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Cat. No.: HY-105890

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Spiroplatin

Name: Spiroplatin
Brand: MedChemExpress
SKU: HY-105890
Price: 358.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: TNO 6)

Spiroplatin is a Cisplatin (HY-17394) congener and has antitumor activity.

For research use only. We do not sell to patients.

CAS No.: 74790-08-2
Formula: C₈H₁₈N₂O₄PtS
Molecular Weight:433.39

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Spiroplatin Chemical Structure

CAS No.: 74790-08-2

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Spiroplatin is a Cisplatin (HY-17394) congener and has antitumor activity^[1].

All Lipoxygenase Isoforms :

Chemical Information

CAS No. 74790-08-2
Molecular Weight 433.39
Formula C₈H₁₈N₂O₄PtS
SMILES

O=S1([O-][Pt+2]2([NH2]CC3(C[NH2]2)CCCCC3)[O-]1)=O
Synonyms

TNO 6
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocols

All Animals and Diseases

Subcutaneous Cell-Line-Derived Xenograft
Subcutaneous cell-line-derived xenograft (CDX) models are established by implanting cultured human cancer cell lines into immunodeficient mice, where the injected cells form localized tumors that can be monitored in vivo as a measure of tumorigenic potential, growth kinetics, and treatment response. These models are widely used in oncology research because they allow reproducible tumor formation and enable comparative assessment of tumor growth between different cell lines or genetic manipulations in a controlled in vivo microenvironment. Subcutaneous implantation of cancer cells in immunodeficient mice is a standard approach for evaluating tumor growth behavior and therapeutic response across multiple cancer types, including prostate, esophageal, pancreatic, and colon cancer models.

Purity & Documentation

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Tanis BC, et al. Multicenter phase II study of spiroplatin. Oncology. 1992;49(2):99-103. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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