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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
18 Results for "
peptide deformylase
" in MedChemExpress (MCE) Product Catalog:
Products (18)
18 Results for "peptide deformylase" in MCE Product Catalog:
7
Target:
Synonyms: GSK 1322322
Lanopepden (GSK 1322322) is a peptide deformylase (PDF) inhibitor. Lanopepden exerts antibacterial activity by inhibiting the activity of PDF and preventing the correct synthesis of bacterial proteins. Lanopepden can be used for the research of acute bacterial skin and skin structure infections .
Cat. No.: HY-102008
CAS No.: 478913-91-6
Synonyms: NVP-PDF 713; VIC-104959
Target:
Research Areas:
LBM-415 (NVP-PDF 713) is a peptide deformylase (PDF) inhibitor that exhibits inhibitory activity against various antimicrobial-resistant gram-positive cocci, with a MIC90 range of 0.12-8 µg/ml. Additionally, inhibiting efflux pump activity can enhance bacterial sensitivity to LBM415, thereby improving its antibacterial efficacy .
Cat. No.: HY-102009
CAS No.: 325795-25-3
BB-83698 is a peptide deformylase (PDF) inhibitor. BB-83698 exhibits potent in vitro activity against Streptococcus pneumoniae, with a minimum inhibitory concentration (MIC) range of 0.06-0.25μg/mL. BB-83698 elevates the survival rate of mice regardless of whether the infecting strain carries resistance mechanisms. BB-83698 can be used for the study of diseases related to drug-resistant Streptococcus pneumoniae infections .
Cat. No.: HY-114900
CAS No.: 235784-88-0
Target:
BB-3497 is a potent, orally active and selective peptide deformylase (PDF) inhibitor. BB-3497 is highly selective for PDF (IC50 = 7 nM for E. coli PDF.Ni) over the other mammalian metalloenzymes (MMP-1/2/3/7 and enkephalinase). BB-3497 exhibits potent activity against gram-positive bacteria and some gram-negative pathogens. BB-3497 protects mice from infection in systemic models of Staphylococeus aureus. BB-3497 can be used for anti-bacterial infection research .
Cat. No.: HY-121610
CAS No.: 342785-41-5
FR-202306 is a compound with antibacterial and peptide deformylase inhibitory activities, isolated from microorganisms, which has an inhibitory effect on the peptide deformylase of Staphylococcus aureus and also has antibacterial activity.
Cat. No.: HY-148372
CAS No.: 111150-07-3
Target:
Research Areas:
For-Met-Leu-pNA is an N-formylated peptide substrate that can be used in the deformylase assays .
Cat. No.: HY-122097
CAS No.: 774551-07-4
Target:
Research Areas:
M7594_0037 is a potent inhibitor of human peptide deformylase (HsPDF) that has anti-tumor activity .
Cat. No.: HY-168853
CAS No.: 3036109-97-1
Antibacterial agent 261 (compound 43) is a potent inhibitor of peptidomimetic peptide deformylase (PDF), with IC50 of 2.5 and 10.6 nM for S. aureus and E. coli, respectively .
Cat. No.: HY-119728
CAS No.: 197316-54-4
Category:
Target:
Cat. No.: HY-113952R
CAS No.: 13434-13-4
Synonyms: (-)-Actinonin (Standard)
Category:
Cat. No.: HY-181674
Target:
Research Areas:
ZHO-197 is a dual bacterial peptide deformylase and methionine aminopeptidase inhibitor with antibacterial activity. ZHO-197 exhibits an Escherichia coli peptide deformylase IC50 of 0.021 μM and a human peptide deformylase IC50 of 3.289 μM. ZHO-197 displays broad-spectrum antibacterial activity against gram-positive and gram-negative bacterial strains. ZHO-197 can be used for the research of bacterial infection .
Cat. No.: HY-182256
CAS No.: 1441390-28-8
Synonyms: GSK1322322 camsylate
Target:
Research Areas:
Lanopepden camsylate (GSK1322322 camsylate) is a high-affinity bacterial peptide deformylase inhibitor. Lanopepden camsylate is applicable to research related to bacterial infections .
Cat. No.: HY-187554
CAS No.: 1091682-50-6
Target:
Research Areas:
IDP-73152 is an orally active bacterial Peptide deformylase inhibitor and Antibiotic. IDP-73152 exhibits activity against Gram-positive bacteria. IDP-73152 can be used in the research of infections caused by Streptococcus pneumoniae, Enterococcus faecium and Staphylococcus aureus .
Cat. No.: HY-187554A
CAS No.: 1936442-71-5
Target:
Research Areas:
IDP-73152 mesylate is an orally active bacterial Peptide deformylase inhibitor and Antibiotic. IDP-73152 mesylate exhibits activity against Gram-positive bacteria. IDP-73152 mesylate can be used in the research of infections caused by Streptococcus pneumoniae, Enterococcus faecium and Staphylococcus aureus .
Cat. No.: HY-P703505
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: UTP25; MGC29875; Prev. C1orf107; UTP25, Small Subunit Processor Component; Prev. DIEXF; Digestive-Organ Expansion Factor Homolog; UTP25 Small Subunit Processor Component; Digestive Organ Expansion Factor Homolog; DEF; Chromosome 1 Open Reading Frame 107;
Species:
Staphylococcus aureus
Source:
E. coli
Cat. No.: HY-P71767
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: UTP25; MGC29875; Prev. C1orf107; UTP25, Small Subunit Processor Component; Prev. DIEXF; Digestive-Organ Expansion Factor Homolog; UTP25 Small Subunit Processor Component; Digestive Organ Expansion Factor Homolog; DEF; Chromosome 1 Open Reading Frame 107;
Species:
Staphylococcus aureus
Source:
P. pastoris
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
