SLC26A3-IN-1
SLC26A3-IN-1 is an inhibitor of anion exchanger protein SLC26A3 (IC50=340 nM). SLC26A3 belongs to solute carrier (SLC) proteins, and the SLC26 family. SLC26 family has broad anion specificity for chloride, bicarbonate, sulfate and oxalate. SLC26A3 down-regulates in adenoma, DRA, involves in in intestinal absorption of chloride and oxalate. The loss of SLC26A3 function mutations is associated with chloride-losing diarrhea.
For research use only. We do not sell to patients.
- CAS No.: 307552-53-0
- Formula: C23H18O4
- Molecular Weight:358.39
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
SLC26A3-IN-1 (compound 4a) (10 μM; 10 min) produces 87% inhibition rate against SLC26A3[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 307552-53-0
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Molecular Weight 358.39
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Formula C23H18O4
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SMILES
O=C(C1=C(C2=CC=CC=C2)OC3=C1C=C(OCC4=C(C)C=CC=C4)C=C3)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SLC26A3-IN-1 Related Classifications
HY-149802 Related Classifications
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