 nM). Incadronate disodium inhibits sterol biosynthesis in mouse macrophage J774 cells (IC₅₀=64 μM). Incadronate disodium has the potential for malignant tumors research .

HY-16498

Tigapotide PCK-3145	Apoptosis	Cancer
Tigapotide (PCK-3145) is an anti-tumour peptide that reduces the development of skeletal metastases associated with prostate cancer. Tigapotide induces apoptosis and reduces tumour parathyroid hormone-related peptide (PTHrP) levels .

HY-P1955

Etelcalcetide Velcalcetide; AMG 416; KAI-4169	CaSR	Metabolic Disease
Etelcalcetide (AMG 416; KAI-4169) is a synthetic calcimimetic as an activator of the calcium sensing receptor (CaSR). Etelcalcetide is effective in lowering parathyroid hormone (PTH) concentrations in patients receiving dialysis with secondary hyperparathyroidism receiving hemodialysis, which is promising for research in the field of secondary hyperparathyroidism and chronic kidney disease .

HY-P4857

pTH-Related Protein (7-34) amide (human, mouse, rat)	Thyroid Hormone Receptor	Endocrinology
pTH-Related Protein (7-34) amide (human, mouse, rat) is a potent antagonist of parathyroid hormone (PTH) .

HY-10003AR

1α-Hydroxy-3-epi-vitamin D3 (Standard)	Thyroid Hormone Receptor Reference Standards	Metabolic Disease
1α-Hydroxy-3-epi-vitamin D3 (Standard) is the analytical standard of 1α-Hydroxy-3-epi-vitamin D3 (HY-10003A). This product is intended for research and analytical applications. 1α-Hydroxy-3-epi-vitamin D3, a natural metabolite of 1alpha,25-dihydroxyvitamin D3, is a potent suppressor of parathyroid hormone (PTH) secretion .

HY-113918

SW-106	PTHR	Metabolic Disease
SW-106 is a parathyroid hormone receptor 1 (PTHR1) antagonist. SW106 antagonizes PTHR1-mediated cAMP signaling induced by the peptide analog, M-PTH (1-11), as well as by the native PTH (1-9) sequence, as tethered to the extracellular end of transmembrane domain (TMD) helix-1 of the receptor. SW-106 can be used for the research of metabolic disease .

HY-P2510

Parathyroid Hormone (1-34), human, biotinylated	Thyroid Hormone Receptor	Metabolic Disease
Parathyroid Hormone (1-34), human, biotinylated is a probe for the parathyroid hormone receptor, can be used for analyzing the interaction between parathyroid hormone and parathyroid hormone receptors in living cells and for purifying hormone-receptor complexes with affinity columns .

HY-131206

DS37571084	PTHR	Metabolic Disease Endocrinology
DS37571084 is an orally active and potent antagonist of the parathyroid hormone type 1 receptor (PTHR1), with an IC₅₀ value of 0.17 μM. DS37571084 can be used for the study of hyperparathyroidism .

HY-P4856

pTH-Related Protein (1-40) (human, mouse, rat)	PTHR PKC	Endocrinology
pTH-Related Protein (1-40) (human, mouse, rat) stimulates calcium uptake in rat intestinal cells through PTHR1 receptor and PKCα/β signaling pathways. pTH-Related Protein (1-40) up-regulates parathyroid hormone 1 receptor (PTHR1) protein, four transcellular calcium transporters, potential vanillin member 6 (TRPV6), calcium-binding protein-D9K (CaBP-D9k), sodium-calcium Exchanger 1 (NCX1) and plasma membrane calcium ATPase 1 (PMCA1) .

HY-P4849

pTH-Related Protein (1-37) (human, mouse, rat)	PTHR	Others
pTH-Related Protein (1-37) (human, mouse, rat), the peptide analogue of pTH-Related Protein (pTHrP). pTHrP refers to parathyroid-hormone-related protein, involved in physiological regulation of bone formation .

HY-P4798

Osteostatin (1-5) amide (human, bovine, dog, horse, mouse, rabbit, rat) Human PTHrP(107-111) amide	PTHR	Others
Osteostatin (1-5) amide (human, bovine, dog, horse, mouse, rabbit, rat) (Human PTHrP (107-111) amide) is a C-terminal parathyroid hormone-related protein fragment that can inhibit bone resorption .

HY-176946

PTH1R agonist 4	PTHR	Metabolic Disease
PTH1R agonist 4 (Example 63) is a parathyroid hormone 1 receptor (PTH1R) agonist with a pEC₅₀ value greater than 7. PTH1R agonist 4 can be used for the study of bone diseases, such as osteoporosis .

HY-179475

KP-2067	CaSR	Endocrinology
KP-2067 is a form of the CaSR agonist peptide. KP-2067 can result in dose-dependent activation of CaSR in HEK293T overexpressing hCaSR cell line, with an EC₅₀ of 18.4 μM. KP-2067 significantly reduces plasma parathyroid hormone in rat model .

HY-120398

CH5447240	PTHR	Endocrinology
CH5447240 is an agonist for parathyroid hormone receptor 1 (PTHR1), that inhibits human PTHR1 with an EC₅₀ of 12 μM. CH5447240 exhibits good metabolic stability in human liver microsomes. CH5447240 increases serum calcium levels in rats. CH5447240 can be used in research about hypoparathyroidism .

HY-14752

Ronacaleret SB 751689	CaSR	Metabolic Disease Endocrinology
Ronacaleret (SB 751689) is an orally active, potent, and selective calcium-sensing receptor (CaSR) antagonist that stimulates endogenous parathyroid hormone release from the parathyroid glands. Ronacaleret (SB 751689) is used for the study of postmenopausal osteoporosis .

HY-15104

Ronacaleret hydrochloride SB 751689A	CaSR	Metabolic Disease Endocrinology
Ronacaleret hydrochloride (SB 751689A) is an orally active, potent, and selective calcium-sensing receptor (CaSR) antagonist that stimulates endogenous parathyroid hormone release from the parathyroid glands. Ronacaleret hydrochloride (SB 751689A) is used for the study of postmenopausal osteoporosis .

HY-10003A

1α-Hydroxy-3-epi-vitamin D3	Thyroid Hormone Receptor	Metabolic Disease
1α-Hydroxy-3-epi-vitamin D3, a natural metabolite of 1alpha,25-dihydroxyvitamin D3, is a potent suppressor of parathyroid hormone (PTH) secretion .

HY-P1252A

Parathyroid Hormone (1-34), bovine TFA	Thyroid Hormone Receptor	Metabolic Disease
Parathyroid Hormone (1-34), bovine TFA is a potent parathyroid hormone (PTH) receptor agonist. Parathyroid Hormone (1-34), bovine increases calcium and inorganic phosphate levels in vivo. Parathyroid Hormone (1-34), bovine can be used for th reseach of osteoporosis .

HY-109106

Upacicalcet SK-1403 free acid; AJT240 free acid; PLS240 free acid	CaSR	Endocrinology
Upacicalcet is a non-peptide calcimimetic that acts as a CaSR agonist (EC₅₀ = 10.8 nM). Upacicalcet reduces serum intact parathyroid hormone (iPTH) and serum Ca2+ levels, reducing hypocalcemia and gastrointestinal complications. Upacicalcet improves vascular calcification and bone disorders in the Adenine (HY-B0152)-induced secondary hyperparathyroidism (SHPT) rat model. Upacicalcet inhibits cortical pore formation and reduces bone fibrosis in rats with chronic kidney disease (CKD). Upacicalcet is useful for studying SHPT .

HY-176944

PTH1R agonist 2	PTHR	Metabolic Disease Endocrinology
PTH1R agonist 2 (example 3) is a parathyroid hormone 1 receptor (PTH1R) agonist. PTH1R agonist 2 can be used for research of hypoparathyroidism and osteoporosis .

Cat. No.	Product Name	Type

HY-W145486

Calcium gluconate

Biochemical Assay Reagents

Calcium gluconate is an orally effective calcium salt supplement . Calcium gluconate reduces elevated serum potassium, decreased serum calcium, and postoperative myalgia associated with succinylcholine administration. Calcium gluconate restores calcium homeostasis, skeletal integrity, bone mineralization and bone density, and maintains levels of parathyroid hormone, bone resorption markers and osteoclasts. Calcium gluconate reverses LPS (HY-D1056)-induced ERK phosphorylation, inflammatory cytokine release and acute lung injury, alleviates airway inflammatory damage and suppresses immune responses. Calcium gluconate can be used in research related to postoperative myalgia, osteoporosis/osteomalacia and acute lung injury .

Cat. No.	Product Name	Target	Research Area

HY-P0059

Teriparatide Maximum Cited Publications 11 Publications Verification Human parathyroid hormone-(1-34); hPTH (1-34)	PTHR Thyroid Hormone Receptor	Others Cancer
Teriparatide (Human parathyroid hormone-(1-34)) is a PTH1 receptor agonist. Teriparatide (Human parathyroid hormone-(1-34)) can be used for osteoporosis research .

HY-108742

Abaloparatide 3 Publications Verification BA 058; BIM 44058	PTHR Arrestin	Metabolic Disease Cancer
Abaloparatide (BA 058) is a parathyroid hormone receptor 1 (PTHR1) analog. Abaloparatide also is a selective PTHR1 activator. Abaloparatide enhances Gs/cAMP signaling and β-arrestin recruitment. Abaloparatide enhances bone formation and cortical structure in mice. Abaloparatide has the potential for the research of osteoporosis .

HY-P1955A

Etelcalcetide hydrochloride 2 Publications Verification Velcalcetide hydrochloride; AMG 416 hydrochloride; KAI-4169 hydrochloride	CaSR	Endocrinology
Etelcalcetide hydrochloride (AMG 416 hydrochloride; KAI-4169 hydrochloride) is a synthetic calcimimetic as an activator of the calcium sensing receptor (CaSR). Etelcalcetide hydrochloride is effective in lowering parathyroid hormone (PTH) concentrations in patients receiving dialysis with secondary hyperparathyroidism receiving hemodialysis, which is promising for research in the field of secondary hyperparathyroidism and chronic kidney disease .

HY-P2279

Parathyroid hormone (1-34) (rat) 2 Publications Verification	Thyroid Hormone Receptor	Metabolic Disease Endocrinology
Parathyroid hormone (1-34) (rat) is a **parathyroid hormone*. Parathyroid* hormone (1-34) (rat) improves both cortical and cancellous bone structure. Parathyroid hormone (1-34) (rat) can be used for the research of osteoporosis .

HY-P2426

(D-Trp12,Tyr34)-pTH (7-34) amide (bovine)	Thyroid Hormone Receptor	Metabolic Disease
(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) is a potent and competitive antagonist of parathyroid hormone (PTH), with a K_i of 69 nM in bovine renal cortical membrane. (D-Trp12,Tyr34)-pTH (7-34) amide (bovine) can be used for growth and development regulation .

HY-P10909

Canvuparatide MBX 2109	Thyroid Hormone Receptor	Endocrinology
Canvuparatide (MBX 2109) is a prodrug for parathyroid hormone (PTH) peptide that releases the bioactive PTH[1-32] peptide agonist that retains a fatty acylated lysine (Lys33) at the C-terminus, thereby extending the halflife of Canvuparatide. Canvuparatide can be used for the symptoms of hypoparathyroidism such as hypocalcemia and hyperphosphatemia .

HY-P1252

Parathyroid Hormone (1-34), bovine 3 Publications Verification	Thyroid Hormone Receptor	Metabolic Disease
Parathyroid Hormone (1-34), bovine is a potent parathyroid hormone (PTH) receptor agonist. Parathyroid Hormone (1-34), bovine increases calcium and inorganic phosphate levels in vivo. Parathyroid Hormone (1-34), bovine can be used for th reseach of osteoporosis .

HY-P4823

pTH (1-37) (human)	Thyroid Hormone Receptor	Metabolic Disease
pTH (1-37) (human) is a fragment of parathyroid hormone (PTH). pTH (1-37) (human) induces the cAMP formation and increases alkaline phosphatase activity. pTH (1-37) (human) increases growth, bone calcium content, and bone mineral density (BMD) in uremic animals. pTH (1-37) (human) has the potential for the research of osteoporosis .

HY-P10277

Palopegteriparatide Transcon PTH; ACP-014	Peptides	Endocrinology
Palopegteriparatide (Transcon PTH) is a prodrug of parathyroid hormone PTH 1-34, which can maintain normal and stable calcium concentrations without the need for calcium and active vitamin D replacement. Palopegteriparatide can be used in research on hypoparathyroidism .

HY-108742A

Abaloparatide TFA 3 Publications Verification BA 058 TFA; BIM 44058 TFA	Arrestin PTHR	Metabolic Disease Endocrinology Cancer
Abaloparatide TFA (BA 058 TFA) is a parathyroid hormone receptor 1 (PTHR1) analogue. Abaloparatide TFA also is a selective PTHR1 activator. Abaloparatide TFA enhances Gs/cAMP signaling and β-arrestin recruitment. Abaloparatide TFA enhances bone formation and cortical structure in mice. Abaloparatide TFA has the potential for the research of osteoporosis .

HY-P3075

pTH-Related Protein (1-34) (human,mouse,rat) pTHrP (1-34)	Thyroid Hormone Receptor	Inflammation/Immunology
pTH-Related Protein (1-34) (human, mouse, rat), a fragment of parathyroid hormone-related protein, is an anabolic agent. pTH-Related Protein (1-34) (human, mouse, rat) can be used for postmenopausal osteoporosis study .

HY-P2279A

Parathyroid hormone (1-34) (rat) acetate 2 Publications Verification	Thyroid Hormone Receptor	Metabolic Disease Endocrinology
Parathyroid hormone (1-34) (rat) (acetate) is a **parathyroid hormone*. Parathyroid* hormone (1-34) (rat) improves both cortical and cancellous bone structure. Parathyroid hormone (1-34) (rat) can be used for the research of osteoporosis .

HY-P10078

pTH (39-84) (human)	Thyroid Hormone Receptor Apoptosis	Endocrinology
pTH (39-84) (human) is the C-terminal fragment of parathyroid hormone (PTH). pTH (39-84) (human) increases Apoptosis. pTH (39-84) (human) can stimulate osteoclast formation .

HY-P1418A

DPC-AJ1951 TFA	Thyroid Hormone Receptor	Endocrinology
DPC-AJ1951 TFA, a 14 amino acid peptide that acts as a potent agonist of the parathyroid hormone (PTH)/PTH-related peptide receptor (PPR). And characterized the activity of DPC-AJ1951 TFA in ex vivo and in vivo assays of bone resorption .

HY-P4697A

pTH (44-68) (human) TFA	Thyroid Hormone Receptor	Endocrinology
pTH (44-68) (human) TFA is a fragment of human parathyroid hormone (pTH) that lacks the adenylate cyclase-stimulating activity of intact pTH. pTH (44-68) (human) TFA can be used to study the mechanism of action of pTH .

HY-16498

Tigapotide PCK-3145	Apoptosis	Cancer
Tigapotide (PCK-3145) is an anti-tumour peptide that reduces the development of skeletal metastases associated with prostate cancer. Tigapotide induces apoptosis and reduces tumour parathyroid hormone-related peptide (PTHrP) levels .

HY-P1955

Etelcalcetide Velcalcetide; AMG 416; KAI-4169	CaSR	Metabolic Disease
Etelcalcetide (AMG 416; KAI-4169) is a synthetic calcimimetic as an activator of the calcium sensing receptor (CaSR). Etelcalcetide is effective in lowering parathyroid hormone (PTH) concentrations in patients receiving dialysis with secondary hyperparathyroidism receiving hemodialysis, which is promising for research in the field of secondary hyperparathyroidism and chronic kidney disease .

HY-P4857

pTH-Related Protein (7-34) amide (human, mouse, rat)	Thyroid Hormone Receptor	Endocrinology
pTH-Related Protein (7-34) amide (human, mouse, rat) is a potent antagonist of parathyroid hormone (PTH) .

HY-P2510

Parathyroid Hormone (1-34), human, biotinylated	Thyroid Hormone Receptor	Metabolic Disease
Parathyroid Hormone (1-34), human, biotinylated is a probe for the parathyroid hormone receptor, can be used for analyzing the interaction between parathyroid hormone and parathyroid hormone receptors in living cells and for purifying hormone-receptor complexes with affinity columns .

HY-P4856

pTH-Related Protein (1-40) (human, mouse, rat)	PTHR PKC	Endocrinology
pTH-Related Protein (1-40) (human, mouse, rat) stimulates calcium uptake in rat intestinal cells through PTHR1 receptor and PKCα/β signaling pathways. pTH-Related Protein (1-40) up-regulates parathyroid hormone 1 receptor (PTHR1) protein, four transcellular calcium transporters, potential vanillin member 6 (TRPV6), calcium-binding protein-D9K (CaBP-D9k), sodium-calcium Exchanger 1 (NCX1) and plasma membrane calcium ATPase 1 (PMCA1) .

HY-P4849

pTH-Related Protein (1-37) (human, mouse, rat)	PTHR	Others
pTH-Related Protein (1-37) (human, mouse, rat), the peptide analogue of pTH-Related Protein (pTHrP). pTHrP refers to parathyroid-hormone-related protein, involved in physiological regulation of bone formation .

HY-P4798

Osteostatin (1-5) amide (human, bovine, dog, horse, mouse, rabbit, rat) Human PTHrP(107-111) amide	PTHR	Others
Osteostatin (1-5) amide (human, bovine, dog, horse, mouse, rabbit, rat) (Human PTHrP (107-111) amide) is a C-terminal parathyroid hormone-related protein fragment that can inhibit bone resorption .

HY-179475

KP-2067	CaSR	Endocrinology
KP-2067 is a form of the CaSR agonist peptide. KP-2067 can result in dose-dependent activation of CaSR in HEK293T overexpressing hCaSR cell line, with an EC₅₀ of 18.4 μM. KP-2067 significantly reduces plasma parathyroid hormone in rat model .

HY-P1252A

Parathyroid Hormone (1-34), bovine TFA	Thyroid Hormone Receptor	Metabolic Disease
Parathyroid Hormone (1-34), bovine TFA is a potent parathyroid hormone (PTH) receptor agonist. Parathyroid Hormone (1-34), bovine increases calcium and inorganic phosphate levels in vivo. Parathyroid Hormone (1-34), bovine can be used for th reseach of osteoporosis .

HY-P1418

DPC-AJ1951	Thyroid Hormone Receptor	Endocrinology
DPC-AJ1951, a 14 amino acid peptide that acts as a potent agonist of the parathyroid hormone (PTH)/PTH-related peptide receptor (PPR). And characterized the activity of DPC-AJ1951 in ex vivo and in vivo assays of bone resorption .

HY-P4692

pTH (1-44) (human)	Thyroid Hormone Receptor	Endocrinology
pTH (1-44) (human) is apTH ((Human parathyroid hormone) fragment.

HY-P4690

pTH (13-34) (human)	Thyroid Hormone Receptor	Endocrinology
pTH (13-34) (human) is apTH ((Human parathyroid hormone) fragment.

HY-P4697

pTH (44-68) (human)	Thyroid Hormone Receptor	Endocrinology
pTH (44-68) (human) is apTH ((Human parathyroid hormone) fragment.

HY-P4700

pTH (53-84) (human)	Thyroid Hormone Receptor	Endocrinology
pTH (53-84) (human) is apTH ((Human parathyroid hormone) fragment.

HY-P4696

pTH (3-34) (bovine)	Thyroid Hormone Receptor	Endocrinology
pTH (3-34) (bovine) is apTH ((Human parathyroid hormone) fragment.

HY-P4762

(TYR34)-PTH (7-34) AMIDE (BOVINE)	Peptides	Others
(TYR34)-PTH (7-34) AMIDE (BOVINE) is a peptide derivative of Parathyroid Hormone (PTH) .

HY-P4715

(Tyr36)-pTH-Related Protein (1-36) (human, mouse, rat)	PTHR	Endocrinology
(Tyr36)-pTH-Related Protein (1-36) (human, mouse, rat) is a peptide and can be used as a parathyroid hormone (PTH) receptor ligand .

HY-P4800

Osteostatin (human) Human PTHrP(107-139)	Thyroid Hormone Receptor	Metabolic Disease Inflammation/Immunology
Osteostatin (human), a fragment of parathyroid hormone-related protein (PTHrP) 107-139, promotes bone repair in animal models of bone defects and prevents bone erosion in inflammatory arthritis .

HY-P10309

[Nle8,18,Tyr34]-pTH (3-34) amide (human) [Nle8'18,Tyr34]hPTH (3-34) amide	PTHR	Endocrinology
[Nle8,18,Tyr34]-pTH (3-34) amide human ([Nle8,18,Tyr34]hPTH (3-34) amide) is a parathyroid hormone (PTH) analog .

HY-P4684

Osteostatin PTHrP (107–111)	PTHR	Inflammation/Immunology
Osteostatin, a fragment of parathyroid hormone-related protein (PTHrP) 107-111, promotes bone repair in animal models of bone defects and prevents bone erosion in inflammatory arthritis, inhibits collagen-induced arthritis and inhibits osteoclastic bone resorption directly. Osteostatin can be used for inflammation and immunology research .

HY-P10313

[Nle8,18,Tyr34]-pTH (3-34) amide (bovine) [Nle8'18,Tyr34]bPTH (3-34) amide	Peptides	Others
[Nle8,18,Tyr34]-pTH (3-34) amide (bovine) ([Nle8'18,Tyr34]bPTH (3-34) amide) is an analogue of parathyroid hormone (PTH), and is a competitive inhibitor of PTH-stimulated biological responses in vitro .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N2098

Obtusifolin 4 Publications Verification	Seeds of Cassia tora Linn. Quinones other families Classification of Application Fields Leguminosae Anthraquinones Phenols Polyphenols Plants Disease Research Fields Source Classification Cancer	NF-κB
Obtusifolin, isolated from the seeds of Cassia obtusifolia, regulates the gene expression and production of MUC5AC mucin in airway epithelial cells via inhibiting NF-kB pathway . Obtusifolin suppresses phthalate esters-induced breast cancer bone metastasis by targeting parathyroid hormone-related protein .

HY-15830

25,26-Dihydroxyvitamin D3 25,26-Dihydroxycholecalciferol	Structural Classification Natural Products Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Source Classification	VD/VDR Drug Metabolite Drug Derivative Calcium Channel
25,26-Dihydroxyvitamin D3 (25,26-Dihydroxycholecalciferol) is a dihydroxylated derivative and metabolite of Vitamin D3 (HY-15398). 25,26-Dihydroxyvitamin D3 moderately increases serum calcium levels when the initial serum calcium level is low. 25,26-Dihydroxyvitamin D3 promotes intestinal calcium absorption in vitamin D-deficient rats fed a low-calcium diet. 25,26-Dihydroxyvitamin D3 is applicable to research related to osteomalacia .

HY-N2098R

Obtusifolin (Standard)	Seeds of Cassia tora Linn. Quinones Structural Classification other families Leguminosae Anthraquinones Phenols Polyphenols Plants Source Classification	Reference Standards NF-κB
Obtusifolin (Standard) is the analytical standard of Obtusifolin. This product is intended for research and analytical applications. Obtusifolin, isolated from the seeds of Cassia obtusifolia, regulates the gene expression and production of MUC5AC mucin in airway epithelial cells via inhibiting NF-kB pathway . Obtusifolin suppresses phthalate esters-induced breast cancer bone metastasis by targeting parathyroid hormone-related protein .

Species:	Human (5) Rat (1) Cynomolgus (2)
Tag:	His (5) Tag Free (1) GST (1) Fc (1)
Source:	HEK293 (4) E. coli Cell-free (1) E. coli (3)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P705535

	PTH1R Protein, Cynomolgus (Cell-Free, His) parathyroid hormone; parathyroid hormone-related peptide receptor; PTH; PTHrP type I receptor; parathyroid hormone 1 receptor	Cynomolgus	E. coli Cell-free

HY-P705972

	PTH Protein, Cynomolgus (HEK293, hFc) parathyroid hormone; PTH; Parathyrin	Cynomolgus	HEK293

HY-P73686

	PTH Protein, Human (GST) parathyroid hormone; PTH; Parathormone; Parathyrin	Human	E. coli
	PTH Protein, or parathyroid hormone, raises calcium levels by dissolving bone salts and inhibiting kidney excretion. It also stimulates [1-14C]-2-deoxy-D-glucose transport and glycogen synthesis in osteoblastic cells, interacting with the PTH1R receptor and binding to its N-terminal extracellular domain for these effects. PTH Protein, Human (GST) is the recombinant human-derived PTH protein, expressed by E. coli , with N-GST labeled tag.

HY-P71060

	PTH Protein, Human (HEK293, His) parathyroid hormone; PTH; Parathormone; Parathyrin; PTH	Human	HEK293
	PTH Protein, or parathyroid hormone, raises calcium levels by dissolving bone salts and inhibiting kidney excretion. It also stimulates [1-14C]-2-deoxy-D-glucose transport and glycogen synthesis in osteoblastic cells, interacting with the PTH1R receptor and binding to its N-terminal extracellular domain for these effects. PTH Protein, Human (HEK293, His) is the recombinant human-derived PTH protein, expressed by HEK293 , with N-8*His labeled tag.

HY-P71244

	PTH1R Protein, Human (HEK293, His) parathyroid hormone/parathyroid hormone-related peptide receptor; PTH/PTHrP type I receptor; PTH/PTHr receptor; parathyroid hormone 1 receptor; PTH1 receptor; PTH1R	Human	HEK293
	PTH1R Protein, Human (HEK 293, His) is a recombinant PTH1R protein with a His-Flag. PTH1R plays an important role in skeletal development and homeostasis.

HY-P705968

	PTH1R Protein, Rat (HEK293, His) parathyroid hormone/parathyroid hormone-related peptide receptor; PTH/PTHrP type I receptor (PTH/PTHr receptor); parathyroid hormone 1 receptor (PTH1 receptor); Pth1r; Pthr, Pthr1	Rat	HEK293

HY-P702562

	PTHrP Protein, Human (His) parathyroid hormone related protein; parathyroid hormone-like protein; parathyroid like protein; PLP; PTH related protein; PTH-rP; PTHLH; PTHR; PTHR_HUMAN; PTHrP; PTHrP	Human	E. coli
	The PTHrP protein is a key neuroendocrine peptide that regulates multiple cellular processes, including growth, development, migration, differentiation, and survival. It plays an integral role in epithelial calcium transport and key developmental events such as endochondral bone development, mammary gland, and tooth formation. PTHrP Protein, Human (His) is the recombinant human-derived PTHrP protein, expressed by E. coli , with N-6*His labeled tag.

HY-P7112

	PTH Protein, Human rHuPTH; Parathormone; Parathyrin	Human	E. coli
	PTH Protein, Human is a major regulator of mineral ion metabolism.

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Cat. No.	Product Name	Chemical Structure

HY-76585

Paricalcitol-d6
Paricalcitol-d₆ is the deuterium labeled Paricalcitol. Paricalcitol is a agent used for the prevention and treatment of secondary hyperparathyroidism (excessive secretion of parathyroid hormone) associated with chronic renal failure .

HY-17613S

Evocalcet-d4
Evocalcet-d₄ (KHK7580-d₄) is deuterium labeled Evocalcet. Evocalcet (KHK7580) is an orally active calcium sensing receptor (CaSR) agonist. Evocalcet inhibits the secretion of parathyroid hormone (PTH) from parathyroid gland cells. Evocalcet can be used for the research of hyperparathyroidism .

HY-P0059S

Teriparatide-d10
Teriparatide-d₁₀ (Human parathyroid hormone-(1-34)-d₁₀) is the deuterium labeled Teriparatide (HY-P0059). Teriparatide (Human parathyroid hormone-(1-34)) is a PTH1 receptor agonist. Teriparatide (Human parathyroid hormone-(1-34)) can be used for osteoporosis research .

HY-10002AS2

(1S)-Calcitriol-d6

(1S)-Calcitriol-d₆ (1α,25-Dihydroxy-3-epi-vitamin D3-d₆) is the deuterium labeled (1S)-Calcitriol (HY-10002A). (1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3) is a natural metabolite of 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3). (1S)-Calcitriol exhibits potent vitamin D receptor (VDR)-mediated actions such as inhibition of keratinocyte growth or suppression of parathyroid hormone secretion .

HY-10002AS

(1S)-Calcitriol-d3

(1S)-Calcitriol-d₃ (1α,25-Dihydroxy-3-epi-vitamin D3-d₃) is the deuterium labeled (1S)-Calcitriol (HY-10002A). (1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3) is a natural metabolite of 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3). (1S)-Calcitriol exhibits potent vitamin D receptor (VDR)-mediated actions such as inhibition of keratinocyte growth or suppression of parathyroid hormone secretion .

Host:	Mouse (5) Rabbit (3)
Reactivity:	Human (8)
Application:	IHC-P (6) ICC/IF (5) IF-Tissue (1) IP (2) IHC-F (1) WB (3) FC (2) ELISA (5)
Isotype:	IgG (3) IgG1 (3) IgG2b (2)
Conjugation:	Non-conjugated (8)
Clonality:	Monoclonal (5) Monoclonal Antibody (1) Recombinant (3)
Modification:	Unmodified (6)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P85339

	Parathyroid Hormone Antibody (YA5031) PTH; parathyroid hormone; PTH; Parathormone; Parathyrin	WB, IHC-P, IHC-F, IF-Tissue	Human
	Parathyroid Hormone Antibody (YA5031) is a Rabbit-derived and non-conjugated monoclonal antibody, targeting to Parathyroid Hormone.

HY-P81707

	Parathyroid Hormone Receptor 1 Antibody (YA1452) PTH1R; PTHR; PTHR1; parathyroid hormone/parathyroid hormone-related peptide receptor; PTH/PTHrP type I receptor; PTH/PTHr receptor; parathyroid hormone 1 receptor; PTH1 receptor	WB, IP	Human
	Parathyroid Hormone Receptor 1 Antibody (YA1452) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Parathyroid Hormone Receptor 1.

HY-P85340

	Parathyroid Hormone Receptor 1 Antibody (YA5032) PTH1R; PTHR; PTHR1; parathyroid hormone/parathyroid hormone-related peptide receptor; PTH/PTHrP type I receptor; PTH/PTHr receptor; parathyroid hormone 1 receptor; PTH1 receptor	WB, IP	Human
	Parathyroid Hormone Receptor 1 Antibody (YA5032) is a Rabbit-derived and non-conjugated monoclonal antibody, targeting to Parathyroid Hormone Receptor 1.

HY-P86009

	Parathyroid Hormone Antibody (YA5701)	IHC-P, ICC/IF, ELISA	Human
	Parathyroid Hormone Antibody (YA5701) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Parathyroid Hormone.

HY-P83905

	Parathyroid Hormone Antibody (YA3602) FIH1; PTH1	IHC-P, ICC/IF, FC, ELISA	Human
	Parathyroid Hormone Antibody (YA3602) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to Parathyroid Hormone.

HY-P83905A

	Parathyroid Hormone Antibody (YA3602)(PBS only) FIH1; PTH1	IHC-P, ICC/IF, FC, ELISA	Human
	Parathyroid Hormone Antibody (YA3602) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to Parathyroid Hormone.

HY-P84478

	Parathyroid Hormone Receptor 1 Antibody (YA4175) PFE; PTHR; PTHR1; MGC138426; MGC138452; PTH1R	IHC-P, ICC/IF, ELISA	Human
	Parathyroid Hormone Receptor 1 Antibody (YA4175) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Parathyroid Hormone Receptor 1.

HY-P84478A

	Parathyroid Hormone Receptor 1 Antibody (YA4175)(PBS only) PFE; PTHR; PTHR1; MGC138426; MGC138452; PTH1R	IHC-P, ICC/IF, ELISA	Human
	Parathyroid Hormone Receptor 1 Antibody (YA4175) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Parathyroid Hormone Receptor 1.

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parathyroid hormone

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