1. Metabolic Enzyme/Protease
  2. ROR
  3. TMP780

TMP780 

Cat. No.: HY-102075B
Handling Instructions

TMP780 is an inverse agonist of RORγt with an IC50 of 13 nM. RORγt is a tractable drug target for the treatment of cutaneous inflammatory disorders.

For research use only. We do not sell to patients.

TMP780 Chemical Structure

TMP780 Chemical Structure

CAS No. : 1422053-03-9

Size Stock
100 mg   Get quote  
250 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Other Forms of TMP780:

Top Publications Citing Use of Products

View All ROR Isoform Specific Products:

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

TMP780 is an inverse agonist of RORγt with an IC50 of 13 nM. RORγt is a tractable drug target for the treatment of cutaneous inflammatory disorders[1].

IC50 & Target

IC50: 13 nM (RORγt)[1]

Molecular Weight

494.58

Formula

C₃₁H₃₀N₂O₄

CAS No.

1422053-03-9

SMILES

O=C(N[[email protected]](C1=CC=C(C)C=C1C)C2=CC=CC=C2)CC3=CC=C(OC([[email protected]@H](C4=C(C)ON=C4C)O)=C5)C5=C3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

TMP780TMP 780TMP-780RORRAR-related orphan receptorRORγtcutaneou,s inflammatorydisordersInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email address *

Phone number *

 

Organization name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
TMP780
Cat. No.:
HY-102075B
Quantity:
MCE Japan Authorized Agent: