SHP2-IN-31
SHP2-IN-31 is a SHP2 inhibitor, with IC50s of 13 nM (Wild-type SHP2), >10000 nM (SHP1), >10000 nM (SHP2 E76K) . SHP2-IN-31 inhibits pERK in a panel of tumor cells. SHP2-IN-31 inhibits tumor growth in RTK/KRAS-driven xenograft models.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 2411321-35-0
- Fòrmula: C21H26Cl2N4O2
- Peso molecular:437.36
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Chemical Information
-
No. CAS 2411321-35-0
-
Peso molecular 437.36
-
Fòrmula C21H26Cl2N4O2
-
SMILES
N[C@H]1C2(CO[C@H]1C)CCN(C3=C(C(N(C4=C(C(Cl)=CC=C4)Cl)C(C)=N3)=O)C)CC2
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)