6559 Results for "

peg

" in MedChemExpress (MCE) Product Catalog:
Products (6559)

6559 Results for "peg" in MCE Product Catalog:

212
212 Publications Verification
Cat. No.: HY-Y0873
CAS No.: 25322-68-3
Synonyms: Polyethylene glycol 300
PEG300 (Polyethylene glycol 300), a neutral polymer of molecular weight 300, is a water-soluble, low immunogenic and biocompatible polymer formed by repeating units of ethylene glycol .
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38
38 Cited Publications
Cat. No.: HY-Y0873A
CAS No.: 25322-68-3
Synonyms: Polyethylene glycol 400
PEG400 is a strongly hydrophilic polyethylene glycol used as an excellent solvent for a large number of substances. PEG400 is widely used in a variety of pharmaceutical formulations.
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24
24 Cited Publications
Cat. No.: HY-Y1890
CAS No.: 61791-12-6
Synonyms: Polyoxyethylene(40) Castor Oil; peg-40 Castor Oil
Cremophor EL-40, a polyoxyethylene castor oil derivative, is a nonionic surfactant. Cremophor EL-40 is widely employed to improve dissolution and delivery of agents .
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19
19 Cited Publications
Cat. No.: HY-138300
CAS No.: 1849616-42-7
Purity:  99.93%
ALC-0159, a polyethylene glycol (PEG) lipid conjugate, could be used as vaccine excipient .
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16
16 Cited Publications
Cat. No.: HY-142979
CAS No.: 892144-24-0
Purity:  99.95%
Synonyms: (C2H4O)nC42H82NO10P
DSPE-PEG 2000 is a PEG polymer containing DSPE and amine end groups. DSPE-PEG 2000 can be used to form micelles as nanoparticles for drug delivery .
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8
8 Cited Publications
Cat. No.: HY-D1005
CAS No.: 9003-11-6
Synonyms: peg-PPG-peg, 12600 (Average Mn)
Poloxamer 407 (F127) is a nonionic surfactant that is 100% active and relatively non-toxic to cells at low concentrations, and frequently used with dye AM esters such as Indo-1 AM, Fura-2 AM, Calcein AM, Fluo-3 AM, Fluo-4 AM, Quest Fluo-8 AM and Quest Rhod-4 AM, etc. to improve their water solubility. Poloxamer 407 is also a lipoprotein lipase inhibitor .
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6
6 Cited Publications
Cat. No.: HY-130809
CAS No.: 1255942-07-4
Purity:  99.40%
Research Areas:  

Cancer

DBCO-PEG4-Biotin is an azadibenzocyclooctyne-biotin derivative containing a biotin group and 4 PEGs. DBCO-PEG4-Biotin is a versatile biotinylation reagent used for the introduction of a biotin moiety to azide-labeled biomolecules via copper-free strain-promoted alkyne-azide click chemistry (SPAAC) reaction . DBCO-PEG4-Biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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5
5 Cited Publications
Cat. No.: HY-125878
CAS No.: 2381320-35-8
Purity:  99.89%
Synonyms: SGK3-PROTAC1
Target:  

PROTACs SGK

Research Areas:  

Cancer

PROTAC SGK3 degrader-1 (SGK3-PROTAC1), a chemical probe, is a von Hippel-Lindau ligand-based SKG3 PROTAC composed of a PEG3-C4-OBn (HY-130620) alkyl linker, an SGK3 degrader (red structure), and a VHL ligand (HY-150803, blue structure). PROTAC SGK3 degrader-1 (0.3 μM) induced 50% endogenous SGK3 degradation within 2 hours, and 80% SGK3 degradation was observed at 8 hours, accompanied by loss of phosphorylation of NDRG1 (SGK3 substrate) .
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4
4 Cited Publications
Cat. No.: HY-145411
CAS No.: 1443687-74-8
Purity:  ≥98.0%
PEG2000-C-DMG, a pegylated lipid, can be used for the preparation of Onpattro. Onpattro, a hepatically directed investigational RNAi therapeutic agent, harnesses this process to reduce the production of mutant and wild-type transthyretin by targeting the 3′ untranslated region of transthyretin mRNA .
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4
4 Cited Publications
Cat. No.: HY-Y0873I
CAS No.: 25322-68-3
Synonyms: Polyethylene glycol 6000
PEG6000 can be used as an excipient, such as Ointment base, lubricant, etc. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
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4
4 Cited Publications
Cat. No.: HY-140272
CAS No.: 1427004-19-0
Purity:  98.40%
Target:  

PROTAC Linkers

Research Areas:  

Cancer

DBCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG4-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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4
4 Cited Publications
Cat. No.: HY-100874
CAS No.: 3046395-46-1
Purity:  98.56%
Research Areas:  

Cancer

N3-PEG3-vc-PAB-MMAE is a synthesized agent-linker conjugate for ADC that incorporates the MMAE (a tubulin inhibitor ) and 3-unit PEG linker. N3-PEG3-vc-PAB-MMAE shows potent antitumor activity. N3-PEG3-vc-PAB-MMAE is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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4
4 Cited Publications
Cat. No.: HY-140739
Purity:  99.58%
DSPE-PEG2000-Maleimide sodium (purity>95%) is a phospholipid-PEG conjugate. DSPE-PEG2000-Maleimide utilizes the amphiphilicity of DSPE to insert into the lipid bilayer of liposomes or nanoparticles. DSPE-PEG2000-Maleimide covalently couples to the sulfhydryl (-SH) of ligands (such as antibodies, peptides, or proteins) via thiol-maleimide click chemistry, giving the particles targeting capabilities. DSPE-PEG2000-Maleimide sodium (purity>95%) can be used in the researches of breast cancer, lymphoma, and inherited retinal degeneration .
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4
4 Cited Publications
Cat. No.: HY-140740
Purity:  99.48%
DSPE-PEG5000-Maleimide, is a linker lipid containing DSPE phospholipid and Maleimide. DSPE-PEG-Maleimide is used in the synthesis of liposomes, including HELDC liposomes, sterically stabilized liposomes, and immunoliposomes .
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4
4 Cited Publications
Cat. No.: HY-144004
CAS No.: 474922-22-0
Purity:  ≥95.0%
Synonyms: DSPE-peg2000 Maleimide ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)-2000] ammonium
DSPE-PEG-Maleimide has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-Maleimide extends blood circulation time and higher stability for encapsulated agents .
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3
3 Cited Publications
Cat. No.: HY-126403
CAS No.: 61788-85-0
Synonyms: peg-40 hydrogenated castor oil; Macrogolglycerol hydroxystearate; Castor oil, hydrogenated, polyethoxylated
Ethoxylated hydrogenated castor oil (PEG-40 hydrogenated castor oil) is a combination of synthetic polyethylene glycol (PEG) with natural castor oil. Ethoxylated hydrogenated castor oil can be used to emulsify and solubilize oil-in-water (o/w) emulsions. Ethoxylated hydrogenated castor oil can be used as a cosolvent in vivo .
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3
3 Cited Publications
Cat. No.: HY-Y0873H
CAS No.: 25322-68-3
Synonyms: Polyethylene glycol 4000
PEG4000 can be used as an excipient, such as Ointment base, lubricant, etc. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
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3
3 Cited Publications
Cat. No.: HY-W441014
DSPE-PEG2000-NHS is a PEG-modified phospholipid derivative that can be used to prepare liposomes. DSPE-PEG2000-NHS is commonly employed as a linker molecule for the surface modification of liposomes to confer targeting capabilities. DSPE-PEG2000-NHS can be used in the study of drug delivery .
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3
3 Cited Publications
Cat. No.: HY-140889
CAS No.: 459426-22-3
Purity:  99.56%
Target:  

PROTAC Linkers

Research Areas:  

Cancer

Biotin-PEG4-NHS ester is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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3
3 Cited Publications
Cat. No.: HY-111012
CAS No.: 2754384-60-4
Purity:  99.60%
Research Areas:  

Cancer

DBCO-(PEG)3-VC-PAB-MMAE is a agent-linker conjugate for ADC. DBCO-(PEG)3-VC-PAB-MMAE is made by Monomethyl auristatin E (HY-15162) conjugats to DBCO-(PEG)3-vc-PAB linker. DBCO-(PEG)3-VC-PAB-MMAE can be used for the research of cancer . DBCO-(PEG)3-VC-PAB-MMAE is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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