2. GPCR/G Protein Neuronal Signaling
  3. 5-HT Receptor
  4. Tiospirone

Tiospirone  (Synonyms: BMY 13859-1 free base)

Cat. No.: HY-105034
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Tiospirone is a 5-HT2 receptor antagonist with affinity for D2, 5-HT1a, and 5-HT7, and sigma receptors. Tiospirone decreases consumption of ethanol while increasing food intake of rats. Tiospirone can also reduce the reinforcing properties of Cocaine exhibited in the conditioned place preference paradigm.

For research use only. We do not sell to patients.

Tiospirone Chemical Structure

Tiospirone Chemical Structure

CAS No. : 87691-91-6

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Description

Tiospirone is a 5-HT2 receptor antagonist with affinity for D2, 5-HT1a, and 5-HT7, and sigma receptors. Tiospirone decreases consumption of ethanol while increasing food intake of rats. Tiospirone can also reduce the reinforcing properties of Cocaine exhibited in the conditioned place preference paradigm[1][2].

Molecular Weight

440.60

Formula

C24H32N4O2S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C1N(CCCCN2CCN(CC2)C3=NSC4=C3C=CC=C4)C(CC5(CCCC5)C1)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Tiospirone Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tiospirone87691-91-6BMY 13859-15-HT ReceptorSerotonin Receptor5-hydroxytryptamine ReceptorethanolCocainefood intakeInhibitorinhibitorinhibit

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