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Cat. No.: HY-173079

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TLR7 agonist 30

TLR7 agonist 30 (compound 2) is an agent-linker conjugate for ADC. TLR7 agonist 30 contains a TLR7 agonist (compound 1) and a cleavable linker, and has potent anti-tumor activity.

For research use only. We do not sell to patients.

Formula: C₇₁H₁₁₅N₁₅O₂₂
Molecular Weight:1530.76

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

TLR7 agonist 30 Chemical Structure

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Biological Activity

Description

TLR7 agonist 30 (compound 2) is an agent-linker conjugate for ADC. TLR7 agonist 30 contains a TLR7 agonist (compound 1) and a cleavable linker, and has potent anti-tumor activity^[1].

All Toll-like Receptor (TLR) Isoforms :

All Drug-Linker Conjugates for ADC Isoforms :

Chemical Information

Molecular Weight 1530.76
Formula C₇₁H₁₁₅N₁₅O₂₂
SMILES

OC1=NC2=C(N)N=C(OCCCC)N=C2N1CC3=CN=C(CN(C4CCC4)C(OCC5=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCOCCOCCOCCOCCN)=O)=O)=O)C=C5C(NCCNC(CCOCCOCCOCCOCCOCCOCCOCCOC)=O)=O)=O)C=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Sega E, et al. Targeted Delivery of TLR7 Agonists to the Tumor Microenvironment Enhances Tumor Immunity via Activation of Tumor-Resident Myeloid Cells. Bioconjug Chem. 2025 Feb 13. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Biological Activity
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Chemical Information
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References

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TLR7 agonist 30

All Toll-like Receptor (TLR) Isoforms

All Drug-Linker Conjugates for ADC Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

TLR7 agonist 30 Related Classifications

HY-173079 Related Classifications