76 Results for "

testis

" in MedChemExpress (MCE) Product Catalog:
Products (76)

76 Results for "testis" in MCE Product Catalog:

  • Targets Recommended:
4
4 Cited Publications
Cat. No.: HY-W583749
CAS No.: 73606-19-6
Research Areas:  

Endocrinology

6:2 Cl-PFAES is an orally effective alternative to Perfluorooctane sulfonate. 6:2 Cl-PFAES significantly inhibits the growth of zebrafish and induces reproductive toxicity. 6:2 Cl-PFAES reduces the relative weights of epididymis and testis in male BALB/c mice. 6:2 Cl-PFAES can be used in the chrome plating industry .
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3
3 Cited Publications
Cat. No.: HY-P2293
CAS No.: 39341-83-8
Target:  

Endogenous Metabolite

Research Areas:  

Endocrinology

Luteinizing hormone (human), a heterodimeric glycoprotein hormone produced by the pituitary gland (LH), plays key roles in human reproduction .
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3
3 Cited Publications
Cat. No.: HY-W011094
CAS No.: 1477-57-2
Research Areas:  

Endocrinology

Win 18446 is an orally active testes-specific enzyme ALDH1a2 inhibitor, with an IC50 of 0.3 μM. Win 18446 reversibly inhibits spermatogenesis in many species and inhibits Retinoic acid (HY-14649) biosynthesis from Retinol (HY-B1342) within the testes .
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2
2 Cited Publications
Cat. No.: HY-P701317
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Transcription factor A, mitochondrial; mtTFA; testis-specific high mobility group protein (TS-HMG); Hmgts
Species:  
Source:  
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1
1 Cited Publications
Cat. No.: HY-15357
CAS No.: 761436-81-1
Purity:  99.62%
Research Areas:  

Cancer

ALK inhibitor 1 (compound 17) is a potent pyrimidin ALK inhibitor. ALK inhibitor 1 is a potent inhibitor of testis-specific serine/threonine kinase 2 (TSSK2; IC50=31 nM) and focal adhesion kinase (FAK; IC50=2 nM) .
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1
1 Cited Publications
Cat. No.: HY-P3343A
Target:  

Estrogen Receptor/ERR

Research Areas:  

Endocrinology

hFSH-β-(33-53) TFA is a polypeptide corresponding to residues 33-53 of hFSH-β, and also a follicle-stimulating hormone (FSH) antagonist. hFSH-β-(33-53) stimulates basal estradiol synthesis in cells. hFSH-β-(33-53) TFA prolongs vaginal estrus in mice with normal estrous cycles .
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1
1 Cited Publications
Cat. No.: HY-P701316
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Transcription factor A, mitochondrial; mtTFA; testis-specific high mobility group protein (TS-HMG); Hmgts
Species:  
Source:  
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1
1 Cited Publications
Cat. No.: HY-P3343
CAS No.: 142154-55-0
Target:  

Estrogen Receptor/ERR

Research Areas:  

Endocrinology

hFSH-β-(33-53) is a polypeptide corresponding to residues 33-53 of hFSH-β, and also a follicle-stimulating hormone (FSH) antagonist. hFSH-β-(33-53) stimulates basal estradiol synthesis in cells. hFSH-β-(33-53) prolongs vaginal estrus in mice with normal estrous cycles .
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Cat. No.: HY-W017758
CAS No.: 504-63-2
1,3-Propanediol is a versatile plant-derived humectant and solvent . 1,3-Propanediol can be produced by Klebsiella pneumoniae via glycerol fermentation, with the highest yield under anaerobic conditions. 1,3-Propanediol serves as a solvent and stabilizer in film preparation processes .
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Cat. No.: HY-113306
CAS No.: 5142-22-3
Purity:  99.88%
1-Methyladenine is a gonad maturation-promoting regulator. 1-Methyladenine is produced in testes and ovarian follicle cells of starfish under the induction of gonad-stimulating substance (GSS). 1-Methyladenine promotes starfish oocyte maturation and spawning, and modifies bases that regulate DNA structure. 1-Methyladenine converts T-A base pairs in double-stranded DNA into non-disruptive T (anti)m1A (syn) Hoogsteen conformation. If this conformational base is not repaired in a timely manner, 1-Methyladenine transforms into cytotoxic DNA damage and blocks the replication process .
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Cat. No.: HY-15358
CAS No.: 761438-38-4
Purity:  99.57%
Research Areas:  

Cancer

ALK inhibitor 2 (compound 18) is a potent pyrimidin ALK inhibitor. ALK inhibitor 2 is a potent inhibitor of testis-specific serine/threonine kinase 2 (TSSK2; IC50=37 nM) and focal adhesion kinase (FAK; IC50=5 nM) .
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Cat. No.: HY-162565
CAS No.: 3086536-23-1
Target:  

STK33 CDK RET

Research Areas:  

Endocrinology

CDD-2807 is an inhibitor for serine/threonine kinase 33 (STK33) with IC50 of 9.2 nM. CDD-2807 exhibits no significant toxicity in mice and can cross the blood-testis barrier without accumulating in the brain. CDD-2807 induces a reversible contraceptive effect and has potential for the development of the male contraceptive .
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Cat. No.: HY-E70558A
Target:  

5 alpha Reductase

Research Areas:  

Endocrinology

5α-Reductase, Rat (Sprague-Dawley) Testis is the enzyme responsible for the conversion of testosterone into 5-alpha dihydrotestosterone (DHT), which is a potent androgen involved in male sexual differentiation.5α-reductase enzyme family is comprised of 3 subfamilies and 5 isoenzyme members: 5αR1, 5αR2, 5αR3, GPSN2, and GPSN2L .
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Cat. No.: HY-114558
CAS No.: 10453-86-8
Purity:  98.66%
Synonyms: Benzofuroline; Isathrine; Resmethrin(mixture of isomers)
Research Areas:  

Others

Resmethrin (Benzofuroline) is a reproductively toxic compound that inhibits spermatogenesis and induces apoptosis of germ cells in mouse testis culture in vitro, but has no significant toxicity to supporting cells and interstitial cells.
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Cat. No.: HY-E70001
Target:  

Others

Research Areas:  

Endocrinology

Recombinant Human Luteinizing Hormone is a recombinant form of Luteinizing hormone (human) (HY-P2293). Luteinizing hormone (human), a heterodimeric glycoprotein hormone produced by the pituitary gland (LH), plays key roles in human reproduction .
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Cat. No.: HY-121779
CAS No.: 3424-82-6
Synonyms: 2,4'-DDE; 2,4-Dichlorodiphenyldichloroethylene; 2,4'-DDE; o,p'-Dichlorodiphenyldichloroethylene
Target:  

Insecticide

Research Areas:  

Endocrinology

o,p'-DDE (2,4-Dichlorodiphenyldichloroethylene) is a metabolite and degradation product of the organochlorine pesticide DDT. It accumulates in smallmouth buffalo, channel catfish, and largemouth bass, and in sediments from DDT manufacturing plants around the Huntsville Spring Branch-Indian Creek tributary system, where it is considered a persistent organic pollutant (POP). o,p'-DDE inhibits estrogen binding to the rainbow trout estrogen receptor (rtER) with an IC50 value of 3.2 μM. It induces concentration-dependent estradiol secretion in co-cultures of granulosa and theca cells isolated from porcine follicles. In ovo exposure to o,p'-DDE increases follicular degeneration and reduces testis size in Japanese medaka (O. latipes).
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Cat. No.: HY-145548
CAS No.: 122068-08-0
Target:  

Endogenous Metabolite

Research Areas:  

Others

cis-4,10,13,16-Docosatetraenoic acid is a long chain polyunsaturated fatty acid derived from the lipids of rat testis .
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Cat. No.: HY-120958
CAS No.: 68378-49-4
Purity:  95.6%
Synonyms: C24:6n-3
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

Nisinic acid (C24:6n-3) is a very long chain polyunsaturated fatty acid (VLCPUFA) that is a component of triglycerides and cholesterol esters in mouse and rat testis .
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Cat. No.: HY-W011094R
CAS No.: 1477-57-2
Win 18446 is an orally active testes-specific enzyme ALDH1a2 inhibitor, with an IC50 of 0.3 μM. Win 18446 reversibly inhibits spermatogenesis in many species and inhibits Retinoic acid (HY-14649) biosynthesis from Retinol (HY-B1342) within the testes .
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Cat. No.: HY-W342930
CAS No.: 5858-33-3
Synonyms: Acid Red 17
Bordeaux Red (Acid Red 17) is a redox indicator that can be used for cytoplasm staining, such as spleen, testis, and liver slice staining. Bordeaux Red is a kind of biological materials or organic compounds that are widely used in life science research .
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