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vanillic acid

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Bacterial (2) Biochemical Assay Reagents (1) Calcium Channel (1) COX (2) Dopamine Receptor (2) Drug Derivative (1) Drug Metabolite (2) Endogenous Metabolite (5) Environmental Pollutants (1) HIV Integrase (1) Isotope-Labeled Compounds (2) NF-κB (2) NO Synthase (2) Parasite (2) Reactive Oxygen Species (ROS) (3) Reference Standards (5) Wnt (3)
By Research Areas:	Cancer (3) Infection (6) Inflammation/Immunology (5) Metabolic Disease (4) Neurological Disease (3)

Inhibitors & Agonists

Biochemical Assay Reagents

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0708

Vanillic acid 2 Publications Verification	NF-κB Bacterial Endogenous Metabolite	Infection Inflammation/Immunology
Vanillic acid is a flavoring agent found in edible plants and fruits, also found in Angelica sinensis. Vanillic acid inhibits NF-κB activation. Anti-inflammatory, antibacterial, and chemopreventive effects .

HY-75342

Methyl vanillate 2 Publications Verification	Wnt Reactive Oxygen Species (ROS) Endogenous Metabolite	Inflammation/Immunology Cancer
Methyl vanillate, one of the ingredients in Oryza sativa Linn., is a Wnt/β-catenin pathway activator . A benzoate ester that is the methyl ester of vanillic acid. It has a role as an antioxidant and a plant metabolite.

HY-N7080

Dihydroferulic acid Hydroferulic acid	Drug Metabolite	Metabolic Disease
Dihydroferulic acid (Hydroferulic acid) is one of the main metabolites of curcumin and antioxidant/radical-scavenging properties with an IC₅₀ value of 19.5 μM. Dihydroferulic acid is a metabolite of human gut microflora as well as a precursor of vanillic acid .

HY-107969

Haloperidol decanoate	Dopamine Receptor COX NO Synthase	Neurological Disease Cancer
Haloperidol decanoate is a depot preparation of haloperidol, a commonly used butyrophenone derivative with antipsychotic activity. Haloperidol decanoate can increase the striatal D₂ receptor in rat. Haloperidol decanoate can improve conditions of psychoses (mainly schizophrenia). Haloperidol decanoate can lead to increased accumulation of the dopamine metabolites homo-vanillic acid. Haloperidol decanoate can reduce intestinal transport, increase gastric emptying and reduce acid output in rat model .

HY-114760

Vanillic acid glucoside vanillic acid 4-β-D-glucoside	Others	Others
Vanillic acid glucoside (Vanillic acid 4-β-D-glucoside), a hydrolyzable tannin, is isolated from the fruits of C. annuum as well as the leaves of various additional plants. Vanillic acid glucoside can be phytotoxic against different species.

HY-N0708R

Vanillic acid (Standard)	Reference Standards NF-κB Bacterial Endogenous Metabolite	Infection Inflammation/Immunology
Vanillic acid (Standard) is the analytical standard of Vanillic acid. This product is intended for research and analytical applications. Vanillic acid is a flavoring agent found in edible plants and fruits, also found in Angelica sinensis. Vanillic acid inhibits NF-κB activation. Anti-inflammatory, antibacterial, and chemopreventive effects .

HY-W250112

Lignin alkali	Environmental Pollutants Biochemical Assay Reagents	Others
Lignin alkali acts as a decomposer, depolymerizer and structural modifier. Lignin alkali is recovered from lignocellulosic biomass via alkaline pretreatment. Lignin alkali consists of p-hydroxyphenyl, guaiacyl and syringyl propanoid units. Lignin alkali can be custom-converted into high-value-added chemicals and materials. Lignin alkali exhibits significant application potential in the fields of biomass refining and high-value utilization .

HY-W778225

Vanillic acid-13C6	Isotope-Labeled Compounds	Infection
Vanillic acid- ¹³C6 is the ¹³C labeled isotope of Vanillic acid- ¹³C6(HY-N0708 ).Vanillic acid is a flavoring agent found in edible plants and fruits, and in the root of angelica. Vanillic acid inhibits NF-κB activation. It has anti-inflammatory and antimicrobial activities.

HY-W009993

3,4-Methylenedioxycinnamic acid	Parasite	Infection Metabolic Disease
3,4-Methylenedioxycinnamic acid is an inhibitor of the 4-hydroxycinnamoyl-CoA ligase (4CL) with a K_i of 100 μM. 3,4-Methylenedioxycinnamic acid exhibits the K_m value for the substrate ferulic acid of 4CL is 8.4 μM.3,4-Methylenedioxycinnamic acid increases the formation of soluble phenolics in particular of vanillic acid. 3,4-Methylenedioxycinnamic acid demonstrates larvicidal activity .

HY-75342S

Methyl vanillate-d3	Wnt Endogenous Metabolite Reactive Oxygen Species (ROS) Isotope-Labeled Compounds	Inflammation/Immunology
Methyl vanillate-d₃ is deuterated labeled Methyl vanillate (HY-75342). Methyl vanillate, one of the ingredients in Oryza sativa Linn., is a Wnt/β-catenin pathway activator . A benzoate ester that is the methyl ester of vanillic acid. It has a role as an antioxidant and a plant metabolite.

HY-75342R

Methyl vanillate (Standard)	Reference Standards Wnt Reactive Oxygen Species (ROS) Endogenous Metabolite	Inflammation/Immunology Cancer
Methyl vanillate (Standard) is the analytical standard of Methyl vanillate. This product is intended for research and analytical applications. Methyl vanillate, one of the ingredients in Oryza sativa Linn., is a Wnt/β-catenin pathway activator[1]. A benzoate ester that is the methyl ester of vanillic acid. It has a role as an antioxidant and a plant metabolite.

HY-N7080R

Dihydroferulic acid (Standard) Hydroferulic acid (Standard)	Drug Metabolite Reference Standards	Metabolic Disease
Dihydroferulic acid (Standard) is the analytical standard of Dihydroferulic acid. This product is intended for research and analytical applications. Dihydroferulic acid (Hydroferulic acid) is one of the main metabolites of curcumin and antioxidant/radical-scavenging properties with an IC50 value of 19.5 μM. Dihydroferulic acid is a metabolite of human gut microflora as well as a precursor of vanillic acid[1][2].

HY-130358

PDDHV	Calcium Channel	Neurological Disease
PDDHV is a calcium absorption inducer and may achieve 45Ca ²⁺ influx by stimulating vanillic acid receptor VR1. PDDHV induces 45Ca ²⁺ uptake (EC₅₀: 70 nM) in rat dorsal root ganglion neurons (expressing native vanilloid receptors) and calcium mobilization (EC₅₀: 125 nM) in VR1-transfected CHO cells. PDDHV also inhibits [3H]-resiniferatoxin (RTX) binding to the dorsal root ganglion membrane in rats .

HY-107969R

Haloperidol decanoate (Standard)	Dopamine Receptor Reference Standards COX NO Synthase	Neurological Disease
Haloperidol decanoate (Standard) is the analytical standard of Haloperidol decanoate. This product is intended for research and analytical applications. Haloperidol decanoate is a depot preparation of haloperidol, a commonly used butyrophenone derivative with antipsychotic activity. Haloperidol decanoate can increase the striatal D₂ receptor in rat. Haloperidol decanoate can improve conditions of psychoses (mainly schizophrenia). Haloperidol decanoate can lead to increased accumulation of the dopamine metabolites homo-vanillic acid. Haloperidol decanoate can reduce intestinal transport, increase gastric emptying and reduce acid output in rat model .

HY-N17982

Vanillic acid 4-O-β-D-glucopyranoside	HIV Integrase	Infection
Vanillic acid 4-O-β-D-glucopyranoside is a vanillic acid glycoside with moderate antioxidant activity. Vanillic acid 4-O-β-D-glucopyranoside scavenges DPPH free radicals and superoxide anion radicals, and inhibits AAPH-induced lipid peroxidation in the linoleic acid system. The IC₅₀ value of Vanillic acid 4-O-β-D-glucopyranoside against HIV-1 integrase is >100 μg/mL, indicating that it is not an effective HIV-1 integrase inhibitor. Vanillic acid 4-O-β-D-glucopyranoside is isolable from the ethyl acetate extract of Gardeniae Fructus.

HY-N17058

1-O-Vanilloylglucose vanillic acid glucosyl ester	Drug Derivative	Others
1-O-Vanilloylglucose (Vanillic acid glucosyl ester) is a natural phenolic compound.

HY-W009993R

3,4-Methylenedioxycinnamic acid (Standard)	Parasite Reference Standards	Infection Metabolic Disease
3,4-Methylenedioxycinnamic acid (Standard) is the analytical standard of 3,4-Methylenedioxycinnamic acid (HY-W009993). This product is intended for research and analytical applications. 3,4-Methylenedioxycinnamic acid is an inhibitor of the 4-hydroxycinnamoyl-CoA ligase (4CL) with a Ki of 100 μM. 3,4-Methylenedioxycinnamic acid exhibits the Km value for the substrate ferulic acid of 4CL is 8.4 μM.3,4-Methylenedioxycinnamic acid increases the formation of soluble phenolics in particular of vanillic acid. 3,4-Methylenedioxycinnamic acid demonstrates larvicidal activity .

Cat. No.	Product Name	Type

HY-W250112

Lignin alkali	Biochemical Assay Reagents
Lignin alkali acts as a decomposer, depolymerizer and structural modifier. Lignin alkali is recovered from lignocellulosic biomass via alkaline pretreatment. Lignin alkali consists of p-hydroxyphenyl, guaiacyl and syringyl propanoid units. Lignin alkali can be custom-converted into high-value-added chemicals and materials. Lignin alkali exhibits significant application potential in the fields of biomass refining and high-value utilization .

Lignin alkali

Biochemical Assay Reagents

Lignin alkali acts as a decomposer, depolymerizer and structural modifier. Lignin alkali is recovered from lignocellulosic biomass via alkaline pretreatment. Lignin alkali consists of p-hydroxyphenyl, guaiacyl and syringyl propanoid units. Lignin alkali can be custom-converted into high-value-added chemicals and materials. Lignin alkali exhibits significant application potential in the fields of biomass refining and high-value utilization .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0708

Vanillic acid 2 Publications Verification	Classification of Application Fields Plants Endogenous metabolite Monophenols Immune System Disorder Microorganisms Ketones, Aldehydes, Acids Disease markers Phenols Umbelliferae Inflammation/Immunology Disease Research Fields Echinacea angustifolia DC. Source Classification	NF-κB Bacterial Endogenous Metabolite
Vanillic acid is a flavoring agent found in edible plants and fruits, also found in Angelica sinensis. Vanillic acid inhibits NF-κB activation. Anti-inflammatory, antibacterial, and chemopreventive effects .

HY-75342

Methyl vanillate 2 Publications Verification	Monophenols Microorganisms Oryza sativa Linn. Gramineae Phenols Plants Source Classification	Wnt Reactive Oxygen Species (ROS) Endogenous Metabolite
Methyl vanillate, one of the ingredients in Oryza sativa Linn., is a Wnt/β-catenin pathway activator . A benzoate ester that is the methyl ester of vanillic acid. It has a role as an antioxidant and a plant metabolite.

HY-N7080

Dihydroferulic acid Hydroferulic acid	Pseudostellaria heterophylla (Miq.) Pax Classification of Application Fields Metabolic Disease Plants Endogenous metabolite Caryophyllaceae Human Gut Microbiota Metabolites Monophenols Microorganisms Ketones, Aldehydes, Acids Phenols Disease Research Fields Source Classification	Drug Metabolite
Dihydroferulic acid (Hydroferulic acid) is one of the main metabolites of curcumin and antioxidant/radical-scavenging properties with an IC₅₀ value of 19.5 μM. Dihydroferulic acid is a metabolite of human gut microflora as well as a precursor of vanillic acid .

HY-114760

Vanillic acid glucoside vanillic acid 4-β-D-glucoside	Ketones, Aldehydes, Acids Thalictrum delavayi Franch. Plants Rhamnaceae Source Classification	Others
Vanillic acid glucoside (Vanillic acid 4-β-D-glucoside), a hydrolyzable tannin, is isolated from the fruits of C. annuum as well as the leaves of various additional plants. Vanillic acid glucoside can be phytotoxic against different species.

HY-N0708R

Vanillic acid (Standard)	Structural Classification Monophenols Immune System Disorder Microorganisms Ketones, Aldehydes, Acids Disease markers Phenols Umbelliferae Plants Endogenous metabolite Echinacea angustifolia DC. Source Classification	Reference Standards NF-κB Bacterial Endogenous Metabolite
Vanillic acid (Standard) is the analytical standard of Vanillic acid. This product is intended for research and analytical applications. Vanillic acid is a flavoring agent found in edible plants and fruits, also found in Angelica sinensis. Vanillic acid inhibits NF-κB activation. Anti-inflammatory, antibacterial, and chemopreventive effects .

HY-W009993

3,4-Methylenedioxycinnamic acid	Ketones, Aldehydes, Acids Piperaceae Plants Piper nigrum Linn. Source Classification	Parasite
3,4-Methylenedioxycinnamic acid is an inhibitor of the 4-hydroxycinnamoyl-CoA ligase (4CL) with a K_i of 100 μM. 3,4-Methylenedioxycinnamic acid exhibits the K_m value for the substrate ferulic acid of 4CL is 8.4 μM.3,4-Methylenedioxycinnamic acid increases the formation of soluble phenolics in particular of vanillic acid. 3,4-Methylenedioxycinnamic acid demonstrates larvicidal activity .

HY-75342R

Methyl vanillate (Standard)	Structural Classification Monophenols Microorganisms Oryza sativa Linn. Gramineae Phenols Plants Source Classification	Reference Standards Wnt Reactive Oxygen Species (ROS) Endogenous Metabolite
Methyl vanillate (Standard) is the analytical standard of Methyl vanillate. This product is intended for research and analytical applications. Methyl vanillate, one of the ingredients in Oryza sativa Linn., is a Wnt/β-catenin pathway activator[1]. A benzoate ester that is the methyl ester of vanillic acid. It has a role as an antioxidant and a plant metabolite.

HY-N7080R

Dihydroferulic acid (Standard) Hydroferulic acid (Standard)	Structural Classification Human Gut Microbiota Metabolites Monophenols Microorganisms Pseudostellaria heterophylla (Miq.) Pax Ketones, Aldehydes, Acids Phenols Plants Endogenous metabolite Caryophyllaceae Source Classification	Drug Metabolite Reference Standards
Dihydroferulic acid (Standard) is the analytical standard of Dihydroferulic acid. This product is intended for research and analytical applications. Dihydroferulic acid (Hydroferulic acid) is one of the main metabolites of curcumin and antioxidant/radical-scavenging properties with an IC50 value of 19.5 μM. Dihydroferulic acid is a metabolite of human gut microflora as well as a precursor of vanillic acid[1][2].

HY-N17982

Vanillic acid 4-O-β-D-glucopyranoside	Structural Classification Simple Phenylpropanols Rubiaceae Phenylpropanoids Plants Gardenia jasminoides Ellis Source Classification	HIV Integrase
Vanillic acid 4-O-β-D-glucopyranoside is a vanillic acid glycoside with moderate antioxidant activity. Vanillic acid 4-O-β-D-glucopyranoside scavenges DPPH free radicals and superoxide anion radicals, and inhibits AAPH-induced lipid peroxidation in the linoleic acid system. The IC₅₀ value of Vanillic acid 4-O-β-D-glucopyranoside against HIV-1 integrase is >100 μg/mL, indicating that it is not an effective HIV-1 integrase inhibitor. Vanillic acid 4-O-β-D-glucopyranoside is isolable from the ethyl acetate extract of Gardeniae Fructus.

HY-N17058

1-O-Vanilloylglucose vanillic acid glucosyl ester	Structural Classification Amomum villosum var. xanthioides (Wall. ex Baker) T. L. Wu & S. J. Chen Monophenols Phenols Amomum villosum Lour. Plants Source Classification Zingiberaceae	Drug Derivative
1-O-Vanilloylglucose (Vanillic acid glucosyl ester) is a natural phenolic compound.

HY-W009993R

3,4-Methylenedioxycinnamic acid (Standard)	Ketones, Aldehydes, Acids Piperaceae Plants Piper nigrum Linn. Source Classification	Parasite Reference Standards
3,4-Methylenedioxycinnamic acid (Standard) is the analytical standard of 3,4-Methylenedioxycinnamic acid (HY-W009993). This product is intended for research and analytical applications. 3,4-Methylenedioxycinnamic acid is an inhibitor of the 4-hydroxycinnamoyl-CoA ligase (4CL) with a Ki of 100 μM. 3,4-Methylenedioxycinnamic acid exhibits the Km value for the substrate ferulic acid of 4CL is 8.4 μM.3,4-Methylenedioxycinnamic acid increases the formation of soluble phenolics in particular of vanillic acid. 3,4-Methylenedioxycinnamic acid demonstrates larvicidal activity .

Cat. No.	Product Name	Chemical Structure

HY-W778225

Vanillic acid-13C6
Vanillic acid- ¹³C6 is the ¹³C labeled isotope of Vanillic acid- ¹³C6(HY-N0708 ).Vanillic acid is a flavoring agent found in edible plants and fruits, and in the root of angelica. Vanillic acid inhibits NF-κB activation. It has anti-inflammatory and antimicrobial activities.

HY-75342S

Methyl vanillate-d3
Methyl vanillate-d₃ is deuterated labeled Methyl vanillate (HY-75342). Methyl vanillate, one of the ingredients in Oryza sativa Linn., is a Wnt/β-catenin pathway activator . A benzoate ester that is the methyl ester of vanillic acid. It has a role as an antioxidant and a plant metabolite.

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vanillic acid

Inhibitors & Agonists

Biochemical Assay Reagents

NaturalProducts

Isotope-Labeled Compounds

Natural
Products