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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
44 Results for "
quality control
" in MedChemExpress (MCE) Product Catalog:
Products (44)
44 Results for "quality control" in MCE Product Catalog:
1
Category:
Target:
1
1 Cited Publications
Synonyms: CK, CPK, Creatine Phosphokinase
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Creatine Kinase (CPK/CK), Bovine Heart (CK) is a creatine kinase derived from bovine heart. Creatine Kinase (CPK/CK), Bovine Heart catalyzes the reversible phosphate transfer reaction between phosphocreatine and ADP, and is widely used in myocardial energy metabolism research and quality control of clinical biochemical tests .
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1 Cited Publications
Cat. No.: HY-N7026
CAS No.: 1807732-38-2
Category:
Celosia argentea Linn. Triterpenes Terpenoids Metabolic Disease Amaranthaceae Plants Disease Research Fields
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Duostatin 5 is a ADC Cytotoxin designed based on MMAF (HY-15579) and can be used to synthesize ADCs. The preparation of Duostatin 5 has the advantages of fewer synthetic steps, simple operation, less difficulty in quality control, and more stable chemical synthesis process. Duostatin 5 can be linked to the antibody targeting 5T4 (ZV05) by cross-linking with interchain cysteines through a disubstituted C-Lock linker. Duostatin 5 is a click chemistry reagent. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-driven alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups[1][2].
Cat. No.: HY-Z8754
CAS No.: 129212-35-7
Synonyms: Tacrolimus EP impurity D; 8-epi-Tacrolimus
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Tacrolimus 8-epimer (Tacrolimus EP impurity D) is the C-8 epimer and degradation impurity of Tacrolimus (HY-13756). Tacrolimus 8-epimer forms via base-catalyzed epimerization of Tacrolimus, and also generates under iodine-catalyzed free radical conditions. Tacrolimus 8-epimer is mainly used as a reference substance for impurity analysis, pharmaceutical quality control and stability-related studies of Tacrolimus .
Cat. No.: HY-W059210
CAS No.: 952518-97-7
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Ruxolitinib impurity-1 is a pyrrolopyrimidine derivative and also an impurity of Ruxolitinib (HY-50856). Ruxolitinib serves as a synthetic intermediate for TDM-180967, a dual JAK1/Tyk2 inhibitor, and can also be used as an impurity reference standard for drug quality control .
Cat. No.: HY-177569
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NVS1.1 is an orally active, blood-brain barrier-penetrant eRF1 degrader. NVS1.1 induces ubiquitination of eRF1 at Lys279, mediates proteasomal degradation via the E3 ubiquitin ligases RNF14 and RNF25 as well as the translational stress sensor GCN1, traps eRF1 at the ribosomal A-site, inhibits translation termination and triggers ribosome collision. As a readthrough enhancer, NVS1.1 enables near-cognate tRNA incorporation at premature termination codons by reducing intracellular eRF1 levels. NVS1.1 activates ribosome-associated quality control pathways via ribosome collision, including ubiquitination of small subunit ribosomal proteins. NVS1.1 restores functional full-length CFTR and IDUA proteins and reduces glycosaminoglycan accumulation in relevant models. NVS1.1 can be used in the research of cystic fibrosis and Hurler syndrome (mucopolysaccharidosis type I, MPS I) .
Cat. No.: HY-177757
CAS No.: 1831092-94-4
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NVS2.1 is a potent, orally active and brain-penetrant readthrough promoter. NVS2.1 triggers the degradation of eRF1 by activating the ribosome-related quality control pathways (involving GCN1, RNF14, and RNF25), thereby facilitating the reading through of premature termination codons. NVS2.1 can be used for the research of genetic diseases caused by nonsense mutations .
Cat. No.: HY-N0624
CAS No.: 146501-37-3
Category:
Flavonols Flavonoids Papilionaceae Phenols Polyphenols Plants Disease Research Fields Astragalus complanatus Cancer
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Cat. No.: HY-I0165
CAS No.: 1267610-26-3
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Apixaban impurity 11 is an impurity of Apixaban (HY-50667). Apixaban impurity 11 can be used for impurity identification, analytical method development and quality control of Apixaban.
Cat. No.: HY-P10416
Synonyms: Q14 peptide
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Cat. No.: HY-P4890
CAS No.: 1158181-62-4
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RXFP Receptor Reactive Oxygen Species (ROS) Pyroptosis Caspase Interleukin Related TGF-beta/Smad AMPK Apoptosis
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Cat. No.: HY-118615
CAS No.: 676495-11-7
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LY2048978 is a non-selective opioid receptor antagonist with Ki of 0.287, 0.471 and 1.05 nM for human mu, kappa and delta opioid receptors in vitro, respectively. LY2048978 can be used in the research of major depressive disorder and alcohol use disorder .
Cat. No.: HY-W488109
CAS No.: 97-16-5
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Genite is a highly effective pesticide with strong insecticidal activity. Genite can effectively control the number of various pests and is widely used in agricultural production. The use of Genite can significantly increase the yield and quality of crops.
Cat. No.: HY-W774918
CAS No.: 153197-14-9
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Oxaziclomefone is a broad-spectrum pesticide with fungal activity. Oxaziclomefone effectively controls a variety of crop diseases and has significant effects against plant pathogenic fungi. Oxaziclomefone is widely used in agriculture to protect crops from diseases and improve crop yield and quality.
Cat. No.: HY-112101R
CAS No.: 158474-72-7
Synonyms: n-Propyl dihydrojasmonate (Standard)
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Oxaziclomefone (Standard) is the analytical standard of Oxaziclomefone. This product is intended for research and analytical applications. Oxaziclomefone is a broad-spectrum pesticide with fungal activity. Oxaziclomefone effectively controls a variety of crop diseases and has significant effects against plant pathogenic fungi. Oxaziclomefone is widely used in agriculture to protect crops from diseases and improve crop yield and quality.
Cat. No.: HY-W774918R
CAS No.: 153197-14-9
Target:
Oxaziclomefone (Standard) is the analytical standard of Oxaziclomefone. This product is intended for research and analytical applications. Oxaziclomefone is a broad-spectrum pesticide with fungal activity. Oxaziclomefone effectively controls a variety of crop diseases and has significant effects against plant pathogenic fungi. Oxaziclomefone is widely used in agriculture to protect crops from diseases and improve crop yield and quality.
Cat. No.: HY-P4890A
Target:
RXFP Receptor Reactive Oxygen Species (ROS) Pyroptosis Caspase Interleukin Related TGF-beta/Smad AMPK Apoptosis
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Cat. No.: HY-181764
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LZL50 is an orally effective human caseinolytic protease P (hClpP) activator with an EC50 of 0.29 μM. LZL50 activates hClpP, a serine protease that mediates mitochondrial quality control by degrading damaged or misfolded mitochondrial proteins. LZL50 exhibits antitumor activity in a breast cancer xenograft mouse model. LZL50 can be used in research related to breast cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
