2. GPCR/G Protein MAPK/ERK Pathway
  3. Ras
  4. Sosimerasib

Sosimerasib is an orally active KRASG12C inhibitor. Sosimerasib can be used in research related to non-small cell lung cancer.

For research use only. We do not sell to patients.

Sosimerasib

Sosimerasib Chemical Structure

CAS No. : 2839563-01-6

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Based on 1 publication(s) in Google Scholar

Sosimerasib Related Antibodies

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Description

Sosimerasib is an orally active KRASG12C inhibitor. Sosimerasib can be used in research related to non-small cell lung cancer[1].

In Vitro

Sosimerasib exerts functional inhibitory effects on KRASG12C mutant proteins[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Sosimerasib Related Antibodies
Molecular Weight

688.19

Formula

C36H39ClFN7O4
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C(N1C[C@]2([H])C(N(CCN(C)C)C3=C(N2C[C@@]1([H])C)C4=C(N=C(C5=C(O)C=CC=C5F)C(Cl)=C4)N(C6=C(C(C)C)N=CC=C6C)C3=O)=O)C=C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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Sosimerasib Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sosimerasib2839563-01-6RasKRAS G12Cnon-small cell lung cancerKRAS G12C mutant proteinInhibitorinhibitorinhibit

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