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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
67 Results for "
self-assembly
" in MedChemExpress (MCE) Product Catalog:
Products (67)
67 Results for "self-assembly" in MCE Product Catalog:
23
23 Publications Verification
Referencia número: HY-W099571
No. CAS: 4485-12-5
Synonyms: Stearic acid lithium; Lithium octadecanoate
Áreas de investigación:
Lithium stearate (Stearic acid (lithium)) is a compound that forms vesicles in reaction with silver nitrate, thereby changing the reaction kinetics of the nucleation and self-assembly process of silver stearate. It has the activity that even in the presence of excess silver nitrate, only about 80% can be converted into silver stearate and the residual lithium stearate will inhibit the growth process of silver stearate crystals, thereby producing silver stearate crystals that are much smaller than those obtained from sodium stearate, providing an opportunity to further control the self-assembly and crystal growth of silver stearate.
2
Target:
Áreas de investigación:
Protriptyline hydrochloride is a potent tricyclic antidepressant (TCA). Protriptyline hydrochloride inhibits AChE activity with an IC50 value of 0.06 mM and inhibits Aβ self-assembly. Protriptyline hydrochloride can be used for the study of depression and Alzheimers disease .
2
Category:
Alkaloids Plant Catharanthus roseus (L.) G. Don Extract Disease Research Fields Cancer Indole Alkaloids Apocynaceae Extract
Target:
Synonyms: N-FMOC-leucine; NPC 15199; NSC 334290
Target:
Áreas de investigación:
Fmoc-Leucine (N-FMOC-leucine) is an anti-inflammatory agent that not only promotes extracellular Ca 2+ influx but also facilitates intracellular Ca 2+ release. Fmoc-Leucine is a selective ligand for PPARγ (Ki = 15 μM), exhibiting insulin-sensitizing effects but with weak fatogenic activity. Fmoc-Leucine exhibits unique self-assembly properties and can form transient gels, stable gels, or crystals/2D sheets through different pathways. Fmoc-Leucine can be used in the research of diabetes, colitis, and bladder cancer .
Referencia número: HY-P1449
No. CAS: 187794-49-6
Target:
Áreas de investigación:
Referencia número: HY-P4808
No. CAS: 329897-62-3
Áreas de investigación:
Target:
Áreas de investigación:
Soya Lecithin is a phospholipid mixture that can be used as a drug delivery vehicle and is a pharmaceutical excipient. Soya Lecithin can form a lipid bilayer structure through self-assembly, and its binding properties are amphiphilic (hydrophilic head and hydrophobic tail), encapsulating hydrophobic drugs. Soya Lecithin forms stable nanoliposomes or microemulsions, improves the solubility and cellular uptake efficiency of poorly soluble drugs (such as Curcumin (HY-N0005)), and exerts activities such as enhancing drug delivery and regulating cell proliferation .
Target:
ADH-6 TFA is a tripyridylamide compound. ADH-6 abrogates self-assembly of the aggregation-nucleating subdomain of mutant p53 DBD. ADH-6 TFA targets and dissociates mutant p53 aggregates in human cancer cells, which restores p53's transcriptional activity, leading to cell cycle arrest and apoptosis. ADH-6 TFA has the potential for the research of cancer diseases .
Referencia número: HY-P4637
No. CAS: 22951-98-0
Synonyms: H-Ile-Phe-OH
Referencia número: HY-P4808A
Áreas de investigación:
Referencia número: HY-W440697
Target:
Áreas de investigación:
Cholesterol-PEG1000-NHS is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG1000-NHS can be used in drug delivery research .
Referencia número: HY-158189
No. CAS: 3030629-73-0
Áreas de investigación:
TPP-Ce6 is a mitochondria-targeted photosensitizer formed by the ester bond conjugation of chlorophyll e6 (Ce6) with triphenylphosphine (TPP). Under light irradiation or ultrasound exposure, TPP-Ce6 generates reactive oxygen species, induces cell apoptosis, and triggers immunogenic cell death. TPP-Ce6 can serve as a component of carrier-free co-delivery systems, undergo enzyme-induced self-assembly within tumors, and modulate tumor hypoxia. TPP-Ce6 is applicable to research on breast cancer and glioblastoma .
Referencia número: HY-P5681
Target:
Áreas de investigación:
Referencia número: HY-P1449A
No. CAS: 2450273-39-7
Target:
Áreas de investigación:
Áreas de investigación:
Dodecylamine (Laurylamine) is a saturated aliphatic amine with cytotoxicity. Dodecylamine can act as a ligand for the extracellular recognition segment CD36149‑168 of the human CD36 receptor, with a human EC50 of 19 μM. After conjugation with BSA, Dodecylamine can increase hydrophobicity/amphiphilicity and promote self-assembly into cationic nanoparticles. Dodecylamine can be used in research related to CD36 receptor ligand recognition and nanoparticle synthesis .
Referencia número: HY-145785
No. CAS: 2227429-65-2
ADH-6 is a tripyridylamide compound. ADH-6 abrogates self-assembly of the aggregation-nucleating subdomain of mutant p53 DBD. ADH-6 targets and dissociates mutant p53 aggregates in human cancer cells, which restores p53's transcriptional activity, leading to cell cycle arrest and apoptosis. ADH-6 has the potential for the research of cancer diseases[1].
Referencia número: HY-178106
Target:
Áreas de investigación:
SCN2 is a esterase-responsive prodrug-based amphiphile composed of SN38 (HY-13704) and di-(triazole-[12]aneN3, N) moiety through a 7‑carbon alkyl chains. SCN2 has excellent self-assembly and reversible siRNA condensation capabilities as well as anti-proliferation activity against cancer cells. SCN2 can be used for synthesis of nanoparticles for drug delivery of lung cancer .
Target:
Áreas de investigación:
Aβ42 agonist-2 (compound 7b) is a small molecule compound that can promote Aβ42 aggregation. Aβ42 agonist-2 can interact with Aβ42 oligomers and pentamers to promote nontoxic aggregate self-assembly and rapid fibril formation. Aβ42 agonist-2 prevents Aβ42-induced cytotoxicity in HT22 hippocampal neuronal cells .
Referencia número: HY-P10701
No. CAS: 581799-39-5
Target:
Áreas de investigación:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
