TRPC6 antagonist-1
TRPC6 antagonist-1 (X26) is a TRPC6 antagonist with IC50 values of 0.97 μM, 3.93 μM, 5.77 μM and 4.37 μM for TRPC6, TRPC3, TRPC5 and TRPC7, respectively. TRPC6 antagonist-1 inhibits TGF-β1-induced myofibroblast differentiation, and attenuates renal fibrosis.
For research use only. We do not sell to patients.
- Formula: C26H32N4O2S
- Molecular Weight:464.62
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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Molecular Weight 464.62
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Formula C26H32N4O2S
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SMILES
COC1=C2C(SC(N(C(C3=CC=C(CCCC4)C4=C3)=O)CCNC5CNCCC5)=N2)=CC=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)