SML-10-70-1
SML-10-70-1 is a ligand for RAS, which covalently modifies the K-Ras G12C mutant protein, and inhibits the phosphorylation of ERK and Akt. SML-10-70-1 inhibits the proliferation of cancer cells H23, H358 and A549 with IC50 of 26.6-47.6 μM.
For research use only. We do not sell to patients.
- CAS No.: 1536470-98-0
- Formula: C25H42ClN7O13P2
- Molecular Weight:746.04
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 1536470-98-0
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Molecular Weight 746.04
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Formula C25H42ClN7O13P2
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SMILES
O=C1C(N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](COP(OP(OCCNC(CCl)=O)(N[C@@H](C)C(OCC(CCC)CCC)=O)=O)(O)=O)O3)=C2N=C(N)N1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)