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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
106 Results for "
primary amino group
" in MedChemExpress (MCE) Product Catalog:
Products (106)
106 Results for "primary amino group" in MCE Product Catalog:
9
9 Publications Verification
Synonyms: HOSu; 1-Hydroxy-2,5-pyrrolidinedione
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1 Cited Publications
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DOTA-NHS-ester is a bifunctional reagent containing a DOTA chelating group and an NHS ester. DOTA-NHS-ester can be conjugated to proteins/antibodies/HSA via primary amino groups for radiolabeling with radiometals, and when combined with 16-amino-1-hexadecanethiol hydrochloride, it enables the construction of self-assembled monolayers on gold surfaces for lectin microarrays. DOTA-NHS-ester can be used to prepare DOTA-HSA-Z (HER2:342) imaging probes, as well as to construct Trop2-targeted radiotherapeutic and diagnostic probes for pancreatic cancer .
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1 Cited Publications
Cat. No.: HY-128890B
Purity: 95.00%
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DOTA-NHS-ester TFA is a bifunctional reagent containing a DOTA chelating group and an NHS ester. DOTA-NHS-ester TFA can be conjugated to proteins/antibodies/HSA via primary amino groups for radiolabeling with radiometals, and when combined with 16-amino-1-hexadecanethiol hydrochloride, it enables the construction of self-assembled monolayers on gold surfaces for lectin microarrays. DOTA-NHS-ester TFA can be used to prepare DOTA-HSA-Z (HER2:342) imaging probes, as well as to construct Trop2-targeted radiotherapeutic and diagnostic probes for pancreatic cancer .
Cat. No.: HY-79647
CAS No.: 82911-69-1
Synonyms: N-(Fmoc-oxy)succinimide
Synonyms: mPEG5000-SC; mPEG5000-Succinimidyl ester
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m-PEG5000-NHS ester (mPEG5000-SC; mPEG5000-Succinimidyl ester) is a pegylation reagent that targets the primary amino groups of branched polyethyleneimine on gold nanoparticles. m-PEG1000-NHS ester covalently links its PEG moiety to target amino groups via amine-mediated coupling chemistry. m-PEG1000-NHS ester helps improve the biocompatibility of modified gold nanoparticles used as CT contrast agents and prolongs their blood circulation time.
Synonyms: mPEG10000-NH2
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mPEG10000-amine (mPEG10000-NH2) is a monofunctional polyethylene glycol derivative-a linear PEG capped with a methoxy group at one end and a primary amino group at the other-commonly used as a hydrophilic linker in bioconjugation.
Cat. No.: HY-D1085
CAS No.: 216309-02-3
Cat. No.: HY-W012001
CAS No.: 60142-89-4
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Boc-7-Aminoheptanoic acid can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. Boc-7-Aminoheptanoic acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
Cat. No.: HY-W002041
CAS No.: 13325-10-5
Synonyms: 4-amino-1-butanol
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4-Aminobutan-1-ol (4-Amino-1-butanol) is a linear γ-amino alcohol bearing both a primary amino group and a primary hydroxyl group, which serves as a starting material for the synthesis of pyridine-based Schiff bases. As an important intermediate, 4-Aminobutan-1-ol can be used in the synthesis of GABA derivatives, chiral ligands and other active compounds .
Cat. No.: HY-W250124
CAS No.: 63231-63-0
Synonyms: RNA (yeast)
Synonyms: mPEG10000-SC; mPEG10000-Succinimidyl ester
Cat. No.: HY-W041856
CAS No.: 30100-16-4
Synonyms: Boc-8-aminooctanoic acid
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N-Boc-8-amino-octanoic acid (Boc-8-aminooctanoic acid) can be used as a PROTAC linker in the synthesis of PROTACs. N-Boc-8-amino-octanoic acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
Cat. No.: HY-W105744
CAS No.: 13108-19-5
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10-Aminodecanoic acid is an alkane chain with terminal carboxlic acid and amine groups. 10-Aminodecanoic acid can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. The amino group (NH2) is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups of activated NHS ester to form a stable amide bond.
Synonyms: mPEG20000-SC; mPEG20000-Succinimidyl ester
Cat. No.: HY-W1048525
Synonyms: 8-Arm PEG5000-Amine
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8-Arm PEG5000-NH2 (8-Arm PEG5000-Amine) is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
Cat. No.: HY-W142618
CAS No.: 13265-84-4
Cat. No.: HY-155908
CAS No.: 474922-26-4
Synonyms: DSPE-PEG10000-NH2 ammonium
DSPE-PEG10000-Amine ammonium (DSPE-PEG10000-NH2 ammonium) is a PEGylated distearoylphosphatidylethanolamine lipid with a terminal primary amino group. DSPE-PEG10000-Amine ammonium serves as a liposome component, and its surface bears reactive primary amino groups that enable covalent conjugation via the formation of bis-aryl hydrazone bonds .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
