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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
procaspases 3
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "procaspases 3" in MCE Product Catalog:
9
9 Publications Verification
Synonyms: RGDS peptide; Fibronectin tetrapeptide
Target:
Research Areas:
9
9 Publications Verification
Cat. No.: HY-P1740
CAS No.: 114681-65-1
Research Areas:
9
9 Publications Verification
Cat. No.: HY-P1740A
Research Areas:
7
Procaspase-3/6 activator 1 (compound 1541) is a highly specific and robust activator of executioner procaspases-3 and -6, with EC50 values of 2.4 ± 0.2 and 2.8 ± 0.3 μM, respectively. Procaspase-3/6 activator 1 does not activate procaspases-1 or -7 .
Cat. No.: HY-W748509
CAS No.: 88660-10-0
Research Areas:
2-Chlorohexadecanoic acid, an inflammatory lipid mediator, interferes with protein palmitoylation,induces ER-stress markers, reduced the ER ATP content, and activates transcription and secretion of IL-6 as well as IL-8.2-Chlorohexadecanoic acid disrupts the mitochondrial membrane potential and induces procaspase-3 and PARP cleavage.2-Chlorohexadecanoic acid can across blood-brain barrier (BBB) and compromises ER- and mitochondrial functions in the human brain endothelial cell line hCMEC/D3 .
Cat. No.: HY-13523S
CAS No.: 1287241-26-2
Synonyms: Procaspase activating compound 1-d8
Cat. No.: HY-N5033
CAS No.: 1029017-75-1
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17-Hydroxy sprengerinin C (compound 10) is a glycoside compound isolated from rhizomes of Polygonatum sibiricum. 17-Hydroxy sprengerinin C possesses stronger anticancer activities. 17-Hydroxy sprengerinin C reduces the expression of Blc-2 and pro-caspase3 and increases the production of Bax .
Cat. No.: HY-12290A
Synonyms: RGDS peptide TFA; Fibronectin tetrapeptide TFA
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Cat. No.: HY-12290R
CAS No.: 91037-65-9
Synonyms: RGDS peptide (Standard); Fibronectin tetrapeptide (Standard)
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Cat. No.: HY-179699
Procaspase-3 activator 1 is a potent procaspase-3 activator. Procaspase-3 activator directly activates procaspase-3 through zinc chelation, thereby inducing apoptosis and inhibiting cancer cell proliferation. Procaspase-3 activator 1 can be used for the research of non-small cell lung cancer (NSCLC) and melanoma .
Cat. No.: HY-10132
CAS No.: 1170689-68-5
CASP3 activator 1 is an activator of executioner procaspases 3, 6 and 7. CASP3 activator 1 can be used for the research of cancer, neoplastic diseases .
Cat. No.: HY-181168
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Lb54 is a caspase-3 and caspase-7 activator with an EC50 of 660.9 nM for human procaspase-3. Lb54 activates caspase-3/7, which cleaves Gasdermin D (GSDMD) at aspartic acid residue 87 to generate a p10 fragment, preventing formation of the pore-forming p30 fragment of GSDMD. Lb54 suppresses GSDMD-mediated pyroptosis through caspase-3/7 activation, thereby attenuating inflammatory responses and conferring protection against sepsis. Lb54 alleviates acute lung injury, and inhibited systemic inflammation by restraining the maturation of monocyte-derived dendritic cells. Lb54 can be used for the research of sepsis .
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
