1. JAK/STAT Signaling
    Stem Cell/Wnt
  2. STAT
  3. Stafib-1

Stafib-1 

Cat. No.: HY-112647 Purity: ≥98.0%
Handling Instructions

Stafib-1 is the first selective inhibitor of the STAT5b SH2 domain, with a Ki of 44 nM and an IC50 of 154 nM.

For research use only. We do not sell to patients.

Stafib-1 Chemical Structure

Stafib-1 Chemical Structure

CAS No. : 1688703-26-5

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5 mg USD 220 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

Stafib-1 is the first selective inhibitor of the STAT5b SH2 domain, with a Ki of 44 nM and an IC50 of 154 nM[1].

IC50 & Target[1]

STAT5b

154 nM (IC50)

In Vitro

Stafib-1 is the first small molecule which inhibits the STAT5b SH2 domain with more than 50-fold selectivity over STAT5a[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

602.42

Formula

C₂₆H₂₄N₂O₁₁P₂

CAS No.

1688703-26-5

SMILES

O=C(C1=CC=C2C=C(OCC(NCC3=CC=C(OP(O)(O)=O)C(OP(O)(O)=O)=C3)=O)C=CC2=C1)NC4=CC=CC=C4

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
References

Purity: ≥98.0%

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Keywords:

Stafib-1Stafib1Stafib 1STATK562STAT5bInhibitorinhibitorinhibit

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Product Name:
Stafib-1
Cat. No.:
HY-112647
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