Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
105 Results for "
spreading
" in MedChemExpress (MCE) Product Catalog:
Products (105)
105 Results for "spreading" in MCE Product Catalog:
67
67 Publications Verification
Synonyms: R428; BGB324
Target:
Domaines de recherche:
Bemcentinib (R428) is a selective and orally active Axl inhibitor with an IC50 of 14 nM. Bemcentinib retards cancer cell migration and invasion. Bemcentinib exhibits >100-fold selectivity for Axl versus Abl and 50- and >100-fold selectivity over TAM family kinases Mer and Tyro3, respectively, in cells. Bemcentinib blocks tumor spread and prolongs survival in models of metastatic breast cancer .
17
17 Cited Publications
Synonyms: DMP 266; EFV; L-743726
Efavirenz (DMP 266) is a potent inhibitor of the wild-type HIV-1 reverse transcriptase with a Ki of 2.93 nM and exhibits an IC95 of 1.5 nM for the inhibition of HIV-1 replicative spread in cell culture .
7
7 Cited Publications
Cat. No.: HY-P1416
CAS No.: 881188-51-8
7
7 Cited Publications
Cat. No.: HY-P1416A
4
4 Cited Publications
Cat. No.: HY-B0693
CAS No.: 66357-35-5
Target:
Domaines de recherche:
Ranitidine is a potent, selective and orally active histamine H2-receptor antagonist that inhibits gastric secretion. Ranitidine antagonizes Histamine (HY-B1204)-induced increases of the guinea-pig isolated rat atrium and Histamine-induced relaxations of the rat isolated uterine horn, with pA2 values of 7.2 and 6.95, respectively. Ranitidine inhibits breast tumor development and spread in mice .
4
4 Cited Publications
Cat. No.: HY-B0281A
CAS No.: 66357-59-3
Target:
Domaines de recherche:
Ranitidine hydrochloride is a potent, selective and orally active histamine H2-receptor antagonist that inhibits gastric secretion. Ranitidine hydrochloride antagonizes Histamine (HY-B1204)-induced increases of the guinea-pig isolated rat atrium and Histamine-induced relaxations of the rat isolated uterine horn, with pA2 values of 7.2 and 6.95, respectively. Ranitidine hydrochloride inhibits breast tumor development and spread in mice .
2
2 Cited Publications
Cat. No.: HY-P99019
CAS No.: 1655501-53-3
Synonyms: TEV-48125; LBR-101; PF-04427429; RN-307
Target:
Domaines de recherche:
2
2 Cited Publications
Cat. No.: HY-P70485
Pureté: ≥ 95%, as determined by reducing SDS-PAGE or Bis-Tris PAGE.
Synonyms: VTN; Vitronectin; VN; Serum spreading Factor; Serum-spreading Factor; Complement S-Protein; Somatomedin B; S-Protein; V75; Vitronectin (Serum spreading Factor, Somatomedin B, Complement S-Protein); Epibolin; VNT
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P3161
CAS No.: 936541-36-5
1
1 Cited Publications
Cat. No.: HY-P73484
Pureté: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: VTN; Vitronectin; VN; Serum spreading Factor; Serum-spreading Factor; Complement S-Protein; Somatomedin B; S-Protein; V75; Vitronectin (Serum spreading Factor, Somatomedin B, Complement S-Protein); Epibolin; VNT
Species:
Mouse
Source:
HEK293
Target:
Domaines de recherche:
Acetylcholinesterase, Fly head (ACHE; EC 3.1.1.7) is a cholinergic enzyme mainly found in neuromuscular junctions and cholinergic type chemical synapses used in biochemical research. Acetylcholinesterase, Fly head catalyzes the breakdown or hydrolysis of acetylcholine and some other choline esters that act as neurotransmitters into acetate and choline. Acetylcholinesterase, Fly head's main role is to terminate neuronal transmission and signaling between synapses to prevent ACh spread and activation of nearby receptors .
Cat. No.: HY-P99471
CAS No.: 2244960-75-4
Synonyms: UCB 0107
Target:
Domaines de recherche:
Cat. No.: HY-P0131A
CAS No.: 2828432-44-4
Synonyms: Laminin (925-933) TFA
Target:
Domaines de recherche:
Laminin peptide CDPGYIGSR TFA (Laminin (925-933) TFA) is a peptide fragment derived from the laminin B1 chain that binds to laminin receptors, and acts as a ligand for the laminin receptor. Laminin peptide CDPGYIGSR TFA mediates cell spreading, induces the clustering of receptors with vinculin and α-actinin, regulates the actin cytoskeleton, promotes the formation of stress fibers, and enhances epithelial cell adhesion. Laminin peptide CDPGYIGSR TFA can be used in studies related to tumor metastasis and nerve injury .
Cat. No.: HY-N2163
CAS No.: 172760-03-1
Category:
Other Monoterpenes Monophenols Terpenoids Other Diseases Phenols Plants Other Families Extract Disease Research Fields
Target:
Cat. No.: HY-P990995
CAS No.: 2690265-18-8
Synonyms: E2814
Target:
Domaines de recherche:
Synonyms: NSC 3778; O-Methylsalicylic acid; Salicylic acid methyl ether
Target:
Cat. No.: HY-P5558
CAS No.: 917760-16-8
Target:
Domaines de recherche:
Cat. No.: HY-172760
CAS No.: 3104363-32-5
CIM-834 is an orally effective inhibitor of SARS-CoV-2 membrane protein. CIM-834 can prevent the assembly of infectious virus particles without inhibiting the synthesis of viral RNA. CIM-834 can reduce the viral titer in the lungs of SCID mice infected nasally with SARS-CoV-2, block the spread of SARS-CoV-2 among Syrian hamsters, and inhibit the replication of SARS-CoV-2 (including variants) and SARS-CoV. CIM-834 can be used in related research on COVID-19 .
Cat. No.: HY-138053
CAS No.: 92989-99-6
Synonyms: Ristomycin III
Target:
Domaines de recherche:
Ristocetin A (sulfate) (Ristomycin III) is a glycopeptide antibiotic that binds to von Willebrand factor (VWF) and bacterial cell wall components. Ristocetin A (sulfate) interferes with the biosynthesis of bacterial peptidoglycan by inhibiting transpeptidation. As an inducer of platelet adhesion and aggregation, Ristocetin A (sulfate) drives conformational changes by binding to the A1 domain of VWF, thereby activating downstream signaling pathways and promoting cytoskeletal rearrangement. Ristocetin A (sulfate) not only enhances platelet adhesion and spreading on immobilized VWF, but also induces the formation of asymmetric dimers with anticooperativity between platelets and plasma VWF. Ristocetin A (sulfate) is widely used in studies related to thromboembolic diseases and bacterial infections .
Cat. No.: HY-W145493
CAS No.: 31692-85-0
Synonyms: Tetraglycol; Poly(ethylene glycol) tetrahydrofurfuryl ether
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
