20 Results for "

split intein

" in MedChemExpress (MCE) Product Catalog:
Products (20)

20 Results for "split intein" in MCE Product Catalog:

30
30 Publications Verification
Cat. No.: HY-Y1883
CAS No.: 9002-93-1
Domaines de recherche:  

Infection Cancer

Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant is a non-denaturing detergent that solubilizes lipid membranes. Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant is commonly used in laboratories and is applied to vaccines at different stages of the manufacturing process. Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant is listed as an excipient in certain vaccines including split virus influenza vaccines. Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant is a nonionic surfactant. Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant induces Apoptosis in prostate and colon cancer cell lines and reduces the infectivity of classic enveloped viruses such as WNV .
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30
30 Publications Verification
Cat. No.: HY-Y1883A
CAS No.: 9002-93-1
Domaines de recherche:  

Infection Cancer

Polyethylene glycol mono(4-tert-octylphenyl) ether is a non-denaturing detergent that solubilizes lipid membranes. Polyethylene glycol mono(4-tert-octylphenyl) ether is commonly used in laboratories and is applied to vaccines at different stages of the manufacturing process. Polyethylene glycol mono(4-tert-octylphenyl) ether is listed as an excipient in certain vaccines including split virus influenza vaccines. Polyethylene glycol mono(4-tert-octylphenyl) ether is a nonionic surfactant. Polyethylene glycol mono(4-tert-octylphenyl) ether induces Apoptosis in prostate and colon cancer cell lines and reduces the infectivity of classic enveloped viruses such as WNV .
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1
1 Cited Publications
Cat. No.: HY-P80155
Synonyms: bHLHb39 antibody; C-HAIRY1 antibody; Class B basic helix-loop-helix protein 39 antibody; FLJ20408 antibody; Hairy and enhancer of split 1 antibody; Hairy homolog (Drosophila) antibody; Hairy homolog antibody; Hairy like antibody; Hairy, Drosophila, homolog of antibody; Hairy-like protein antibody; HAIRY1 antibody; HES-1 antibody; HES1_HUMAN antibody; HHL antibody; HL antibody; HRY antibody; MGC129109 antibody; OTTHUMP00000209031 antibody; RHL antibody; Transcription factor HES-1 antibody

Host:  

Rabbit

Application:  

WB, ICC/IF, IHC-P, FC

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-112452
CAS No.: 326914-10-7
Pureté:  99.06%
Domaines de recherche:  

Cancer

SU11652 is a potent receptor tyrosine kinase (RTK) inhibitor. SU11652 also inhibits several members of the split kinase family of RTKs, including VEGFR, FGFR, PDGFR, and Kit. SU11652 can be uesd for spontaneous cancers expressing Kit mutations research .
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Cat. No.: HY-P11329
CAS No.: 862973-56-6
Target:  

Fluorescent Dye

Domaines de recherche:  

Others

GFP11 is a protein fusion tag consisting of 16 amino acids. When GFP11 and GFP1-10 are sufficiently close in physical space, they undergo spontaneous, irreversible complementation to reassemble into an intact, functional GFP protein that emits green fluorescence. GFP11 can be used to form a split GFP system for high-throughput biotechnology and flow cytometry applications .
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Cat. No.: HY-N3393
CAS No.: 221289-31-2
Lethedioside A is a Enhancer of split 1 (Hes1) inhibitor with an IC50 of 9.5 μM. Lethedioside A inhibits Hes1 dimer formation. Lethedioside A exhibits weak inhibition of TCF4/β-catenin complex formation. Lethedioside A inhibits nitric oxide production by activated immune cells .
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Cat. No.: HY-107950
CAS No.: 8013-17-0
Domaines de recherche:  

Others

Invert sugar is a mixture of dextrose and levulose. Invert sugar is formed when sucrose is split in two by an enzyme or acid. Invert sugar can be used as a sweetener .
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Cat. No.: HY-157797
CAS No.: 2376127-86-3
Target:  

Topoisomerase

Domaines de recherche:  

Cancer

SN-38-CM2 is a split esterase, and shows >95% conversion to SN-38 within 5 min in vitro. SN-38-CM2 induces protein-protein interactions (PPI)-dependent esterase to mediate cell death in MDA-MB-231 cells .
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Cat. No.: HY-181101
CAS No.: 3097563-43-1
Target:  

Fungal

Domaines de recherche:  

Infection

Antifungal agent 151 is a Prp8 intein inhibitor that inhibits the self-splicing process of the Prp8 intein, preventing maturation of the Prp8 protein. Antifungal agent 151 exerts in vitro antifungal activity against Cryptococcus neoformans and Cryptococcus gattii. Antifungal agent 151 can be used for the research of cryptococcus pneumonia .
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Cat. No.: HY-P76675
Pureté:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TLE3; Enhancer Of split Groucho-Like Protein 3; TLE Family Member 3, Transcriptional Corepressor; Transducin Like Enhancer Of split 3; ESG3; Transducin-Like Enhancer Protein 3; HsT18976; Transducin-Like Enhancer Of split 3, Homolog Of Drosophila E(Sp1); K
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P81704
Synonyms: BHLHB38; HES5; Transcription factor HES-5; Class B basic helix-loop-helix protein 38; Hairy and enhancer of split 5; bHLHb38

Host:  

Rabbit

Application:  

WB, IHC-P, IP

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P86085
Synonyms: BHLHB39; HL; HRY; HES1; Transcription factor HES-1; Class B basic helix-loop-helix protein 39; Hairy and enhancer of split 1; Hairy homolog; Hairy-like protein; bHLHb39; hHL

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IP, ELISA

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P83037
Synonyms: DGCR1; HIR; TUPLE1; HIRA; Protein HIRA; TUP1-like enhancer of split protein 1

Host:  

Rabbit

Application:  

WB, ICC/IF, FC, IP

Reactivity:  

Human

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Cat. No.: HY-P88465
Synonyms: TLE2; Transducin-like enhancer protein 2; Enhancer of split groucho-like protein 2

Host:  

Mouse

Application:  

IHC-P, ICC/IF, FC

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P88465A
Synonyms: TLE2; Transducin-like enhancer protein 2; Enhancer of split groucho-like protein 2

Host:  

Mouse

Application:  

IHC-P, ICC/IF, FC

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P82546
Synonyms: Transducin-like enhancer protein 1; E(Sp1) homolog; Enhancer of split groucho-like protein 1; ESG1; TLE1

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P88608
Synonyms: BHLHB3; DEC2; SHARP1; BHLHE41; Class E basic helix-loop-helix protein 41; bHLHe41; Class B basic helix-loop-helix protein 3; Differentially expressed in chondrocytes protein 2; Enhancer-of-split and hairy-related protein 1; bHLHb3; hDEC2; SHARP-1

Host:  

Mouse

Application:  

IHC-P

Reactivity:  

Human

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Cat. No.: HY-P88608A
Synonyms: BHLHB3; DEC2; SHARP1; BHLHE41; Class E basic helix-loop-helix protein 41; bHLHe41; Class B basic helix-loop-helix protein 3; Differentially expressed in chondrocytes protein 2; Enhancer-of-split and hairy-related protein 1; bHLHb3; hDEC2; SHARP-1

Host:  

Mouse

Application:  

IHC-P

Reactivity:  

Human

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Cat. No.: HY-P87071
Synonyms: BHLHB2; DEC1; SHARP2; STRA13; BHLHE40; Class E basic helix-loop-helix protein 40; bHLHe40; Class B basic helix-loop-helix protein 2; Differentially expressed in chondrocytes protein 1; Enhancer-of-split and hairy-related protein 2; Stimulated by retinoic acid gene 13 protein; bHLHb2; SHARP-2

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF

Reactivity:  

Human

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Cat. No.: HY-LD002
100 billion compounds

The discovery of hit molecule is a cornerstone of drug development. Among the diverse tools available, DNA-encoded libraries have emerged a revolutionary platform for high-throughput screening. Compared with traditional HTS, DEL features shorter screening processes, lower costs, simpler assays, and larger library capacities.

DEL Construction utilizes split-and-pool synthesis, a combinatorial chemistry approach that involves iterative splitting, reaction, and pooling. This strategy enables rapid, exponential assembly of fragments in minimal steps without the need for individual compound synthesis andassoicicated isolation or purification steps, thus greatly reducing overall costs. The technology enables simultaneous affinity screeningof massive compound collections to target proteins in a single step. By coupling chemical structures with unique DNA barcodes, each compound is tagged with a distinct DNA sequence for convenient tracking and decoding.DELs readily enable the construction and efficient screening of libraries containing millions to billions of compounds. As a result, DEL screening combines the dual advantages of high efficiency and low cost, making DEL a transformative technology in modern drug discovery.

The DEL kit consists of 50 independent libraries with a total scale of 100 billion compounds. It is constructed through stepwise combinatorial chemistry strategies involving 2-, 3-, and 4-round synthesis. By employing diverse scaffolds and flexible linking strategies, it encompasses various ring systems, linear frameworks, and heterocyclic structures. Screening can be achieved solely through affinity, independent of target-specific activity detection methods. This library is suitable for DEL screening against a wide range of targets.

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