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Art. -Nr.: HY-184372

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SIRT1-IN-7

SIRT1-IN-7 is a weak inhibitor of SIRT1 with an IC₅₀ > 100 μM. SIRT1-IN-7 can be used in cancer-related research, such as breast cancer research.

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CAS. Nr.: 720672-18-4
Formel: C₁₇H₉FN₄O₂S
Molecular Weight:352.34

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

SIRT1-IN-7 Chemical Structure

CAS. Nr.: 720672-18-4

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

SIRT1-IN-7 is a weak inhibitor of SIRT1 with an IC₅₀ > 100 μM. SIRT1-IN-7 can be used in cancer-related research, such as breast cancer research^[1].

IC₅₀ & Target

^[1]

SIRT1

Alle Sirtuin Isoform-spezifische Produkte anzeigen :

In Vitro

SIRT1-IN-7 (compound 27) exerts extremely weak inhibitory activity against purified SIRT1 enzyme, with an IC₅₀ greater than 100 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 720672-18-4
Molecular Weight 352.34
Formel C₁₇H₉FN₄O₂S
SMILES

FC1=CC=C(C2=CC=C(C3=NN4C(S3)=NN=C4C5=CC=CO5)O2)C=C1
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Wu J, et al. Structure-activity relationship and interaction studies of new SIRT1 inhibitors with the scaffold of 3-(furan-2-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole. Bioorganic & medicinal chemistry letters. 2014 Jul 15;24(14):3050-6. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

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100 mg

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- IC₅₀ & Target
- In Vitro
Chemical Information
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SIRT1-IN-7

Alle Sirtuin Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Beschreibung

IC50 & Target

In Vitro

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

SIRT1-IN-7 Related Classifications

HY-184372 Related Classifications

Bioz

Keywords

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